Pfizer
PFE
2,813 hedge funds and large institutions have $92.5B invested in Pfizer in 2025 Q3 according to their latest regulatory filings, with 204 funds opening new positions, 1,118 increasing their positions, 1,221 reducing their positions, and 153 closing their positions.
33% more first-time investments, than exits
New positions opened: 204 | Existing positions closed: 153
21% more funds holding in top 10
Funds holding in top 10: 29 → 35 (+6)
2% more capital invested
Capital invested by funds: $90.8B → $92.5B (+$1.7B)
0% more funds holding
Funds holding: 2,810 → 2,813 (+3)
8% less repeat investments, than reductions
Existing positions increased: 1,118 | Existing positions reduced: 1,221
1.79% less ownership
Funds ownership: 65.64% → 63.85% (-1.8%)
15% less call options, than puts
Call options by funds: $2.58B | Put options by funds: $3.03B
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Royal Bank of Canada
Toronto,
Ontario, Canada
|
+$240M |
| 2 |
Franklin Resources
San Mateo,
California
|
+$200M |
| 3 |
Marshall Wace
London,
United Kingdom
|
+$161M |
| 4 |
Neuberger Berman Group
New York
|
+$149M |
| 5 |
Ameriprise
Minneapolis,
Minnesota
|
+$148M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Massachusetts Financial Services
Boston,
Massachusetts
|
-$441M |
| 2 |
Wellington Management Group
Boston,
Massachusetts
|
-$408M |
| 3 |
Millennium Management
New York
|
-$302M |
| 4 |
BNP Paribas Financial Markets
Paris,
France
|
-$282M |
| 5 |
UBS AM
Chicago,
Illinois
|
-$239M |
PFE Hedge Fund Activity: Q3 2025 in Review
2,813 of the 7,624 institutional investors tracked by Wall St. Rank reported a position in Pfizer (PFE) for Q3 2025, worth a combined $92.5B — up 1.9% from $90.8B a quarter earlier.
Buyers outnumbered sellers: 204 funds opened new PFE positions and 153 closed out — a net gain of 51 holders — while 1,118 added to existing stakes and 1,221 trimmed.
The largest buyer was Royal Bank of Canada, adding an estimated $240M. The largest seller was Massachusetts Financial Services, cutting an estimated $441M.
- 2,813 institutional investors held Pfizer (PFE) as of Q3 2025, up from 2,810 in Q2 2025.
- Funds reported $92.5B of Pfizer stock for Q3 2025, up 1.9% quarter-over-quarter.
- 204 funds opened new Pfizer positions in Q3 2025 and 153 closed out, a net change of +51 holders.
- The largest Pfizer buyer in Q3 2025 was Royal Bank of Canada, an estimated $240M added.
- The largest Pfizer seller in Q3 2025 was Massachusetts Financial Services, an estimated $441M sold.
Based on aggregated 13F filings for Q3 2025.