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Outlook Therapeutics
OTLK

53 hedge funds and large institutions have $10.8M invested in Outlook Therapeutics in 2025 Q4 according to their latest regulatory filings, with 9 funds opening new positions, 19 increasing their positions, 7 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

171% more repeat investments, than reductions

Existing positions increased: 19 | Existing positions reduced: 7

149% more capital invested

Capital invested by funds: $4.32M → $10.8M (+$6.46M)

13% more first-time investments, than exits

New positions opened: 9 | Existing positions closed: 8

1.46% more ownership

Funds ownership: 9.18% → 10.64% (+1.5%)

2% less funds holding

Funds holding: 54 → 53 (-1)

67% less call options, than puts

Call options by funds: $1.26M | Put options by funds: $3.89M

Holders
53
Holders Change
-1
Holders Change %
-1.85%
% of All Funds
0.64%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
9
Increased
19
Reduced
7
Closed
8
Calls
$1.26M
Puts
$3.89M
Net Calls
-$2.62M
Net Calls Change
-$2.89M

Top Buyers

Rank Fund Capital Flow
1
SSA
Schonfeld Strategic Advisors
New York
+$2.76M
2
Marshall Wace
Marshall Wace
United Kingdom
+$477K
3
UBS Group
UBS Group
Switzerland
+$258K
4
Vanguard Group
Vanguard Group
Pennsylvania
+$196K
5
State Street
State Street
Massachusetts
+$140K

Top Sellers

Rank Fund Capital Flow
1
Bank of America
Bank of America
North Carolina
-$144K
2
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$63K
3
Millennium Management
Millennium Management
New York
-$48.1K
4
TSS
Two Sigma Securities
New York
-$37.8K
5
SA
Sanctuary Advisors
Indiana
-$35.5K
Name Holding Trade Value Shares
Change 		Change in
Stake
TRCT
26
Tower Research Capital (TRC)
New York
$20.3K +$20.6K +12,873 New
Squarepoint
27
Squarepoint
New York
$18.5K +$18.7K +11,699 New
HI
28
Harbour Investments
Wisconsin
$16K +$14.9K +9,331 +1,137%
Osaic Holdings
29
Osaic Holdings
Arizona
$14.2K – – –
Morgan Stanley
30
Morgan Stanley
New York
$9.52K +$8.39K +5,249 +677%
Jones Financial Companies
31
Jones Financial Companies
Missouri
$3.95K – – –
Wells Fargo
32
Wells Fargo
California
$3.92K +$1.71K +1,070 +76%
Northwestern Mutual Wealth Management
33
Northwestern Mutual Wealth Management
Wisconsin
$3.36K – – –
Citigroup
34
Citigroup
New York
$2.46K -$23K -14,424 -90%
FDCDDQ
35
Federation des caisses Desjardins du Quebec
Quebec, Canada
$2.07K – – –
AA
36
Ancora Advisors
Ohio
$1.74K – – –
IAIM
37
International Assets Investment Management
Florida
$1.58K +$1.6K +1,000 New
EWA
38
EverSource Wealth Advisors
Alabama
$1.1K – – –
Royal Bank of Canada
39
Royal Bank of Canada
Ontario, Canada
$1K -$6.56K -4,106 -86%
Fidelity Investments
40
Fidelity Investments
Massachusetts
$957 +$799 +500 +472%
FFO
41
Fortitude Family Office
Arizona
$670 +$677 +424 New
BNP Paribas Financial Markets
42
BNP Paribas Financial Markets
France
$482 – – –
SS
43
SBI Securities
Japan
$332 – – –
AAG
44
Armstrong Advisory Group
Massachusetts
$283 – – –
Bank of America
45
Bank of America
North Carolina
$203 -$144K -90,347 -100%
LFG
46
Larson Financial Group
Missouri
$158 – – –
PWMG
47
Prestige Wealth Management Group
New Jersey
$98 – – –
SWM
48
SHP Wealth Management
Massachusetts
$93 +$94 +59 New
IA
49
IFP Advisors
Florida
$79 +$80 +50 New
JP Morgan Chase
50
JP Morgan Chase
New York
$24 – – –
1
2
3

OTLK Hedge Fund Activity: Q4 2025 in Review

53 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Outlook Therapeutics (OTLK) for Q4 2025, worth a combined $10.8M — up 149% from $4.32M a quarter earlier.

Buyers outnumbered sellers: 9 funds opened new OTLK positions and 8 closed out — a net gain of 1 holder — while 19 added to existing stakes and 7 trimmed.

The largest buyer was Schonfeld Strategic Advisors, adding an estimated $2.76M. The largest seller was Bank of America, cutting an estimated $144K.

  • 53 institutional investors held Outlook Therapeutics (OTLK) as of Q4 2025, down from 54 in Q3 2025.
  • Funds reported $10.8M of Outlook Therapeutics stock for Q4 2025, up 149% quarter-over-quarter.
  • 9 funds opened new Outlook Therapeutics positions in Q4 2025 and 8 closed out, a net change of +1 holder.
  • The largest Outlook Therapeutics buyer in Q4 2025 was Schonfeld Strategic Advisors, an estimated $2.76M added.
  • The largest Outlook Therapeutics seller in Q4 2025 was Bank of America, an estimated $144K sold.

Based on aggregated 13F filings for Q4 2025.