OS Therapies Inc
OSTX
25 hedge funds and large institutions have $2.49M invested in OS Therapies Inc in 2025 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 8 increasing their positions, 4 reducing their positions, and 6 closing their positions.
100% more repeat investments, than reductions
Existing positions increased: 8 | Existing positions reduced: 4
17% more first-time investments, than exits
New positions opened: 7 | Existing positions closed: 6
0.1% more ownership
Funds ownership: 4.94% → 5.04% (+0.1%)
0% more funds holding
Funds holding: 25 → 25 (0)
19% less capital invested
Capital invested by funds: $3.07M → $2.49M (-$580K)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Vanguard Group
Malvern,
Pennsylvania
|
+$635K |
| 2 |
Geode Capital Management
Boston,
Massachusetts
|
+$105K |
| 3 |
Jane Street
New York
|
+$50K |
| 4 |
UBS Group
Zurich,
Switzerland
|
+$32.3K |
| 5 |
Northern Trust
Chicago,
Illinois
|
+$27.1K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Marshall Wace
London,
United Kingdom
|
-$160K |
| 2 |
VF
Virtu Financial
New York
|
-$149K |
| 3 |
Millennium Management
New York
|
-$113K |
| 4 |
GSC
Ground Swell Capital
Folly Beach,
South Carolina
|
-$40.1K |
| 5 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$29.3K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
GSC
26
Ground Swell Capital
Folly Beach,
South Carolina
| – | -$40.1K | -20,462 | Closed |
|
|
27
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
| – | -$29.3K | -14,961 | Closed |
|
|
SMH
28
Sanders Morris Harris
Houston,
Texas
| – | -$23.5K | -12,000 | Closed |
|
|
TSS
29
Two Sigma Securities
New York
| – | -$20.1K | -10,237 | Closed |
|
30
JP Morgan Chase
New York
| – | -$25 | -13 | Closed |
|
|
FIA
31
FNY Investment Advisers
New York
| – | +$180 | +100 | New |
|
OSTX Hedge Fund Activity: Q4 2025 in Review
25 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in OS Therapies Inc (OSTX) for Q4 2025, worth a combined $2.49M — down 19% from $3.07M a quarter earlier.
Buyers outnumbered sellers: 7 funds opened new OSTX positions and 6 closed out — a net gain of 1 holder — while 8 added to existing stakes and 4 trimmed.
The largest buyer was Vanguard Group, adding an estimated $635K. The largest seller was Marshall Wace, cutting an estimated $160K.
- 25 institutional investors held OS Therapies Inc (OSTX) as of Q4 2025, unchanged from Q3 2025.
- Funds reported $2.49M of OS Therapies Inc stock for Q4 2025, down 19% quarter-over-quarter.
- 7 funds opened new OS Therapies Inc positions in Q4 2025 and 6 closed out, a net change of +1 holder.
- The largest OS Therapies Inc buyer in Q4 2025 was Vanguard Group, an estimated $635K added.
- The largest OS Therapies Inc seller in Q4 2025 was Marshall Wace, an estimated $160K sold.
Based on aggregated 13F filings for Q4 2025.