Organogenesis Holdings
ORGO
147 hedge funds and large institutions have $360M invested in Organogenesis Holdings in 2025 Q4 according to their latest regulatory filings, with 35 funds opening new positions, 42 increasing their positions, 47 reducing their positions, and 9 closing their positions.
289% more first-time investments, than exits
New positions opened: 35 | Existing positions closed: 9
48% more call options, than puts
Call options by funds: $90K | Put options by funds: $61K
25% more capital invested
Capital invested by funds: $288M → $360M (+$71.3M)
21% more funds holding
Funds holding: 121 → 147 (+26)
0.87% more ownership
Funds ownership: 53.89% → 54.76% (+0.87%)
11% less repeat investments, than reductions
Existing positions increased: 42 | Existing positions reduced: 47
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
D.E. Shaw & Co
New York
|
+$7.16M |
| 2 |
Jane Street
New York
|
+$3.85M |
| 3 |
Assenagon Asset Management
Senningerberg,
Luxembourg
|
+$3.3M |
| 4 |
Citadel Advisors
Miami,
Florida
|
+$2.76M |
| 5 |
Millennium Management
New York
|
+$1.94M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
FLAM
First Light Asset Management
Edina,
Minnesota
|
-$17.6M |
| 2 |
SCM
Soleus Capital Management
Greenwich,
Connecticut
|
-$10.4M |
| 3 |
UBS Group
Zurich,
Switzerland
|
-$1.75M |
| 4 |
Connor, Clark & Lunn Investment Management (CC&L)
Vancouver,
British Columbia, Canada
|
-$1.73M |
| 5 |
Acadian Asset Management
Boston,
Massachusetts
|
-$1.42M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
151
Group One Trading
Chicago,
Illinois
| – | -$18.4K | -3,800 | Closed |
|
|
ASN
152
Advisory Services Network
Atlanta,
Georgia
| – | -$1.21K | -286 | Closed |
|
153
Jones Financial Companies
Des Peres,
Missouri
| – | -$1.05K | -255 | Closed |
|
|
FC
154
Financial Consulate
Hunt Valley,
Maryland
| – | -$254 | -60 | Closed |
|
|
CA
155
Clearstead Advisors
Cleveland,
Ohio
| – | -$55 | -13 | Closed |
|
ORGO Hedge Fund Activity: Q4 2025 in Review
147 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Organogenesis Holdings (ORGO) for Q4 2025, worth a combined $360M — up 25% from $288M a quarter earlier.
Buyers outnumbered sellers: 35 funds opened new ORGO positions and 9 closed out — a net gain of 26 holders — while 42 added to existing stakes and 47 trimmed.
The largest buyer was D.E. Shaw & Co, adding an estimated $7.16M. The largest seller was First Light Asset Management, cutting an estimated $17.6M.
- 147 institutional investors held Organogenesis Holdings (ORGO) as of Q4 2025, up from 121 in Q3 2025.
- Funds reported $360M of Organogenesis Holdings stock for Q4 2025, up 25% quarter-over-quarter.
- 35 funds opened new Organogenesis Holdings positions in Q4 2025 and 9 closed out, a net change of +26 holders.
- The largest Organogenesis Holdings buyer in Q4 2025 was D.E. Shaw & Co, an estimated $7.16M added.
- The largest Organogenesis Holdings seller in Q4 2025 was First Light Asset Management, an estimated $17.6M sold.
Based on aggregated 13F filings for Q4 2025.