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Organogenesis Holdings
ORGO

147 hedge funds and large institutions have $360M invested in Organogenesis Holdings in 2025 Q4 according to their latest regulatory filings, with 35 funds opening new positions, 42 increasing their positions, 47 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed

289% more first-time investments, than exits

New positions opened: 35 | Existing positions closed: 9

48% more call options, than puts

Call options by funds: $90K | Put options by funds: $61K

25% more capital invested

Capital invested by funds: $288M → $360M (+$71.3M)

21% more funds holding

Funds holding: 121 → 147 (+26)

0.87% more ownership

Funds ownership: 53.89% → 54.76% (+0.87%)

11% less repeat investments, than reductions

Existing positions increased: 42 | Existing positions reduced: 47

Holders
147
Holders Change
+26
Holders Change %
+21.49%
% of All Funds
1.79%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
35
Increased
42
Reduced
47
Closed
9
Calls
$90K
Puts
$61K
Net Calls
+$29K
Net Calls Change
-$248K

Top Buyers

1
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$7.16M
2
Jane Street
Jane Street
New York
+$3.85M
3
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
+$3.3M
4
Citadel Advisors
Citadel Advisors
Florida
+$2.76M
5
Millennium Management
Millennium Management
New York
+$1.94M

Top Sellers

1
FLAM
First Light Asset Management
Minnesota
-$17.6M
2
SCM
Soleus Capital Management
Connecticut
-$10.4M
3
UBS Group
UBS Group
Switzerland
-$1.75M
4
Connor, Clark & Lunn Investment Management (CC&L)
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
-$1.73M
5
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$1.42M
Name Holding Trade Value Shares
Change 		Change in
Stake
Goldman Sachs
26
Goldman Sachs
New York
$2.17M +$916K +188,958 +82%
WDG
27
Wealth Dimensions Group
Ohio
$2.11M – – –
Point72 Asset Management
28
Point72 Asset Management
Connecticut
$2.02M +$1.89M +389,246 New
Wells Fargo
29
Wells Fargo
California
$1.83M +$1.51M +311,409 +742%
SBH
30
Segall Bryant & Hamill
Illinois
$1.65M +$2.89K +597 +0.2%
HWM
31
HighMark Wealth Management
Minnesota
$1.57M +$48.5K +10,000 +3%
Bank of New York Mellon
32
Bank of New York Mellon
New York
$1.57M -$334K -68,927 -19%
HF
33
HRT Financial
New York
$1.42M +$1.33M +274,814 New
N
34
Nuveen
North Carolina
$1.42M +$562K +115,890 +73%
Two Sigma Investments
35
Two Sigma Investments
New York
$1.38M +$1.05M +216,066 +427%
Fidelity Investments
36
Fidelity Investments
Massachusetts
$1.38M +$120K +24,828 +10%
Balyasny Asset Management
37
Balyasny Asset Management
Illinois
$1.36M +$1.27M +261,915 New
Wellington Management Group
38
Wellington Management Group
Massachusetts
$1.12M -$62.3K -12,855 -6%
HWAM
39
Hennion & Walsh Asset Management
New Jersey
$1.08M +$240K +49,601 +31%
GCP
40
GSA Capital Partners
United Kingdom
$992K +$928K +191,465 New
Invesco
41
Invesco
Georgia
$908K +$76.5K +15,790 +10%
Prudential Financial
42
Prudential Financial
New Jersey
$882K +$453K +93,590 +122%
American Century Companies
43
American Century Companies
Missouri
$880K -$1.26K -260 -0.2%
TI
44
Trexquant Investment
Connecticut
$772K +$722K +149,107 New
Squarepoint
45
Squarepoint
New York
$697K +$652K +134,631 New
UBS Group
46
UBS Group
Switzerland
$687K -$1.75M -360,708 -73%
AllianceBernstein
47
AllianceBernstein
Tennessee
$644K -$124K -25,600 -17%
Barclays
48
Barclays
United Kingdom
$551K +$42.1K +8,697 +9%
Los Angeles Capital Management
49
Los Angeles Capital Management
California
$541K -$99.7K -20,576 -14%
ACM
50
Aquatic Capital Management
Illinois
$526K +$397K +81,893 +417%
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ORGO Hedge Fund Activity: Q4 2025 in Review

147 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Organogenesis Holdings (ORGO) for Q4 2025, worth a combined $360M — up 25% from $288M a quarter earlier.

Buyers outnumbered sellers: 35 funds opened new ORGO positions and 9 closed out — a net gain of 26 holders — while 42 added to existing stakes and 47 trimmed.

The largest buyer was D.E. Shaw & Co, adding an estimated $7.16M. The largest seller was First Light Asset Management, cutting an estimated $17.6M.

  • 147 institutional investors held Organogenesis Holdings (ORGO) as of Q4 2025, up from 121 in Q3 2025.
  • Funds reported $360M of Organogenesis Holdings stock for Q4 2025, up 25% quarter-over-quarter.
  • 35 funds opened new Organogenesis Holdings positions in Q4 2025 and 9 closed out, a net change of +26 holders.
  • The largest Organogenesis Holdings buyer in Q4 2025 was D.E. Shaw & Co, an estimated $7.16M added.
  • The largest Organogenesis Holdings seller in Q4 2025 was First Light Asset Management, an estimated $17.6M sold.

Based on aggregated 13F filings for Q4 2025.