OptiNose
OPTN
OPTN was delisted on the 20th of May, 2025.
55 hedge funds and large institutions have $116M invested in OptiNose in 2022 Q4 according to their latest regulatory filings, with 13 funds opening new positions, 18 increasing their positions, 15 reducing their positions, and 8 closing their positions.
100% more funds holding in top 10
Funds holding in top 10: 1 → 2 (+1)
63% more first-time investments, than exits
New positions opened: 13 | Existing positions closed: 8
20% more repeat investments, than reductions
Existing positions increased: 18 | Existing positions reduced: 15
15% more call options, than puts
Call options by funds: $211K | Put options by funds: $183K
10% more funds holding
Funds holding: 50 → 55 (+5)
1.21% more ownership
Funds ownership: 2.61% → 3.83% (+1.2%)
3% less capital invested
Capital invested by funds: $120M → $116M (-$3.14M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
GPP
Great Point Partners
Greenwich,
Connecticut
|
+$20M |
| 2 |
Fidelity Investments
Boston,
Massachusetts
|
+$5.49M |
| 3 |
AC
Armistice Capital
New York
|
+$5.05M |
| 4 |
NCM
Nantahala Capital Management
New Canaan,
Connecticut
|
+$3.67M |
| 5 |
VCIM
Velan Capital Investment Management
Alpharetta,
Georgia
|
+$3.34M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
GC
GMT Capital
Atlanta,
Georgia
|
-$4.07M |
| 2 |
SCM
Stonepine Capital Management
Bend,
Oregon
|
-$3.78M |
| 3 |
EI
EAM Investors
Solana Beach,
California
|
-$1.24M |
| 4 |
Millennium Management
New York
|
-$406K |
| 5 |
OM
Opaleye Management
Boston,
Massachusetts
|
-$333K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
51
Wells Fargo
San Francisco,
California
| $1.1K | -$43.8K | -1,153 | -97% |
|
52
Daiwa Securities Group
Tokyo,
Japan
| $1K | – | – | – |
|
53
First Manhattan
New York
| $925 | -$2.54K | -67 | -67% |
|
|
GC
54
GMT Capital
Atlanta,
Georgia
| – | -$4.07M | -74,047 | Closed |
|
|
EI
55
EAM Investors
Solana Beach,
California
| – | -$1.24M | -22,501 | Closed |
|
|
OM
56
Opaleye Management
Boston,
Massachusetts
| – | -$333K | -6,065 | Closed |
|
57
Two Sigma Investments
New York
| – | -$140K | -2,553 | Closed |
|
58
Squarepoint
New York
| – | -$75K | -1,357 | Closed |
|
|
AWA
59
Arete Wealth Advisors
Chicago,
Illinois
| – | -$44K | -800 | Closed |
|
60
Federated Hermes
Pittsburgh,
Pennsylvania
| – | -$1K | -14 | Closed |
|
|
OPW
61
Oxler Private Wealth
Rye Brook,
New York
| – | -$366 | -7 | Closed |
|
62
Royal Bank of Canada
Toronto,
Ontario, Canada
| – | -$190 | -5 | -42% |
|
OPTN Hedge Fund Activity: Q4 2022 in Review
55 of the 6,222 institutional investors tracked by Wall St. Rank reported a position in OptiNose (OPTN) for Q4 2022, worth a combined $116M — down 2.6% from $120M a quarter earlier.
Buyers outnumbered sellers: 13 funds opened new OPTN positions and 8 closed out — a net gain of 5 holders — while 18 added to existing stakes and 15 trimmed.
The largest buyer was Great Point Partners, opening a new position worth an estimated $20M. The largest seller was GMT Capital, exiting entirely with an estimated $4.07M sold.
- 55 institutional investors held OptiNose (OPTN) as of Q4 2022, up from 50 in Q3 2022.
- Funds reported $116M of OptiNose stock for Q4 2022, down 2.6% quarter-over-quarter.
- 13 funds opened new OptiNose positions in Q4 2022 and 8 closed out, a net change of +5 holders.
- The largest OptiNose buyer in Q4 2022 was Great Point Partners, an estimated $20M added.
- The largest OptiNose seller in Q4 2022 was GMT Capital, an estimated $4.07M sold.
Based on aggregated 13F filings for Q4 2022.