OptiNose
OPTN
OPTN was delisted on the 20th of May, 2025.
44 hedge funds and large institutions have $66.9M invested in OptiNose in 2021 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 8 increasing their positions, 14 reducing their positions, and 15 closing their positions.
8% more capital invested
Capital invested by funds: $62.2M → $66.9M (+$4.72M)
0.93% more ownership
Funds ownership: 2.61% → 3.53% (+0.93%)
10% less funds holding
Funds holding: 49 → 44 (-5)
33% less first-time investments, than exits
New positions opened: 10 | Existing positions closed: 15
42% less call options, than puts
Call options by funds: $67K | Put options by funds: $116K
43% less repeat investments, than reductions
Existing positions increased: 8 | Existing positions reduced: 14
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Fidelity Investments
Boston,
Massachusetts
|
+$8.85M |
| 2 |
SCM
Stonepine Capital Management
Bend,
Oregon
|
+$8.58M |
| 3 |
BL
Bleichroeder LP
New York
|
+$8.3M |
| 4 |
Vanguard Group
Malvern,
Pennsylvania
|
+$1.88M |
| 5 |
EIP
Easterly Investment Partners
Beverly,
Massachusetts
|
+$337K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
OM
Opaleye Management
Boston,
Massachusetts
|
-$4.68M |
| 2 |
PCMI
Paradigm Capital Management Inc
Albany,
New York
|
-$2.11M |
| 3 |
GCP
GSA Capital Partners
London,
United Kingdom
|
-$1.58M |
| 4 |
EIM
Essex Investment Management
Boston,
Massachusetts
|
-$1.46M |
| 5 |
Jacobs Levy Equity Management
Florham Park,
New Jersey
|
-$1.33M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
51
Russell Investments Group
London,
United Kingdom
| – | -$79K | -1,774 | Closed |
|
52
Citadel Advisors
Miami,
Florida
| – | -$39.8K | -1,189 | Closed |
|
|
CF
53
Clarity Financial
Houston,
Texas
| – | -$43K | -966 | Closed |
|
|
PPA
54
Parametric Portfolio Associates
Seattle,
Washington
| – | -$34K | -759 | Closed |
|
55
Royal Bank of Canada
Toronto,
Ontario, Canada
| – | -$19.3K | -576 | -99% |
|
56
Osaic Holdings
Scottsdale,
Arizona
| – | -$6K | -113 | Closed |
|
|
OSAM
57
O'Shaughnessy Asset Management
Stamford,
Connecticut
| – | -$1K | -16 | Closed |
|
58
Wells Fargo
San Francisco,
California
| – | -$469 | -14 | -45% |
|
59
Group One Trading
Chicago,
Illinois
| – | -$435 | -13 | -39% |
|
OPTN Hedge Fund Activity: Q4 2021 in Review
44 of the 6,499 institutional investors tracked by Wall St. Rank reported a position in OptiNose (OPTN) for Q4 2021, worth a combined $66.9M — up 7.6% from $62.2M a quarter earlier.
Sellers outnumbered buyers: 15 funds closed out of OPTN and 10 opened new positions — a net loss of 5 holders — while 14 trimmed existing stakes and 8 added.
The largest buyer was Fidelity Investments, adding an estimated $8.85M. The largest seller was Opaleye Management, exiting entirely with an estimated $4.68M sold.
- 44 institutional investors held OptiNose (OPTN) as of Q4 2021, down from 49 in Q3 2021.
- Funds reported $66.9M of OptiNose stock for Q4 2021, up 7.6% quarter-over-quarter.
- 10 funds opened new OptiNose positions in Q4 2021 and 15 closed out, a net change of -5 holders.
- The largest OptiNose buyer in Q4 2021 was Fidelity Investments, an estimated $8.85M added.
- The largest OptiNose seller in Q4 2021 was Opaleye Management, an estimated $4.68M sold.
Based on aggregated 13F filings for Q4 2021.