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Nuvalent
NUVL

237 hedge funds and large institutions have $8.04B invested in Nuvalent in 2025 Q4 according to their latest regulatory filings, with 60 funds opening new positions, 101 increasing their positions, 47 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

675% more call options, than puts

Call options by funds: $5.53M | Put options by funds: $714K

233% more first-time investments, than exits

New positions opened: 60 | Existing positions closed: 18

115% more repeat investments, than reductions

Existing positions increased: 101 | Existing positions reduced: 47

28% more capital invested

Capital invested by funds: $6.26B → $8.04B (+$1.78B)

21% more funds holding

Funds holding: 196 → 237 (+41)

10.17% more ownership

Funds ownership: 108.62% → 118.79% (+10%)

20% less funds holding in top 10

Funds holding in top 10: 10 → 8 (-2)

Holders
237
Holders Change
+41
Holders Change %
+20.92%
% of All Funds
2.88%
Holding in Top 10
8
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-20%
% of All Funds
0.1%
New
60
Increased
101
Reduced
47
Closed
18
Calls
$5.53M
Puts
$714K
Net Calls
+$4.82M
Net Calls Change
+$8.11M

Top Buyers

1
BG
Bellevue Group
Switzerland
+$102M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$82.8M
3
AllianceBernstein
AllianceBernstein
Tennessee
+$72.5M
4
BlackRock
BlackRock
New York
+$70.9M
5
Vanguard Group
Vanguard Group
Pennsylvania
+$63M

Top Sellers

1
VPC
Vestal Point Capital
New York
-$104M
2
CC
Commodore Capital
New York
-$83.8M
3
DM
Deerfield Management
New York
-$73.2M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$67.9M
5
WP
Woodline Partners
California
-$45.3M
Name Holding Trade Value Shares
Change 		Change in
Stake
Mariner
151
Mariner
Kansas
$311K +$305K +3,094 New
Prudential Financial
152
Prudential Financial
New Jersey
$308K -$238K -2,415 -44%
QCM
153
Quantinno Capital Management
New York
$305K +$299K +3,028 New
FCM
154
Farallon Capital Management
California
$302K – – –
HNWAG
155
High Net Worth Advisory Group
Florida
$302K – – –
Principal Financial Group
156
Principal Financial Group
Iowa
$297K -$33.7K -342 -10%
Public Employees Retirement Association of Colorado
157
Public Employees Retirement Association of Colorado
Colorado
$289K – – –
BHCM
158
Brevan Howard Capital Management
Jersey
$282K +$276K +2,803 New
US Bancorp
159
US Bancorp
Minnesota
$263K +$53.6K +544 +26%
LPL Financial
160
LPL Financial
California
$255K +$250K +2,539 New
VIA
161
Virtus Investment Advisers
Connecticut
$255K +$106K +1,077 +74%
FFA
162
Farther Finance Advisors
California
$252K +$127K +1,289 +106%
CIBC Asset Management
163
CIBC Asset Management
Ontario, Canada
$251K +$246K +2,495 New
Allspring Global Investments
164
Allspring Global Investments
North Carolina
$249K +$244K +2,470 New
FC
165
FORA Capital
Florida
$218K +$214K +2,171 New
WWM
166
Whalen Wealth Management
Nevada
$216K +$212K +2,148 New
SLAM
167
Swiss Life Asset Management
$202K +$198K +2,009 New
PIC
168
Portland Investment Counsel
Ontario, Canada
$201K +$197K +2,000 New
PNC Financial Services Group
169
PNC Financial Services Group
Pennsylvania
$169K -$1.58K -16 -0.9%
AB
170
Amalgamated Bank
New York
$158K +$35.1K +356 +29%
KBC Group
171
KBC Group
Belgium
$154K +$29.3K +297 +24%
Royal Bank of Canada
172
Royal Bank of Canada
Ontario, Canada
$146K -$5.34M -54,162 -97%
GFM
173
GF Fund Management
China
$143K -$1.48K -15 -1%
Carson Wealth (CWM LLC)
174
Carson Wealth (CWM LLC)
Nebraska
$132K +$1.58K +16 +1%
NS
175
NBC Securities
Alabama
$125K +$123K +1,247 New
5 6
7
8 9

NUVL Hedge Fund Activity: Q4 2025 in Review

237 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Nuvalent (NUVL) for Q4 2025, worth a combined $8.04B — up 28% from $6.26B a quarter earlier.

Buyers outnumbered sellers: 60 funds opened new NUVL positions and 18 closed out — a net gain of 42 holders — while 101 added to existing stakes and 47 trimmed.

The largest buyer was Bellevue Group, opening a new position worth an estimated $102M. The largest seller was Vestal Point Capital, cutting an estimated $104M.

  • 237 institutional investors held Nuvalent (NUVL) as of Q4 2025, up from 196 in Q3 2025.
  • Funds reported $8.04B of Nuvalent stock for Q4 2025, up 28% quarter-over-quarter.
  • 60 funds opened new Nuvalent positions in Q4 2025 and 18 closed out, a net change of +42 holders.
  • The largest Nuvalent buyer in Q4 2025 was Bellevue Group, an estimated $102M added.
  • The largest Nuvalent seller in Q4 2025 was Vestal Point Capital, an estimated $104M sold.

Based on aggregated 13F filings for Q4 2025.