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Nuvalent
NUVL

237 hedge funds and large institutions have $8.04B invested in Nuvalent in 2025 Q4 according to their latest regulatory filings, with 60 funds opening new positions, 101 increasing their positions, 47 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

675% more call options, than puts

Call options by funds: $5.53M | Put options by funds: $714K

233% more first-time investments, than exits

New positions opened: 60 | Existing positions closed: 18

115% more repeat investments, than reductions

Existing positions increased: 101 | Existing positions reduced: 47

28% more capital invested

Capital invested by funds: $6.26B → $8.04B (+$1.78B)

21% more funds holding

Funds holding: 196237 (+41)

10.17% more ownership

Funds ownership: 108.62%118.79% (+10%)

20% less funds holding in top 10

Funds holding in top 10: 108 (-2)

Holders
237
Holders Change
+41
Holders Change %
+20.92%
% of All Funds
2.88%
Holding in Top 10
8
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-20%
% of All Funds
0.1%
New
60
Increased
101
Reduced
47
Closed
18
Calls
$5.53M
Puts
$714K
Net Calls
+$4.82M
Net Calls Change
+$8.11M
Name Holding Trade Value Shares
Change
Change in
Stake
DCM
26
Driehaus Capital Management
Illinois
$48.6M +$26.3M +266,948 +123%
HRCM
27
Hood River Capital Management
Florida
$47.8M +$46.9M +475,440 New
Charles Schwab
28
Charles Schwab
California
$45.6M +$4.81M +48,758 +12%
Invesco
29
Invesco
Georgia
$44.2M +$40M +405,543 +1,201%
Franklin Resources
30
Franklin Resources
California
$41.4M +$24.8M +251,220 +157%
Northern Trust
31
Northern Trust
Illinois
$41.3M +$2.85M +28,954 +8%
UBS Group
32
UBS Group
Switzerland
$40.1M +$18.3M +185,932 +87%
American Century Companies
33
American Century Companies
Missouri
$37.6M +$1.11M +11,301 +3%
FTM
34
First Turn Management
California
$37.1M -$2.57M -26,057 -7%
CS
35
Candriam SCA
Luxembourg
$36M +$2.79M +28,292 +9%
Pictet Asset Management
36
Pictet Asset Management
Switzerland
$35.8M -$2.85M -28,895 -8%
AAA
37
Affinity Asset Advisors
New York
$32.5M -$6.09M -61,784 -16%
SCM
38
Silverarc Capital Management
Massachusetts
$31.3M -$6M -60,870 -16%
TLP
39
Tri Locum Partners
New York
$30.9M +$30.3M +307,371 New
ACH
40
ArrowMark Colorado Holdings
Colorado
$29.8M -$6.56M -66,556 -18%
Lord, Abbett & Co
41
Lord, Abbett & Co
New Jersey
$28.3M +$27.7M +281,215 New
FCM
42
Frontier Capital Management
Massachusetts
$27.2M +$26.7M +270,470 New
DCM
43
Defilade Capital Management
California
$27.1M +$26.5M +269,043 New
Morgan Stanley
44
Morgan Stanley
New York
$26.9M -$761K -7,721 -3%
Citadel Advisors
45
Citadel Advisors
Florida
$19.6M +$16.3M +164,930 +546%
Bank of America
46
Bank of America
North Carolina
$18.1M +$1.89M +19,183 +12%
BNP Paribas Financial Markets
47
BNP Paribas Financial Markets
France
$17.5M +$3.56M +36,121 +26%
VOYA Investment Management
48
VOYA Investment Management
Georgia
$17.4M +$3.73M +37,785 +28%
Aberdeen Group
49
Aberdeen Group
United Kingdom
$16.6M +$8.73M +88,489 +115%
RPAM
50
Rhenman & Partners Asset Management
Sweden
$16.4M +$10.9M +110,850 +211%

NUVL Hedge Fund Activity: Q4 2025 in Review

237 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Nuvalent (NUVL) for Q4 2025, worth a combined $8.04B — up 28% from $6.26B a quarter earlier.

Buyers outnumbered sellers: 60 funds opened new NUVL positions and 18 closed out — a net gain of 42 holders — while 101 added to existing stakes and 47 trimmed.

The largest buyer was Bellevue Group, opening a new position worth an estimated $102M. The largest seller was Vestal Point Capital, cutting an estimated $104M.

  • 237 institutional investors held Nuvalent (NUVL) as of Q4 2025, up from 196 in Q3 2025.
  • Funds reported $8.04B of Nuvalent stock for Q4 2025, up 28% quarter-over-quarter.
  • 60 funds opened new Nuvalent positions in Q4 2025 and 18 closed out, a net change of +42 holders.
  • The largest Nuvalent buyer in Q4 2025 was Bellevue Group, an estimated $102M added.
  • The largest Nuvalent seller in Q4 2025 was Vestal Point Capital, an estimated $104M sold.

Based on aggregated 13F filings for Q4 2025.