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Nuvalent
NUVL

237 hedge funds and large institutions have $8.04B invested in Nuvalent in 2025 Q4 according to their latest regulatory filings, with 60 funds opening new positions, 101 increasing their positions, 47 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

675% more call options, than puts

Call options by funds: $5.53M | Put options by funds: $714K

233% more first-time investments, than exits

New positions opened: 60 | Existing positions closed: 18

115% more repeat investments, than reductions

Existing positions increased: 101 | Existing positions reduced: 47

28% more capital invested

Capital invested by funds: $6.26B → $8.04B (+$1.78B)

21% more funds holding

Funds holding: 196237 (+41)

10.17% more ownership

Funds ownership: 108.62%118.79% (+10%)

20% less funds holding in top 10

Funds holding in top 10: 108 (-2)

Holders
237
Holders Change
+41
Holders Change %
+20.92%
% of All Funds
2.88%
Holding in Top 10
8
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-20%
% of All Funds
0.1%
New
60
Increased
101
Reduced
47
Closed
18
Calls
$5.53M
Puts
$714K
Net Calls
+$4.82M
Net Calls Change
+$8.11M
Name Holding Trade Value Shares
Change
Change in
Stake
FFO
226
Fortitude Family Office
Arizona
$704
MCM
227
MAI Capital Management
Ohio
$604
EP
228
Essential Partners
California
$402
BTI
229
Blue Trust Inc
Georgia
$402 +$394 +4 New
SS
230
SBI Securities
Japan
$302 +$99 +1 +50%
KFAS
231
Keating Financial Advisory Services
Kansas
$302 +$296 +3 New
KG
232
Kilter Group
New York
$302 +$296 +3 New
CA
233
CoreCap Advisors
Michigan
$201
CIAM
234
Caitong International Asset Management
Hong Kong
$201 +$197 +2 New
PWA
235
Principia Wealth Advisory
Texas
$101 +$99 +1 New
TPCW
236
TD Private Client Wealth
New York
$101 +$99 +1 New
DF
237
Dunhill Financial
United Kingdom
$82 +$99 +1 New
SCM
238
Soleus Capital Management
Connecticut
-$7.61M -88,000 Closed
AA
239
ALPS Advisors
Colorado
-$2.67M -30,886 Closed
D.E. Shaw & Co
240
D.E. Shaw & Co
New York
-$2.36M -27,311 Closed
JFG
241
Jefferies Financial Group
New York
-$2.18M -25,160 Closed
CF
242
Cantor Fitzgerald
New York
-$1.95M -22,500 Closed
Hudson Bay Capital Management
243
Hudson Bay Capital Management
Connecticut
-$1.3M -15,000 Closed
ECM
244
ExodusPoint Capital Management
New York
-$630K -7,289 Closed
SIM
245
Sandia Investment Management
Massachusetts
-$476K -5,500 Closed
EFMC
246
Empire Financial Management Company
New York
-$432K -5,000 Closed
SSA
247
Schonfeld Strategic Advisors
New York
-$348K -4,026 Closed
FGP
248
Freestone Grove Partners
California
-$342K -3,960 Closed
JGC
249
J. Goldman & Co
New York
-$254K -2,936 Closed
Simplex Trading
250
Simplex Trading
Illinois
-$169K -1,709 Closed

NUVL Hedge Fund Activity: Q4 2025 in Review

237 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Nuvalent (NUVL) for Q4 2025, worth a combined $8.04B — up 28% from $6.26B a quarter earlier.

Buyers outnumbered sellers: 60 funds opened new NUVL positions and 18 closed out — a net gain of 42 holders — while 101 added to existing stakes and 47 trimmed.

The largest buyer was Bellevue Group, opening a new position worth an estimated $102M. The largest seller was Vestal Point Capital, cutting an estimated $104M.

  • 237 institutional investors held Nuvalent (NUVL) as of Q4 2025, up from 196 in Q3 2025.
  • Funds reported $8.04B of Nuvalent stock for Q4 2025, up 28% quarter-over-quarter.
  • 60 funds opened new Nuvalent positions in Q4 2025 and 18 closed out, a net change of +42 holders.
  • The largest Nuvalent buyer in Q4 2025 was Bellevue Group, an estimated $102M added.
  • The largest Nuvalent seller in Q4 2025 was Vestal Point Capital, an estimated $104M sold.

Based on aggregated 13F filings for Q4 2025.