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Neurocrine Biosciences

585 hedge funds and large institutions have $12.4B invested in Neurocrine Biosciences in 2025 Q2 according to their latest regulatory filings, with 77 funds opening new positions, 224 increasing their positions, 221 reducing their positions, and 70 closing their positions.

New
Increased
Maintained
Reduced
Closed

45% more funds holding in top 10

Funds holding in top 10: 1116 (+5)

40% more call options, than puts

Call options by funds: $37.7M | Put options by funds: $27M

16% more capital invested

Capital invested by funds: $10.7B → $12.4B (+$1.75B)

10% more first-time investments, than exits

New positions opened: 77 | Existing positions closed: 70

3.08% more ownership

Funds ownership: 96.86%99.95% (+3.1%)

1% more repeat investments, than reductions

Existing positions increased: 224 | Existing positions reduced: 221

0% less funds holding

Funds holding: 586585 (-1)

Holders
585
Holders Change
-1
Holders Change %
-0.17%
% of All Funds
7.7%
Holding in Top 10
16
Holding in Top 10 Change
+5
Holding in Top 10 Change %
+45.45%
% of All Funds
0.21%
New
77
Increased
224
Reduced
221
Closed
70
Calls
$37.7M
Puts
$27M
Net Calls
+$10.7M
Net Calls Change
-$17.5M
Name Holding Trade Value Shares
Change
Change in
Stake
Adage Capital Partners
51
Adage Capital Partners
Massachusetts
$42.9M +$39.2M +341,578 New
Citigroup
52
Citigroup
New York
$40.5M -$16.5M -144,125 -31%
RhumbLine Advisers
53
RhumbLine Advisers
Massachusetts
$38.9M -$607K -5,296 -2%
SCM
54
Sarissa Capital Management
Connecticut
$38.1M -$684K -5,965 -2%
Swiss National Bank
55
Swiss National Bank
Switzerland
$37.6M +$1.59M +13,900 +5%
CS
56
Candriam SCA
Luxembourg
$37.5M -$3.7M -32,289 -10%
Invesco
57
Invesco
Georgia
$36.4M -$31.9M -278,075 -49%
Wells Fargo
58
Wells Fargo
California
$35.7M +$3.32M +28,947 +11%
Barclays
59
Barclays
United Kingdom
$34.1M +$8.16M +71,172 +36%
Macquarie Group
60
Macquarie Group
Australia
$34M +$4.49M +39,154 +17%
HRCM
61
Hood River Capital Management
Florida
$32.4M -$9.13M -79,626 -24%
PA
62
Perceptive Advisors
New York
$32.1M +$17.8M +155,000 +155%
Fidelity Investments
63
Fidelity Investments
Massachusetts
$32M +$18.2M +158,926 +166%
RG
64
Renaissance Group
Kentucky
$31.6M +$4.54M +39,632 +19%
Connor, Clark & Lunn Investment Management (CC&L)
65
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$31.3M +$22.1M +192,768 +345%
Principal Financial Group
66
Principal Financial Group
Iowa
$30.6M -$538K -4,690 -2%
Sumitomo Mitsui Trust Group
67
Sumitomo Mitsui Trust Group
Japan
$29.6M +$462K +4,030 +2%
N
68
Nuveen
North Carolina
$28.8M -$6.61M -57,634 -20%
Amundi
69
Amundi
France
$28.4M -$1.38M -11,992 -5%
SEI Investments
70
SEI Investments
Pennsylvania
$27.7M +$9.1M +79,334 +56%
EHI
71
Eagle Health Investments
Connecticut
$27.3M -$906K -7,900 -4%
ZIG
72
Zurich Insurance Group
Switzerland
$26.6M +$24.3M +211,911 New
Capital Fund Management (CFM)
73
Capital Fund Management (CFM)
France
$25.6M +$3.21M +27,987 +16%
Envestnet Asset Management
74
Envestnet Asset Management
Illinois
$24.9M +$8.69M +75,733 +62%
American Century Companies
75
American Century Companies
Missouri
$24M +$9.17K +80 +0%

NBIX Hedge Fund Activity: Q2 2025 in Review

585 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Neurocrine Biosciences (NBIX) for Q2 2025, worth a combined $12.4B — up 16% from $10.7B a quarter earlier.

Buyers outnumbered sellers: 77 funds opened new NBIX positions and 70 closed out — a net gain of 7 holders — while 224 added to existing stakes and 221 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $182M. The largest seller was BlackRock, cutting an estimated $198M.

  • 585 institutional investors held Neurocrine Biosciences (NBIX) as of Q2 2025, down from 586 in Q1 2025.
  • Funds reported $12.4B of Neurocrine Biosciences stock for Q2 2025, up 16% quarter-over-quarter.
  • 77 funds opened new Neurocrine Biosciences positions in Q2 2025 and 70 closed out, a net change of +7 holders.
  • The largest Neurocrine Biosciences buyer in Q2 2025 was JP Morgan Chase, an estimated $182M added.
  • The largest Neurocrine Biosciences seller in Q2 2025 was BlackRock, an estimated $198M sold.

Based on aggregated 13F filings for Q2 2025.