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Neurocrine Biosciences

586 hedge funds and large institutions have $10.7B invested in Neurocrine Biosciences in 2025 Q1 according to their latest regulatory filings, with 74 funds opening new positions, 190 increasing their positions, 251 reducing their positions, and 83 closing their positions.

New
Increased
Maintained
Reduced
Closed

44% more call options, than puts

Call options by funds: $92.7M | Put options by funds: $64.6M

3.45% more ownership

Funds ownership: 93.41%96.86% (+3.4%)

2% less funds holding

Funds holding: 600586 (-14)

11% less first-time investments, than exits

New positions opened: 74 | Existing positions closed: 83

15% less funds holding in top 10

Funds holding in top 10: 1311 (-2)

17% less capital invested

Capital invested by funds: $12.9B → $10.7B (-$2.23B)

24% less repeat investments, than reductions

Existing positions increased: 190 | Existing positions reduced: 251

Holders
586
Holders Change
-14
Holders Change %
-2.33%
% of All Funds
7.86%
Holding in Top 10
11
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-15.38%
% of All Funds
0.15%
New
74
Increased
190
Reduced
251
Closed
83
Calls
$92.7M
Puts
$64.6M
Net Calls
+$28.2M
Net Calls Change
+$24.4M
Name Holding Trade Value Shares
Change
Change in
Stake
ClearBridge Investments
51
ClearBridge Investments
New York
$37.9M +$2.91M +23,003 +7%
HRCM
52
Hood River Capital Management
Florida
$37.3M -$2.27M -17,894 -5%
Axa
53
Axa
France
$36.9M +$4.56M +35,995 +12%
CS
54
Candriam SCA
Luxembourg
$36.6M +$3.4M +26,868 +9%
Ameriprise
55
Ameriprise
Minnesota
$34.9M -$12.4M -97,769 -24%
RhumbLine Advisers
56
RhumbLine Advisers
Massachusetts
$34.8M -$759K -5,992 -2%
SCM
57
Sarissa Capital Management
Connecticut
$34.2M
N
58
Nuveen
North Carolina
$31.7M +$2.35M +18,516 +7%
Swiss National Bank
59
Swiss National Bank
Switzerland
$31.6M +$25.3K +200 +0.1%
RSCM
60
Rock Springs Capital Management
Maryland
$30.9M -$55.9M -441,500 -61%
Wells Fargo
61
Wells Fargo
California
$28.2M +$1.12M +8,812 +4%
Principal Financial Group
62
Principal Financial Group
Iowa
$27.5M -$513K -4,049 -2%
HSBC Holdings
63
HSBC Holdings
United Kingdom
$26.9M +$3.89M +30,681 +14%
SFM
64
Soros Fund Management
New York
$26.5M +$5.04M +39,823 +20%
BNP Paribas Financial Markets
65
BNP Paribas Financial Markets
France
$26.2M -$6.67M -52,625 -18%
Sumitomo Mitsui Trust Group
66
Sumitomo Mitsui Trust Group
Japan
$25.6M -$177K -1,399 -0.6%
Macquarie Group
67
Macquarie Group
Australia
$25.6M -$5.42M -42,778 -16%
EHI
68
Eagle Health Investments
Connecticut
$24.9M +$8.88M +70,100 +45%
Aberdeen Group
69
Aberdeen Group
United Kingdom
$24.4M +$8.08M +63,770 +41%
Amundi
70
Amundi
France
$23.8M -$3.89M -30,673 -12%
RG
71
Renaissance Group
Kentucky
$23.5M -$693K -5,472 -3%
Alyeska Investment Group
72
Alyeska Investment Group
Illinois
$22.8M -$5.39M -42,560 -17%
Barclays
73
Barclays
United Kingdom
$22.1M +$2.77M +21,850 +12%
Ensign Peak Advisors
74
Ensign Peak Advisors
Utah
$21.5M +$2.67M +21,050 +12%
Canada Pension Plan Investment Board
75
Canada Pension Plan Investment Board
Ontario, Canada
$21.2M +$19.9M +157,399 +462%

NBIX Hedge Fund Activity: Q1 2025 in Review

586 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Neurocrine Biosciences (NBIX) for Q1 2025, worth a combined $10.7B — down 17% from $12.9B a quarter earlier.

Sellers outnumbered buyers: 83 funds closed out of NBIX and 74 opened new positions — a net loss of 9 holders — while 251 trimmed existing stakes and 190 added.

The largest buyer was Dodge & Cox, adding an estimated $319M. The largest seller was Citadel Advisors, cutting an estimated $209M.

  • 586 institutional investors held Neurocrine Biosciences (NBIX) as of Q1 2025, down from 600 in Q4 2024.
  • Funds reported $10.7B of Neurocrine Biosciences stock for Q1 2025, down 17% quarter-over-quarter.
  • 74 funds opened new Neurocrine Biosciences positions in Q1 2025 and 83 closed out, a net change of -9 holders.
  • The largest Neurocrine Biosciences buyer in Q1 2025 was Dodge & Cox, an estimated $319M added.
  • The largest Neurocrine Biosciences seller in Q1 2025 was Citadel Advisors, an estimated $209M sold.

Based on aggregated 13F filings for Q1 2025.