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MPLT

MapLight Therapeutics

74 hedge funds and large institutions have $405M invested in MapLight Therapeutics in 2025 Q4 according to their latest regulatory filings, with 74 funds opening new positions, increasing their positions, reducing their positions, and closing their positions.

New
Increased
Maintained
Reduced
Closed

50.84% more ownership

Funds ownership: 0%50.84% (+51%)

Holders
74
Holders Change
+74
Holders Change %
% of All Funds
0.9%
Holding in Top 10
8
Holding in Top 10 Change
+8
Holding in Top 10 Change %
% of All Funds
0.1%
New
74
Increased
Reduced
Closed
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
DCM
26
DAFNA Capital Management
California
$2.53M +$2.41M +143,764 New
Charles Schwab
27
Charles Schwab
California
$2.43M +$2.32M +138,427 New
Northern Trust
28
Northern Trust
Illinois
$2.1M +$2M +119,557 New
SGM
29
Seven Grand Managers
New York
$1.76M +$1.68M +100,000 New
SC
30
Stempoint Capital
New York
$1.76M +$1.68M +100,000 New
BGM
31
Burkehill Global Management
New York
$1.32M +$1.26M +75,000 New
Ameriprise
32
Ameriprise
Minnesota
$1.17M +$1.12M +66,872 New
DP
33
Diadema Partners
New Jersey
$1.12M +$1.07M +63,791 New
O
34
OrbiMed
New York
$952K +$938K +56,000 New
Tudor Investment Corp
35
Tudor Investment Corp
Connecticut
$840K +$802K +47,840 New
Marshall Wace
36
Marshall Wace
United Kingdom
$697K +$664K +39,659 New
Bank of America
37
Bank of America
North Carolina
$664K +$634K +37,820 New
TD Asset Management
38
TD Asset Management
Ontario, Canada
$649K +$619K +36,960 New
Bank of New York Mellon
39
Bank of New York Mellon
New York
$630K +$601K +35,857 New
Barclays
40
Barclays
United Kingdom
$464K +$443K +26,415 New
Morgan Stanley
41
Morgan Stanley
New York
$408K +$389K +23,222 New
PAP
42
Persistent Asset Partners
Hong Kong
$382K +$365K +21,766 New
Nuveen
43
Nuveen
North Carolina
$355K +$338K +20,197 New
GCM
44
Ghisallo Capital Management
Massachusetts
$351K +$335K +20,000 New
Wells Fargo
45
Wells Fargo
California
$328K +$313K +18,687 New
UBS Group
46
UBS Group
Switzerland
$321K +$306K +18,290 New
OAM
47
Oxford Asset Management
United Kingdom
$312K +$298K +17,763 New
Millennium Management
48
Millennium Management
New York
$245K +$234K +13,945 New
RhumbLine Advisers
49
RhumbLine Advisers
Massachusetts
$240K +$229K +13,642 New
LCM
50
Lynx1 Capital Management
Puerto Rico
$237K +$226K +13,477 New

MPLT Hedge Fund Activity: Q4 2025 in Review

74 of the 8,256 institutional investors tracked by Wall St. Rank reported a position in MapLight Therapeutics (MPLT) for Q4 2025, worth a combined $405M.

Buyers outnumbered sellers: 74 funds opened new MPLT positions and 0 closed out — a net gain of 74 holders — while 0 added to existing stakes and 0 trimmed.

The largest buyer was Novo Holdings A/S, opening a new position worth an estimated $61.8M.

  • 74 institutional investors held MapLight Therapeutics (MPLT) as of Q4 2025, up from 0 in Q3 2025.
  • Funds reported $405M of MapLight Therapeutics stock for Q4 2025.
  • 74 funds opened new MapLight Therapeutics positions in Q4 2025 and 0 closed out, a net change of +74 holders.
  • The largest MapLight Therapeutics buyer in Q4 2025 was Novo Holdings A/S, an estimated $61.8M added.

Based on aggregated 13F filings for Q4 2025.