MBX

MBX Biosciences

136 hedge funds and large institutions have $1.53B invested in MBX Biosciences in 2025 Q4 according to their latest regulatory filings, with 44 funds opening new positions, 52 increasing their positions, 25 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed

more funds holding in top 10

Funds holding in top 10:

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more capital invested

Capital invested by funds: $ → $

more first-time investments, than exits

New positions opened: | Existing positions closed:

16% more funds holding

Funds holding: 117136 (+19)

34.41% less ownership

Funds ownership: 142.26%107.85% (-34%)

71% less call options, than puts

Call options by funds: $4.09M | Put options by funds: $14M

Holders
136
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
7
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$4.09M
Puts
$14M
Net Calls
Net Calls Change

Top Buyers

1 +$24.7M
2 +$23.3M
3 +$21.6M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$16.3M
5
State Street
State Street
Massachusetts
+$8.58M

Top Sellers

1 -$35.8M
2 -$25.8M
3 -$22.9M
4
WP
Woodline Partners
California
-$4.88M
5
BBA
Baker Bros. Advisors
New York
-$4.86M
Name Holding Trade Value Shares
Change
Change in
Stake
AC
101
AXQ Capital
New Jersey
$204K
SG Americas Securities
102
SG Americas Securities
New York
$150K
New York State Common Retirement Fund
103
New York State Common Retirement Fund
New York
$136K
TRCT
104
Tower Research Capital (TRC)
New York
$108K
Rockefeller Capital Management
105
Rockefeller Capital Management
New York
$94.6K
Russell Investments Group
106
Russell Investments Group
United Kingdom
$90.1K
Legal & General Group
107
Legal & General Group
United Kingdom
$80.1K
AIP
108
Ameritas Investment Partners
Nebraska
$72.9K
Mirae Asset Global Investments
109
Mirae Asset Global Investments
South Korea
$68.8K
Carson Wealth (CWM LLC)
110
Carson Wealth (CWM LLC)
Nebraska
$56K
California State Teachers Retirement System (CalSTRS)
111
California State Teachers Retirement System (CalSTRS)
California
$55.3K
SCM
112
Sterling Capital Management
North Carolina
$51.8K
Nisa Investment Advisors
113
Nisa Investment Advisors
Missouri
$50.2K
Royal Bank of Canada
114
Royal Bank of Canada
Ontario, Canada
$49K
AB
115
Amalgamated Bank
New York
$28K
GFM
116
GF Fund Management
China
$27.8K
SO
117
STRS Ohio
Ohio
$22.1K
US Bancorp
118
US Bancorp
Minnesota
$9.84K
GI
119
GAMMA Investing
California
$9.43K
ACM
120
Aster Capital Management
United Arab Emirates
$8.36K
PNC Financial Services Group
121
PNC Financial Services Group
Pennsylvania
$6.18K
S
122
SignatureFD
Georgia
$5.65K
Daiwa Securities Group
123
Daiwa Securities Group
Japan
$5K
PWA
124
Physician Wealth Advisors
Utah
$3.44K
UBS AM
125
UBS AM
Illinois
$3.15K