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Ligand Pharmaceuticals

271 hedge funds and large institutions have $2.18B invested in Ligand Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 33 funds opening new positions, 111 increasing their positions, 87 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

10,027% more call options, than puts

Call options by funds: $1.11M | Put options by funds: $11K

300% more funds holding in top 10

Funds holding in top 10: 14 (+3)

43% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 23

28% more repeat investments, than reductions

Existing positions increased: 111 | Existing positions reduced: 87

11% more capital invested

Capital invested by funds: $1.97B → $2.18B (+$211M)

3% more funds holding

Funds holding: 262271 (+9)

2.28% more ownership

Funds ownership: 97.22%99.5% (+2.3%)

Holders
271
Holders Change
+9
Holders Change %
+3.44%
% of All Funds
3.57%
Holding in Top 10
4
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+300%
% of All Funds
0.05%
New
33
Increased
111
Reduced
87
Closed
23
Calls
$1.11M
Puts
$11K
Net Calls
+$1.1M
Net Calls Change
+$964K
Name Holding Trade Value Shares
Change
Change in
Stake
VIA
151
Virtus Investment Advisers
Connecticut
$441K +$77.1K +721 +23%
CUAMC
152
China Universal Asset Management Company
China
$441K +$1.39K +13 +0.3%
US Bancorp
153
US Bancorp
Minnesota
$429K -$30.6K -286 -7%
EP
154
Edgestream Partners
New Jersey
$428K +$402K +3,765 New
JCM
155
Janney Capital Management
Pennsylvania
$419K -$51.3K -480 -12%
AAM
156
Advisors Asset Management
Colorado
$402K +$74.1K +693 +24%
CA
157
CWC Advisors
Oregon
$400K +$9.41K +88 +3%
PWG
158
Portside Wealth Group
Utah
$397K -$8.76K -82 -2%
MML Investors Services
159
MML Investors Services
Massachusetts
$397K +$37.5K +351 +11%
BCM
160
BTC Capital Management
Iowa
$389K +$35K +327 +11%
AQR Capital Management
161
AQR Capital Management
Connecticut
$382K +$2.46K +23 +0.7%
ETC
162
Exchange Traded Concepts
Oklahoma
$357K +$212K +1,987 +172%
TBC
163
Tweedy, Browne Co
Connecticut
$357K +$336K +3,140 New
Amundi
164
Amundi
France
$355K -$481K -4,500 -59%
SG Americas Securities
165
SG Americas Securities
New York
$351K -$398K -3,723 -55%
QC
166
Quadrature Capital
United Kingdom
$348K +$327K +3,056 New
CTC
167
Cetera Trust Company
Minnesota
$327K +$24K +225 +8%
CFO
168
Callan Family Office
Pennsylvania
$326K +$45.5K +426 +17%
State Board of Administration of Florida Retirement System
169
State Board of Administration of Florida Retirement System
Florida
$322K
Wealth Enhancement Advisory Services
170
Wealth Enhancement Advisory Services
Minnesota
$298K +$3.31K +31 +1%
Public Employees Retirement Association of Colorado
171
Public Employees Retirement Association of Colorado
Colorado
$290K
Zurich Cantonal Bank
172
Zurich Cantonal Bank
Switzerland
$285K -$1.28K -12 -0.5%
Los Angeles Capital Management
173
Los Angeles Capital Management
California
$282K -$6.52K -61 -2%
MOACM
174
Mutual of America Capital Management
New York
$282K -$29.2K -273 -10%
PA
175
Profund Advisors
Maryland
$277K -$3.96K -37 -1%

LGND Hedge Fund Activity: Q2 2025 in Review

271 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Ligand Pharmaceuticals (LGND) for Q2 2025, worth a combined $2.18B — up 11% from $1.97B a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new LGND positions and 23 closed out — a net gain of 10 holders — while 111 added to existing stakes and 87 trimmed.

The largest buyer was UBS AM, adding an estimated $36M. The largest seller was Castleark Management, exiting entirely with an estimated $6.99M sold.

  • 271 institutional investors held Ligand Pharmaceuticals (LGND) as of Q2 2025, up from 262 in Q1 2025.
  • Funds reported $2.18B of Ligand Pharmaceuticals stock for Q2 2025, up 11% quarter-over-quarter.
  • 33 funds opened new Ligand Pharmaceuticals positions in Q2 2025 and 23 closed out, a net change of +10 holders.
  • The largest Ligand Pharmaceuticals buyer in Q2 2025 was UBS AM, an estimated $36M added.
  • The largest Ligand Pharmaceuticals seller in Q2 2025 was Castleark Management, an estimated $6.99M sold.

Based on aggregated 13F filings for Q2 2025.