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Ligand Pharmaceuticals

271 hedge funds and large institutions have $2.18B invested in Ligand Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 33 funds opening new positions, 111 increasing their positions, 87 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

10,027% more call options, than puts

Call options by funds: $1.11M | Put options by funds: $11K

300% more funds holding in top 10

Funds holding in top 10: 14 (+3)

43% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 23

28% more repeat investments, than reductions

Existing positions increased: 111 | Existing positions reduced: 87

11% more capital invested

Capital invested by funds: $1.97B → $2.18B (+$211M)

3% more funds holding

Funds holding: 262271 (+9)

2.28% more ownership

Funds ownership: 97.22%99.5% (+2.3%)

Holders
271
Holders Change
+9
Holders Change %
+3.44%
% of All Funds
3.57%
Holding in Top 10
4
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+300%
% of All Funds
0.05%
New
33
Increased
111
Reduced
87
Closed
23
Calls
$1.11M
Puts
$11K
Net Calls
+$1.1M
Net Calls Change
+$964K
Name Holding Trade Value Shares
Change
Change in
Stake
Manulife (Manufacturers Life Insurance)
101
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.14M +$26.9K +252 +3%
CPC
102
Cookson Peirce & Co
Pennsylvania
$1.09M +$71.3K +667 +7%
Royal Bank of Canada
103
Royal Bank of Canada
Ontario, Canada
$1.07M +$357K +3,340 +55%
IMRF
104
Illinois Municipal Retirement Fund
Illinois
$1.03M -$180K -1,684 -16%
LSERS
105
Louisiana State Employees Retirement System
Louisiana
$1.02M +$10.7K +100 +1%
Ohio Public Employees Retirement System (OPERS)
106
Ohio Public Employees Retirement System (OPERS)
Ohio
$942K
William Blair & Company
107
William Blair & Company
Illinois
$875K -$164K -1,533 -17%
IIM
108
INTECH Investment Management
Florida
$873K -$183K -1,711 -18%
Comerica Bank
109
Comerica Bank
Texas
$869K +$28.5K +267 +4%
SO
110
STRS Ohio
Ohio
$841K -$10.7K -100 -1%
Wellington Management Group
111
Wellington Management Group
Massachusetts
$838K -$20.5K -192 -3%
MMEA
112
Main Management ETF Advisors
California
$833K +$12.8K +120 +2%
EA
113
Ellsworth Advisors
Ohio
$833K +$5.88K +55 +0.8%
GWM
114
Gibbs Wealth Management
Georgia
$831K +$105K +982 +16%
YCM
115
Yousif Capital Management
Michigan
$828K +$28.9K +270 +4%
D.E. Shaw & Co
116
D.E. Shaw & Co
New York
$813K +$764K +7,151 New
SMF
117
Scott Marsh Financial
Utah
$802K +$754K +7,051 New
EH
118
Equitable Holdings
New York
$797K +$156K +1,460 +26%
HC
119
Henshaw Capital
Massachusetts
$727K
Handelsbanken Fonder
120
Handelsbanken Fonder
Sweden
$723K -$32.1K -300 -5%
ET
121
Equitable Trust
Tennessee
$710K +$183K +1,710 +38%
SAM
122
Simplify Asset Management
Nevada
$679K -$69K -646 -10%
CC
123
Cornerstone Capital
California
$652K
Bank of Montreal
124
Bank of Montreal
Ontario, Canada
$651K +$15.7K +147 +3%
MSRPS
125
Maryland State Retirement & Pension System
Maryland
$645K +$16.1K +151 +3%

LGND Hedge Fund Activity: Q2 2025 in Review

271 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Ligand Pharmaceuticals (LGND) for Q2 2025, worth a combined $2.18B — up 11% from $1.97B a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new LGND positions and 23 closed out — a net gain of 10 holders — while 111 added to existing stakes and 87 trimmed.

The largest buyer was UBS AM, adding an estimated $36M. The largest seller was Castleark Management, exiting entirely with an estimated $6.99M sold.

  • 271 institutional investors held Ligand Pharmaceuticals (LGND) as of Q2 2025, up from 262 in Q1 2025.
  • Funds reported $2.18B of Ligand Pharmaceuticals stock for Q2 2025, up 11% quarter-over-quarter.
  • 33 funds opened new Ligand Pharmaceuticals positions in Q2 2025 and 23 closed out, a net change of +10 holders.
  • The largest Ligand Pharmaceuticals buyer in Q2 2025 was UBS AM, an estimated $36M added.
  • The largest Ligand Pharmaceuticals seller in Q2 2025 was Castleark Management, an estimated $6.99M sold.

Based on aggregated 13F filings for Q2 2025.