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Ligand Pharmaceuticals

357 hedge funds and large institutions have $4.15B invested in Ligand Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 59 funds opening new positions, 133 increasing their positions, 115 reducing their positions, and 43 closing their positions.

New
Increased
Maintained
Reduced
Closed

37% more first-time investments, than exits

New positions opened: 59 | Existing positions closed: 43

22% more call options, than puts

Call options by funds: $8.48M | Put options by funds: $6.95M

16% more repeat investments, than reductions

Existing positions increased: 133 | Existing positions reduced: 115

7% more capital invested

Capital invested by funds: $3.89B → $4.15B (+$264M)

2% more funds holding

Funds holding: 349357 (+8)

0% more funds holding in top 10

Funds holding in top 10: 88 (0)

0.18% less ownership

Funds ownership: 104.47%104.29% (-0.18%)

Holders
357
Holders Change
+8
Holders Change %
+2.29%
% of All Funds
4.39%
Holding in Top 10
8
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.1%
New
59
Increased
133
Reduced
115
Closed
43
Calls
$8.48M
Puts
$6.95M
Net Calls
+$1.54M
Net Calls Change
-$3.42M
Name Holding Trade Value Shares
Change
Change in
Stake
JP Morgan Chase
51
JP Morgan Chase
New York
$16.6M +$5.87M +29,684 +52%
First Trust Advisors
52
First Trust Advisors
Illinois
$16.1M +$2.21M +11,181 +16%
D.E. Shaw & Co
53
D.E. Shaw & Co
New York
$15.7M +$8.29M +41,877 +115%
Ameriprise
54
Ameriprise
Minnesota
$15.4M -$4.15M -20,991 -21%
SEI Investments
55
SEI Investments
Pennsylvania
$15M +$5.7M +28,820 +62%
Public Sector Pension Investment Board (PSP Investments)
56
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$14.1M +$448K +2,264 +3%
DIA
57
Dana Investment Advisors
Wisconsin
$13.8M -$32.1K -162 -0.2%
Prudential Financial
58
Prudential Financial
New Jersey
$12.8M +$3.66M +18,497 +41%
KCM
59
Kornitzer Capital Management
Kansas
$12M
Pictet Asset Management
60
Pictet Asset Management
Switzerland
$11.7M -$722K -3,649 -6%
EIM
61
Essex Investment Management
Massachusetts
$11.7M -$309K -1,560 -3%
Osaic Holdings
62
Osaic Holdings
Arizona
$11.6M -$248K -1,255 -2%
RhumbLine Advisers
63
RhumbLine Advisers
Massachusetts
$11.3M +$12.7K +64 +0.1%
GIP
64
Granite Investment Partners
California
$10.8M -$746K -3,771 -7%
Allspring Global Investments
65
Allspring Global Investments
North Carolina
$10.5M -$3.79M -19,166 -27%
Nordea Investment Management
66
Nordea Investment Management
Sweden
$9.83M -$552K -2,789 -5%
CM
67
Castleark Management
Illinois
$9.72M -$3.57M -18,040 -27%
Qube Research & Technologies (QRT)
68
Qube Research & Technologies (QRT)
United Kingdom
$9.52M +$6.38M +32,266 +210%
EIA
69
Emerald Investment Advisers
Pennsylvania
$8.83M +$8.75M +44,226 New
WCM Investment Management
70
WCM Investment Management
California
$8.6M -$191K -963 -2%
N
71
Nuveen
North Carolina
$8.52M +$1.01M +5,090 +14%
American Century Companies
72
American Century Companies
Missouri
$8.08M -$77.2K -390 -1%
UIC
73
Uniplan Investment Counsel
Wisconsin
$8.02M -$431K -2,179 -5%
Swiss National Bank
74
Swiss National Bank
Switzerland
$7.77M +$59.4K +300 +0.8%
LCG
75
Lisanti Capital Growth
New York
$7.71M -$1.01M -5,130 -12%

LGND Hedge Fund Activity: Q1 2026 in Review

357 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Ligand Pharmaceuticals (LGND) for Q1 2026, worth a combined $4.15B — up 6.8% from $3.89B a quarter earlier.

Buyers outnumbered sellers: 59 funds opened new LGND positions and 43 closed out — a net gain of 16 holders — while 133 added to existing stakes and 115 trimmed.

The largest buyer was Invesco, adding an estimated $60.8M. The largest seller was UBS AM, cutting an estimated $29.8M.

  • 357 institutional investors held Ligand Pharmaceuticals (LGND) as of Q1 2026, up from 349 in Q4 2025.
  • Funds reported $4.15B of Ligand Pharmaceuticals stock for Q1 2026, up 6.8% quarter-over-quarter.
  • 59 funds opened new Ligand Pharmaceuticals positions in Q1 2026 and 43 closed out, a net change of +16 holders.
  • The largest Ligand Pharmaceuticals buyer in Q1 2026 was Invesco, an estimated $60.8M added.
  • The largest Ligand Pharmaceuticals seller in Q1 2026 was UBS AM, an estimated $29.8M sold.

Based on aggregated 13F filings for Q1 2026.