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LBRX

LB Pharmaceuticals
LBRX

68 hedge funds and large institutions have $552M invested in LB Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 33 funds opening new positions, 13 increasing their positions, 12 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 1 → 3 (+2)

106% more first-time investments, than exits

New positions opened: 33 | Existing positions closed: 16

75% more capital invested

Capital invested by funds: $315M → $552M (+$237M)

28% more funds holding

Funds holding: 53 → 68 (+15)

8% more repeat investments, than reductions

Existing positions increased: 13 | Existing positions reduced: 12

1.19% less ownership

Funds ownership: 99.18% → 97.99% (-1.2%)

Holders
68
Holders Change
+15
Holders Change %
+28.3%
% of All Funds
0.83%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
33
Increased
13
Reduced
12
Closed
16
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
+$22.1M
2
Vanguard Group
Vanguard Group
Pennsylvania
+$19.4M
3
JP Morgan Chase
JP Morgan Chase
New York
+$10.1M
4
RCM
RA Capital Management
Massachusetts
+$7.54M
5
Geode Capital Management
Geode Capital Management
Massachusetts
+$7.47M

Top Sellers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
-$8.5M
2
SCM
Soleus Capital Management
Connecticut
-$6.81M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$5.44M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$4.74M
5
Marshall Wace
Marshall Wace
United Kingdom
-$4.15M
Name Holding Trade Value Shares
Change 		Change in
Stake
Mirae Asset Global ETFs Holdings
51
Mirae Asset Global ETFs Holdings
Hong Kong
$200K +$157K +8,966 New
SG Americas Securities
52
SG Americas Securities
New York
$143K +$112K +6,434 New
Federated Hermes
53
Federated Hermes
Pennsylvania
$111K -$69.9K -4,000 -44%
PFSRSONJ
54
Police & Firemen's Retirement System of New Jersey
New Jersey
$98.5K +$77.3K +4,425 New
PAP
55
Persistent Asset Partners
Hong Kong
$90.8K +$71.3K +4,080 New
BNP Paribas Financial Markets
56
BNP Paribas Financial Markets
France
$89.2K +$70K +4,007 New
SO
57
STRS Ohio
Ohio
$75.7K +$59.4K +3,400 New
Legal & General Group
58
Legal & General Group
United Kingdom
$41.8K +$32.8K +1,878 New
AIP
59
Ameritas Investment Partners
Nebraska
$34.8K +$27.3K +1,562 New
Russell Investments Group
60
Russell Investments Group
United Kingdom
$33.9K +$26.6K +1,525 New
TRCT
61
Tower Research Capital (TRC)
New York
$30.3K +$23.8K +1,361 New
California State Teachers Retirement System (CalSTRS)
62
California State Teachers Retirement System (CalSTRS)
California
$26.4K +$20.7K +1,184 New
Royal Bank of Canada
63
Royal Bank of Canada
Ontario, Canada
$17K +$13.4K +767 New
SCM
64
Sterling Capital Management
North Carolina
$13.2K +$10.3K +592 New
AB
65
Amalgamated Bank
New York
$13K +$10.6K +605 New
Citigroup
66
Citigroup
New York
$9.68K +$7.6K +435 New
GI
67
GAMMA Investing
California
$312 +$245 +14 New
Millennium Management
68
Millennium Management
New York
– -$8.5M -538,169 Closed
Wellington Management Group
69
Wellington Management Group
Massachusetts
– -$5.44M -344,657 Closed
Adage Capital Partners
70
Adage Capital Partners
Massachusetts
– -$3.16M -200,000 Closed
SCM
71
Silverarc Capital Management
Massachusetts
– -$1.11M -70,000 Closed
HF
72
HRT Financial
New York
– -$928K -58,815 Closed
MIM
73
Monashee Investment Management
Massachusetts
– -$632K -40,000 Closed
TD Asset Management
74
TD Asset Management
Ontario, Canada
– -$581K -36,780 Closed
Hudson Bay Capital Management
75
Hudson Bay Capital Management
Connecticut
– -$428K -27,097 Closed
1 2
3
4

LBRX Hedge Fund Activity: Q4 2025 in Review

68 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in LB Pharmaceuticals (LBRX) for Q4 2025, worth a combined $552M — up 75% from $315M a quarter earlier.

Buyers outnumbered sellers: 33 funds opened new LBRX positions and 16 closed out — a net gain of 17 holders — while 13 added to existing stakes and 12 trimmed.

The largest buyer was BlackRock, adding an estimated $22.1M. The largest seller was Millennium Management, exiting entirely with an estimated $8.5M sold.

  • 68 institutional investors held LB Pharmaceuticals (LBRX) as of Q4 2025, up from 53 in Q3 2025.
  • Funds reported $552M of LB Pharmaceuticals stock for Q4 2025, up 75% quarter-over-quarter.
  • 33 funds opened new LB Pharmaceuticals positions in Q4 2025 and 16 closed out, a net change of +17 holders.
  • The largest LB Pharmaceuticals buyer in Q4 2025 was BlackRock, an estimated $22.1M added.
  • The largest LB Pharmaceuticals seller in Q4 2025 was Millennium Management, an estimated $8.5M sold.

Based on aggregated 13F filings for Q4 2025.