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Kodiak Sciences
KOD

158 hedge funds and large institutions have $1.61B invested in Kodiak Sciences in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 50 increasing their positions, 40 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

292% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 13

150% more funds holding in top 10

Funds holding in top 10: 2 → 5 (+3)

145% more call options, than puts

Call options by funds: $7.99M | Put options by funds: $3.26M

121% more capital invested

Capital invested by funds: $728M → $1.61B (+$882M)

31% more funds holding

Funds holding: 121 → 158 (+37)

25% more repeat investments, than reductions

Existing positions increased: 50 | Existing positions reduced: 40

24.27% more ownership

Funds ownership: 84.25% → 108.53% (+24%)

Holders
158
Holders Change
+37
Holders Change %
+30.58%
% of All Funds
1.92%
Holding in Top 10
5
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+150%
% of All Funds
0.06%
New
51
Increased
50
Reduced
40
Closed
13
Calls
$7.99M
Puts
$3.26M
Net Calls
+$4.73M
Net Calls Change
+$3.45M

Top Buyers

1
BBA
Baker Bros. Advisors
New York
+$53.4M
2
B
Braidwell
Connecticut
+$42.4M
3
RI
RTW Investments
New York
+$30.5M
4
BlackRock
BlackRock
New York
+$20.5M
5
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$20.5M

Top Sellers

1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$13.7M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$11.3M
3
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$5.33M
4
NCM
Nantahala Capital Management
Connecticut
-$4.76M
5
BCM
Boone Capital Management
Georgia
-$4.34M
Name Holding Trade Value Shares
Change 		Change in
Stake
WWA
151
Wealth Watch Advisors
Colorado
$419 +$307 +15 New
RIL
152
Rothschild Investment LLC
Illinois
$391 +$287 +14 New
TWD
153
True Wealth Design
Ohio
$364 – – –
GRP
154
Global Retirement Partners
California
$280 +$82 +4 +67%
IA
155
IFP Advisors
Florida
$168 – – –
MCM
156
MAI Capital Management
Ohio
$140 +$102 +5 New
EP
157
Essential Partners
California
$112 +$82 +4 New
CIBC Private Wealth Group
158
CIBC Private Wealth Group
Georgia
$28 +$20 +1 New
NCM
159
Nantahala Capital Management
Connecticut
– -$4.76M -290,884 Closed
VPC
160
Vestal Point Capital
New York
– -$4.09M -250,000 Closed
FAM
161
Fred Alger Management
New York
– -$2.26M -138,303 Closed
Jane Street
162
Jane Street
New York
– -$2.59M -126,613 Closed
TCM
163
Tang Capital Management
California
– -$1.64M -100,000 Closed
GCP
164
GSA Capital Partners
United Kingdom
– -$1.44M -87,697 Closed
XT
165
XTX Topco
Cayman Islands
– -$411K -25,078 Closed
VF
166
Virtu Financial
New York
– -$394K -24,082 Closed
Optiver Holding
167
Optiver Holding
Netherlands
– -$8.3K -507 Closed
AAS
168
Ameritas Advisory Services
Nebraska
– -$8.19K -500 Closed
RA
169
Rise Advisors
New York
– -$5.83K -356 Closed
CIAM
170
Caitong International Asset Management
Hong Kong
– -$4.63K -283 Closed
AAP
171
Arax Advisory Partners
Colorado
– -$3.77K -230 Closed
3 4 5 6
7

KOD Hedge Fund Activity: Q4 2025 in Review

158 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Kodiak Sciences (KOD) for Q4 2025, worth a combined $1.61B — up 121% from $728M a quarter earlier.

Buyers outnumbered sellers: 51 funds opened new KOD positions and 13 closed out — a net gain of 38 holders — while 50 added to existing stakes and 40 trimmed.

The largest buyer was Baker Bros. Advisors, adding an estimated $53.4M. The largest seller was Point72 Asset Management, cutting an estimated $13.7M.

  • 158 institutional investors held Kodiak Sciences (KOD) as of Q4 2025, up from 121 in Q3 2025.
  • Funds reported $1.61B of Kodiak Sciences stock for Q4 2025, up 121% quarter-over-quarter.
  • 51 funds opened new Kodiak Sciences positions in Q4 2025 and 13 closed out, a net change of +38 holders.
  • The largest Kodiak Sciences buyer in Q4 2025 was Baker Bros. Advisors, an estimated $53.4M added.
  • The largest Kodiak Sciences seller in Q4 2025 was Point72 Asset Management, an estimated $13.7M sold.

Based on aggregated 13F filings for Q4 2025.