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Kodiak Sciences
KOD

158 hedge funds and large institutions have $1.61B invested in Kodiak Sciences in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 50 increasing their positions, 40 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

292% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 13

150% more funds holding in top 10

Funds holding in top 10: 2 → 5 (+3)

145% more call options, than puts

Call options by funds: $7.99M | Put options by funds: $3.26M

121% more capital invested

Capital invested by funds: $728M → $1.61B (+$882M)

31% more funds holding

Funds holding: 121 → 158 (+37)

25% more repeat investments, than reductions

Existing positions increased: 50 | Existing positions reduced: 40

24.27% more ownership

Funds ownership: 84.25% → 108.53% (+24%)

Holders
158
Holders Change
+37
Holders Change %
+30.58%
% of All Funds
1.92%
Holding in Top 10
5
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+150%
% of All Funds
0.06%
New
51
Increased
50
Reduced
40
Closed
13
Calls
$7.99M
Puts
$3.26M
Net Calls
+$4.73M
Net Calls Change
+$3.45M

Top Buyers

1
BBA
Baker Bros. Advisors
New York
+$53.4M
2
B
Braidwell
Connecticut
+$42.4M
3
RI
RTW Investments
New York
+$30.5M
4
BlackRock
BlackRock
New York
+$20.5M
5
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$20.5M

Top Sellers

1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$13.7M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$11.3M
3
Acadian Asset Management
Acadian Asset Management
Massachusetts
-$5.33M
4
NCM
Nantahala Capital Management
Connecticut
-$4.76M
5
BCM
Boone Capital Management
Georgia
-$4.34M
Name Holding Trade Value Shares
Change 		Change in
Stake
T. Rowe Price Investment Management
26
T. Rowe Price Investment Management
Maryland
$11.4M +$8.38M +409,126 New
Renaissance Technologies
27
Renaissance Technologies
New York
$10.1M -$2.08M -101,500 -22%
Charles Schwab
28
Charles Schwab
California
$9.52M +$1.25M +61,176 +22%
Northern Trust
29
Northern Trust
Illinois
$9.33M -$86.7K -4,236 -1%
Dimensional Fund Advisors
30
Dimensional Fund Advisors
Texas
$9.16M -$3.9M -190,518 -37%
D.E. Shaw & Co
31
D.E. Shaw & Co
New York
$8.97M -$2.81M -137,209 -30%
SCM
32
Squadron Capital Management
Illinois
$8.16M +$5.97M +291,710 New
Citadel Advisors
33
Citadel Advisors
Florida
$8.12M +$5.02M +245,024 +539%
JG
34
Jain Global
New York
$7.97M +$5.83M +284,899 New
Balyasny Asset Management
35
Balyasny Asset Management
Illinois
$7.36M +$5.08M +247,859 +1,607%
Federated Hermes
36
Federated Hermes
Pennsylvania
$6.83M – – –
AI
37
Atom Investors
Texas
$5.8M +$4.25M +207,495 New
Fidelity Investments
38
Fidelity Investments
Massachusetts
$5.57M -$1.31M -63,863 -24%
Bank of America
39
Bank of America
North Carolina
$5.5M -$2.3M -112,382 -36%
TI
40
Trexquant Investment
Connecticut
$5.33M +$2.93M +143,250 +303%
PAM
41
Panagora Asset Management
Massachusetts
$5.05M +$529K +25,813 +17%
SFM
42
Sphera Funds Management
Israel
$4.91M +$3.59M +175,500 New
BFM
43
Boothbay Fund Management
New York
$4.84M +$1.16M +56,786 +49%
UBS Group
44
UBS Group
Switzerland
$4.71M +$2.29M +111,853 +197%
BC
45
Bruce & Co
Illinois
$4.61M -$2.34M -114,308 -41%
TD Asset Management
46
TD Asset Management
Ontario, Canada
$3.74M +$1.5M +73,318 +121%
Jacobs Levy Equity Management
47
Jacobs Levy Equity Management
New Jersey
$3.56M -$778K -37,990 -23%
Barclays
48
Barclays
United Kingdom
$3.48M +$1.14M +55,485 +81%
RAG
49
RIA Advisory Group
Iowa
$3.17M -$1.07M -52,061 -31%
Two Sigma Advisers
50
Two Sigma Advisers
New York
$2.88M -$2.18M -106,300 -51%
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KOD Hedge Fund Activity: Q4 2025 in Review

158 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Kodiak Sciences (KOD) for Q4 2025, worth a combined $1.61B — up 121% from $728M a quarter earlier.

Buyers outnumbered sellers: 51 funds opened new KOD positions and 13 closed out — a net gain of 38 holders — while 50 added to existing stakes and 40 trimmed.

The largest buyer was Baker Bros. Advisors, adding an estimated $53.4M. The largest seller was Point72 Asset Management, cutting an estimated $13.7M.

  • 158 institutional investors held Kodiak Sciences (KOD) as of Q4 2025, up from 121 in Q3 2025.
  • Funds reported $1.61B of Kodiak Sciences stock for Q4 2025, up 121% quarter-over-quarter.
  • 51 funds opened new Kodiak Sciences positions in Q4 2025 and 13 closed out, a net change of +38 holders.
  • The largest Kodiak Sciences buyer in Q4 2025 was Baker Bros. Advisors, an estimated $53.4M added.
  • The largest Kodiak Sciences seller in Q4 2025 was Point72 Asset Management, an estimated $13.7M sold.

Based on aggregated 13F filings for Q4 2025.