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Incyte
INCY

712 hedge funds and large institutions have $16.8B invested in Incyte in 2025 Q3 according to their latest regulatory filings, with 126 funds opening new positions, 261 increasing their positions, 236 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more first-time investments, than exits

New positions opened: 126 | Existing positions closed: 63

26% more capital invested

Capital invested by funds: $13.4B → $16.8B (+$3.42B)

11% more repeat investments, than reductions

Existing positions increased: 261 | Existing positions reduced: 236

8% more funds holding

Funds holding: 657 → 712 (+55)

5% more call options, than puts

Call options by funds: $59.1M | Put options by funds: $56.5M

0% less ownership

Funds ownership: 101.61% → 101.61% (-0%)

14% less funds holding in top 10

Funds holding in top 10: 7 → 6 (-1)

Holders
712
Holders Change
+55
Holders Change %
+8.37%
% of All Funds
9.35%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
126
Increased
261
Reduced
236
Closed
63
Calls
$59.1M
Puts
$56.5M
Net Calls
+$2.62M
Net Calls Change
-$14.7M

Top Buyers

1
Los Angeles Capital Management
Los Angeles Capital Management
California
+$114M
2
Pacer Advisors
Pacer Advisors
Pennsylvania
+$97.5M
3
Caisse de Depot et Placement du Quebec (CDPQ)
Caisse de Depot et Placement du Quebec (CDPQ)
Quebec, Canada
+$85.9M
4
Royal Bank of Canada
Royal Bank of Canada
Ontario, Canada
+$83.6M
5
Renaissance Technologies
Renaissance Technologies
New York
+$51.1M

Top Sellers

1
Marshall Wace
Marshall Wace
United Kingdom
-$94.5M
2
SG Americas Securities
SG Americas Securities
New York
-$73M
3
Dodge & Cox
Dodge & Cox
California
-$52.4M
4
JAM
Jupiter Asset Management
United Kingdom
-$46.7M
5
Squarepoint
Squarepoint
New York
-$43.8M
Name Holding Trade Value Shares
Change 		Change in
Stake
TSS
726
Two Sigma Securities
New York
– -$1.93M -28,292 Closed
NRD
727
Nebula Research & Development
New York
– -$1.44M -21,089 Closed
FRM
728
Fox Run Management
Connecticut
– -$1.06M -15,623 Closed
MC
729
Machina Capital
France
– -$787K -11,557 Closed
SA
730
Sovran Advisors
California
– -$778K -11,504 Closed
CIM
731
Contravisory Investment Management
Massachusetts
– -$772K -11,338 Closed
SPS
732
Susquehanna Portfolio Strategies
Pennsylvania
– -$740K -10,860 Closed
BFM
733
Boothbay Fund Management
New York
– -$686K -10,070 Closed
GI
734
GS Investments
Minnesota
– -$681K -10,000 Closed
DFCM
735
Dark Forest Capital Management
Puerto Rico
– -$582K -8,552 Closed
PD
736
Point72 (DIFC)
United Arab Emirates
– -$570K -8,367 Closed
AC
737
AXQ Capital
New Jersey
– -$532K -7,815 Closed
BC
738
Bridgefront Capital
Texas
– -$470K -6,907 Closed
AG
739
Algert Global
California
– -$460K -6,760 Closed
GWM
740
GDS Wealth Management
Texas
– -$449K -6,587 Closed
FC
741
Farringdon Capital
United Kingdom
– -$445K -6,533 Closed
CF
742
Cantor Fitzgerald
New York
– -$514K -6,500 Closed
IFU
743
iSAM Funds (UK)
United Kingdom
– -$431K -6,333 Closed
VSQM
744
V-Square Quantitative Management
Illinois
– -$422K -6,193 Closed
QCM
745
Qsemble Capital Management
New York
– -$393K -5,767 Closed
JG
746
Jain Global
New York
– -$371K -5,452 Closed
QC
747
Quadrature Capital
United Kingdom
– -$363K -5,330 Closed
MPM
748
MBB Public Markets
Illinois
– -$293K -4,298 Closed
BCP
749
Blackhawk Capital Partners
Wisconsin
– -$277K -4,062 Closed
CBUSF
750
Construction & Building Unions Superannuation Fund
Australia
– -$211K -3,100 Closed
27 28 29
30
31

INCY Hedge Fund Activity: Q3 2025 in Review

712 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Incyte (INCY) for Q3 2025, worth a combined $16.8B — up 26% from $13.4B a quarter earlier.

Buyers outnumbered sellers: 126 funds opened new INCY positions and 63 closed out — a net gain of 63 holders — while 261 added to existing stakes and 236 trimmed.

The largest buyer was Los Angeles Capital Management, adding an estimated $114M. The largest seller was Marshall Wace, cutting an estimated $94.5M.

  • 712 institutional investors held Incyte (INCY) as of Q3 2025, up from 657 in Q2 2025.
  • Funds reported $16.8B of Incyte stock for Q3 2025, up 26% quarter-over-quarter.
  • 126 funds opened new Incyte positions in Q3 2025 and 63 closed out, a net change of +63 holders.
  • The largest Incyte buyer in Q3 2025 was Los Angeles Capital Management, an estimated $114M added.
  • The largest Incyte seller in Q3 2025 was Marshall Wace, an estimated $94.5M sold.

Based on aggregated 13F filings for Q3 2025.