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iShares US Pharmaceuticals ETF
IHE

178 hedge funds and large institutions have $551M invested in iShares US Pharmaceuticals ETF in 2025 Q4 according to their latest regulatory filings, with 45 funds opening new positions, 61 increasing their positions, 26 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

246% more first-time investments, than exits

New positions opened: 45 | Existing positions closed: 13

135% more repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 26

61% more capital invested

Capital invested by funds: $342M → $551M (+$208M)

19% more funds holding

Funds holding: 149 → 178 (+29)

6.65% more ownership

Funds ownership: 58.27% → 64.92% (+6.6%)

Holders
178
Holders Change
+29
Holders Change %
+19.46%
% of All Funds
2.16%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
% of All Funds
0.01%
New
45
Increased
61
Reduced
26
Closed
13
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
FIA
Foundations Investment Advisors
Arizona
+$51.3M
2
Bank of America
Bank of America
North Carolina
+$26.3M
3
Morgan Stanley
Morgan Stanley
New York
+$22.7M
4
ACM
Anfield Capital Management
California
+$9.41M
5
JP Morgan Chase
JP Morgan Chase
New York
+$8.02M

Top Sellers

1
Goldman Sachs
Goldman Sachs
New York
-$5.02M
2
Fisher Asset Management
Fisher Asset Management
Washington
-$4.84M
3
Jane Street
Jane Street
New York
-$981K
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$968K
5
TRCT
Tower Research Capital (TRC)
New York
-$592K
Name Holding Trade Value Shares
Change 		Change in
Stake
Mariner
26
Mariner
Kansas
$2.15M -$85.3K -1,069 -4%
BCV
27
Banque Cantonale Vaudoise
Switzerland
$2.08M +$1.96M +24,500 New
VA
28
VestGen Advisors
Illinois
$2M +$1.88M +23,549 New
Bank of Montreal
29
Bank of Montreal
Ontario, Canada
$1.91M +$382K +4,781 +27%
GC
30
Grimes & Company
Massachusetts
$1.9M +$74.1K +929 +4%
Citadel Advisors
31
Citadel Advisors
Florida
$1.81M +$1.16M +14,557 +213%
CFA
32
Cahill Financial Advisors
Minnesota
$1.72M +$4.39K +55 +0.3%
DADC
33
D.A. Davidson & Co
Montana
$1.71M +$1.61M +20,148 New
ST
34
Spinnaker Trust
Maine
$1.34M -$184K -2,305 -13%
OCM
35
One Capital Management
California
$1.29M -$139K -1,742 -10%
MWM
36
Massachusetts Wealth Management
Massachusetts
$1.29M -$19.6K -245 -2%
Fidelity Investments
37
Fidelity Investments
Massachusetts
$1.25M +$151K +1,890 +15%
Jones Financial Companies
38
Jones Financial Companies
Missouri
$1.25M -$374K -4,684 -24%
Marshall Wace
39
Marshall Wace
United Kingdom
$1.22M +$1.14M +14,338 New
Cetera Investment Advisers
40
Cetera Investment Advisers
Illinois
$1.2M +$82.9K +1,039 +8%
Corient Private Wealth
41
Corient Private Wealth
Florida
$1.1M +$535K +6,704 +106%
AMG
42
Asset Management Group
Connecticut
$1.1M +$7.02K +88 +0.7%
TYCC
43
Texas Yale Capital Corp
Florida
$1.04M – – –
CCA
44
Childress Capital Advisors
Texas
$1.02M +$958K +12,000 New
IFWM
45
Institute for Wealth Management
Colorado
$956K +$56.5K +708 +7%
Janney Montgomery Scott
46
Janney Montgomery Scott
Pennsylvania
$882K +$292K +3,656 +54%
HighTower Advisors
47
HighTower Advisors
Illinois
$770K -$15.8K -198 -2%
AWM
48
Axxcess Wealth Management
California
$769K +$157K +1,968 +28%
Truist Financial
49
Truist Financial
North Carolina
$731K -$20K -251 -3%
Stifel Financial
50
Stifel Financial
Missouri
$718K -$1.92K -24 -0.3%
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IHE Hedge Fund Activity: Q4 2025 in Review

178 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in iShares US Pharmaceuticals ETF (IHE) for Q4 2025, worth a combined $551M — up 61% from $342M a quarter earlier.

Buyers outnumbered sellers: 45 funds opened new IHE positions and 13 closed out — a net gain of 32 holders — while 61 added to existing stakes and 26 trimmed.

The largest buyer was Foundations Investment Advisors, opening a new position worth an estimated $51.3M. The largest seller was Goldman Sachs, cutting an estimated $5.02M.

  • 178 institutional investors held iShares US Pharmaceuticals ETF (IHE) as of Q4 2025, up from 149 in Q3 2025.
  • Funds reported $551M of iShares US Pharmaceuticals ETF stock for Q4 2025, up 61% quarter-over-quarter.
  • 45 funds opened new iShares US Pharmaceuticals ETF positions in Q4 2025 and 13 closed out, a net change of +32 holders.
  • The largest iShares US Pharmaceuticals ETF buyer in Q4 2025 was Foundations Investment Advisors, an estimated $51.3M added.
  • The largest iShares US Pharmaceuticals ETF seller in Q4 2025 was Goldman Sachs, an estimated $5.02M sold.

Based on aggregated 13F filings for Q4 2025.