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Humacyte

141 hedge funds and large institutions have $79.8M invested in Humacyte in 2025 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 39 increasing their positions, 46 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

7.84% less ownership

Funds ownership: 36.69%28.85% (-7.8%)

10% less funds holding

Funds holding: 156141 (-15)

15% less repeat investments, than reductions

Existing positions increased: 39 | Existing positions reduced: 46

22% less call options, than puts

Call options by funds: $1M | Put options by funds: $1.28M

33% less capital invested

Capital invested by funds: $119M → $79.8M (-$39.1M)

45% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 29

Holders
141
Holders Change
-15
Holders Change %
-9.62%
% of All Funds
1.85%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
16
Increased
39
Reduced
46
Closed
29
Calls
$1M
Puts
$1.28M
Net Calls
-$284K
Net Calls Change
-$19K
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Advisers
26
Two Sigma Advisers
New York
$423K -$243K -124,000 -34%
WE
27
Wealth Effects
Massachusetts
$362K +$207K +105,850 +104%
XT
28
XTX Topco
Cayman Islands
$337K -$191K -97,266 -33%
UAS
29
United Asset Strategies
New York
$321K
Barclays
30
Barclays
United Kingdom
$318K -$509K -260,001 -59%
RhumbLine Advisers
31
RhumbLine Advisers
Massachusetts
$305K -$4.2K -2,144 -1%
BCM
32
Bridgeway Capital Management
Texas
$305K
AllianceBernstein
33
AllianceBernstein
Tennessee
$253K
Group One Trading
34
Group One Trading
Illinois
$243K +$171K +87,493 +168%
TC
35
Trilogy Capital
California
$226K
EWM
36
Endowment Wealth Management
Wisconsin
$190K
Deutsche Bank
37
Deutsche Bank
Germany
$176K +$24K +12,258 +14%
Wells Fargo
38
Wells Fargo
California
$171K +$31.8K +16,213 +20%
Jane Street
39
Jane Street
New York
$167K +$75.5K +38,560 +67%
BNP Paribas Financial Markets
40
BNP Paribas Financial Markets
France
$160K +$83.7K +42,701 +87%
IAN
41
Integrated Advisors Network
Texas
$151K +$170K +86,782 New
LPC
42
Lion Point Capital
New York
$145K
BHCM
43
Brevan Howard Capital Management
Jersey
$140K -$93K -47,464 -37%
Raymond James Financial
44
Raymond James Financial
Florida
$126K +$120K +61,017 +549%
Cetera Investment Advisers
45
Cetera Investment Advisers
Illinois
$123K +$75K +38,300 +119%
Osaic Holdings
46
Osaic Holdings
Arizona
$122K -$37.9K -19,350 -21%
LSIA
47
LaSalle St. Investment Advisors
Illinois
$117K +$13.4K +6,823 +11%
QOP
48
Quinn Opportunity Partners
Virginia
$113K
JP Morgan Chase
49
JP Morgan Chase
New York
$112K -$11.6K -5,905 -8%
T. Rowe Price Associates
50
T. Rowe Price Associates
Maryland
$110K

HUMA Hedge Fund Activity: Q3 2025 in Review

141 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Humacyte (HUMA) for Q3 2025, worth a combined $79.8M — down 33% from $119M a quarter earlier.

Sellers outnumbered buyers: 29 funds closed out of HUMA and 16 opened new positions — a net loss of 13 holders — while 46 trimmed existing stakes and 39 added.

The largest buyer was Morgan Stanley, adding an estimated $1.41M. The largest seller was CenterBook Partners, cutting an estimated $6.16M.

  • 141 institutional investors held Humacyte (HUMA) as of Q3 2025, down from 156 in Q2 2025.
  • Funds reported $79.8M of Humacyte stock for Q3 2025, down 33% quarter-over-quarter.
  • 16 funds opened new Humacyte positions in Q3 2025 and 29 closed out, a net change of -13 holders.
  • The largest Humacyte buyer in Q3 2025 was Morgan Stanley, an estimated $1.41M added.
  • The largest Humacyte seller in Q3 2025 was CenterBook Partners, an estimated $6.16M sold.

Based on aggregated 13F filings for Q3 2025.