Generation Bio
GBIO
GBIO was delisted on the 6th of February, 2026.
79 hedge funds and large institutions have $19.3M invested in Generation Bio in 2025 Q1 according to their latest regulatory filings, with 9 funds opening new positions, 15 increasing their positions, 37 reducing their positions, and 8 closing their positions.
13% more first-time investments, than exits
New positions opened: 9 | Existing positions closed: 8
1% more funds holding
Funds holding: 78 → 79 (+1)
0.94% less ownership
Funds ownership: 8.06% → 7.12% (-0.94%)
59% less repeat investments, than reductions
Existing positions increased: 15 | Existing positions reduced: 37
66% less capital invested
Capital invested by funds: $57.1M → $19.3M (-$37.8M)
100% less funds holding in top 10
Funds holding in top 10: 1 → 0 (-1)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Renaissance Technologies
New York
|
+$645K |
| 2 |
Acadian Asset Management
Boston,
Massachusetts
|
+$287K |
| 3 |
Squarepoint
New York
|
+$263K |
| 4 |
Los Angeles Capital Management
Los Angeles,
California
|
+$93.4K |
| 5 |
Fidelity Investments
Boston,
Massachusetts
|
+$88.8K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
EC
EcoR1 Capital
San Francisco,
California
|
-$2.17M |
| 2 |
JFG
Jefferies Financial Group
New York
|
-$1.47M |
| 3 |
Bank of America
Charlotte,
North Carolina
|
-$1.2M |
| 4 |
PHS
PFM Health Sciences
San Francisco,
California
|
-$835K |
| 5 |
D.E. Shaw & Co
New York
|
-$366K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
CA
76
CoreCap Advisors
Southfield,
Michigan
| $383 | +$372 | +53 | +126% |
|
|
SS
77
SBI Securities
Tokyo,
Japan
| $190 | – | – | – |
|
|
TWD
78
True Wealth Design
Akron,
Ohio
| $53 | +$91 | +13 | New |
|
|
EWA
79
EverSource Wealth Advisors
Birmingham,
Alabama
| $11 | -$35 | -5 | -63% |
|
|
FHA
80
First Horizon Advisors
Memphis,
Tennessee
| $1 | – | – | – |
|
|
EC
81
EcoR1 Capital
San Francisco,
California
| – | -$2.17M | -204,687 | Closed |
|
|
PHS
82
PFM Health Sciences
San Francisco,
California
| – | -$835K | -78,791 | Closed |
|
|
83
D.E. Shaw & Co
New York
| – | -$366K | -34,492 | Closed |
|
84
Millennium Management
New York
| – | -$97.1K | -9,158 | Closed |
|
85
Connor, Clark & Lunn Investment Management (CC&L)
Vancouver,
British Columbia, Canada
| – | -$67.4K | -6,356 | Closed |
|
86
Envestnet Asset Management
Chicago,
Illinois
| – | -$14.9K | -1,410 | Closed |
|
87
VOYA Investment Management
Atlanta,
Georgia
| – | -$12.4K | -1,169 | Closed |
|
88
AssetMark Inc
Concord,
California
| – | -$106 | -10 | Closed |
|
GBIO Hedge Fund Activity: Q1 2025 in Review
79 of the 7,463 institutional investors tracked by Wall St. Rank reported a position in Generation Bio (GBIO) for Q1 2025, worth a combined $19.3M — down 66% from $57.1M a quarter earlier.
Buyers outnumbered sellers: 9 funds opened new GBIO positions and 8 closed out — a net gain of 1 holder — while 15 added to existing stakes and 37 trimmed.
The largest buyer was Renaissance Technologies, adding an estimated $645K. The largest seller was EcoR1 Capital, exiting entirely with an estimated $2.17M sold.
- 79 institutional investors held Generation Bio (GBIO) as of Q1 2025, up from 78 in Q4 2024.
- Funds reported $19.3M of Generation Bio stock for Q1 2025, down 66% quarter-over-quarter.
- 9 funds opened new Generation Bio positions in Q1 2025 and 8 closed out, a net change of +1 holder.
- The largest Generation Bio buyer in Q1 2025 was Renaissance Technologies, an estimated $645K added.
- The largest Generation Bio seller in Q1 2025 was EcoR1 Capital, an estimated $2.17M sold.
Based on aggregated 13F filings for Q1 2025.