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Dianthus Therapeutics

241 hedge funds and large institutions have $5.36B invested in Dianthus Therapeutics in 2026 Q1 according to their latest regulatory filings, with 98 funds opening new positions, 83 increasing their positions, 54 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

416% more first-time investments, than exits

New positions opened: 98 | Existing positions closed: 19

165% more capital invested

Capital invested by funds: $2.02B → $5.36B (+$3.34B)

100% more funds holding in top 10

Funds holding in top 10: 816 (+8)

54% more repeat investments, than reductions

Existing positions increased: 83 | Existing positions reduced: 54

46% more funds holding

Funds holding: 165241 (+76)

30.04% more ownership

Funds ownership: 114.56%144.59% (+30%)

12% less call options, than puts

Call options by funds: $19.7M | Put options by funds: $22.3M

Holders
241
Holders Change
+76
Holders Change %
+46.06%
% of All Funds
2.97%
Holding in Top 10
16
Holding in Top 10 Change
+8
Holding in Top 10 Change %
+100%
% of All Funds
0.2%
New
98
Increased
83
Reduced
54
Closed
19
Calls
$19.7M
Puts
$22.3M
Net Calls
-$2.66M
Net Calls Change
-$680K
Name Holding Trade Value Shares
Change
Change in
Stake
Point72 Asset Management
26
Point72 Asset Management
Connecticut
$54M -$30.3M -522,489 -45%
CCM
27
Catalio Capital Management
New York
$47M -$5.4M -93,264 -14%
Goldman Sachs
28
Goldman Sachs
New York
$46M -$1.68M -29,009 -5%
Jennison Associates
29
Jennison Associates
New York
$40.7M +$28.1M +485,136 New
Balyasny Asset Management
30
Balyasny Asset Management
Illinois
$39.8M +$27.5M +474,085 New
AllianceBernstein
31
AllianceBernstein
Tennessee
$38.2M +$5.31M +91,688 +11%
WP
32
Woodline Partners
California
$36.4M +$12.8M +220,370 +103%
SC
33
Samlyn Capital
New York
$36.2M +$25M +431,115 New
Ameriprise
34
Ameriprise
Minnesota
$36M +$15.9M +273,964 +177%
MB
35
MPM BioImpact
Massachusetts
$35.6M +$24.6M +423,982 New
LGM
36
Logos Global Management
California
$33.6M +$4.92M +85,000 +27%
Artisan Partners
37
Artisan Partners
Wisconsin
$32.1M +$22.1M +382,121 New
Barclays
38
Barclays
United Kingdom
$31.9M +$11.8M +203,306 +115%
SSC
39
Spruce Street Capital
New York
$31.3M +$4.39M +75,837 +25%
SCM
40
Sio Capital Management
New York
$31.1M -$6.05M -104,458 -22%
BCLSI
41
Bain Capital Life Sciences Investors
Massachusetts
$30.4M -$22.1M -381,122 -51%
VC
42
Vivo Capital
California
$29.7M
AAA
43
Affinity Asset Advisors
New York
$29.4M +$13.6M +235,000 +204%
VPM
44
Vanguard Portfolio Management
Pennsylvania
$29.3M +$20.2M +349,381 New
Marshall Wace
45
Marshall Wace
United Kingdom
$28.7M -$38.6M -666,604 -66%
Dimensional Fund Advisors
46
Dimensional Fund Advisors
Texas
$27.3M +$6.65M +114,767 +54%
DCM
47
Driehaus Capital Management
Illinois
$26.6M +$18.4M +317,312 New
Charles Schwab
48
Charles Schwab
California
$25.6M +$3.16M +54,628 +22%
Northern Trust
49
Northern Trust
Illinois
$25.5M +$5.59M +96,506 +47%
Lord, Abbett & Co
50
Lord, Abbett & Co
New Jersey
$25.1M +$17.3M +299,210 New

DNTH Hedge Fund Activity: Q1 2026 in Review

241 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Dianthus Therapeutics (DNTH) for Q1 2026, worth a combined $5.36B — up 165% from $2.02B a quarter earlier.

Buyers outnumbered sellers: 98 funds opened new DNTH positions and 19 closed out — a net gain of 79 holders — while 83 added to existing stakes and 54 trimmed.

The largest buyer was Avidity Partners Management, adding an estimated $122M. The largest seller was Marshall Wace, cutting an estimated $38.6M.

  • 241 institutional investors held Dianthus Therapeutics (DNTH) as of Q1 2026, up from 165 in Q4 2025.
  • Funds reported $5.36B of Dianthus Therapeutics stock for Q1 2026, up 165% quarter-over-quarter.
  • 98 funds opened new Dianthus Therapeutics positions in Q1 2026 and 19 closed out, a net change of +79 holders.
  • The largest Dianthus Therapeutics buyer in Q1 2026 was Avidity Partners Management, an estimated $122M added.
  • The largest Dianthus Therapeutics seller in Q1 2026 was Marshall Wace, an estimated $38.6M sold.

Based on aggregated 13F filings for Q1 2026.