CARGO TherapeuticsCRGX
About: Cargo Therapeutics Inc is a clinical-stage biotechnology company positioned to advance next generation, potentially curative cell therapies for cancer patients. It programs, platforms, and manufacturing are designed to directly address the limitations of approved chimeric antigen receptor (CAR) T-cell therapies. Its product includes CRG-023, an investigational tri-specific CAR T designed to address several known causes of relapse associated with existing CAR T-cell therapies such as loss of tumor antigen expression, loss of co-stimulation (e.g., via CD58/CD2 signaling) and T cell exhaustion. CRG-023 is designed to target the B-cell lineage antigens (CD19, CD20, CD22) via tri-cistronic expression of three distinct CARs from a single lentiviral vector.
Employees: 167
Fund manager confidence
Based on 2024 Q4 regulatory disclosures by fund managers ($100M+ AUM)
400% more first-time investments, than exits
New positions opened: 25 | Existing positions closed: 5
124% more repeat investments, than reductions
Existing positions increased: 38 | Existing positions reduced: 17
75% more funds holding in top 10
Funds holding in top 10: 4 [Q3] → 7 (+3) [Q4]
25% more funds holding
Funds holding: 79 [Q3] → 99 (+20) [Q4]
15.75% more ownership
Funds ownership: 101.95% [Q3] → 117.7% (+15.75%) [Q4]
10% less capital invested
Capital invested by funds: $865M [Q3] → $781M (-$83.9M) [Q4]
Research analyst outlook
We haven’t received any recent analyst ratings for CRGX.
Financial journalist opinion









