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CNTA

Centessa Pharmaceuticals
CNTA

Delisted

CNTA was delisted on the 23rd of June, 2026.

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146 hedge funds and large institutions have $3.6B invested in Centessa Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 43 funds opening new positions, 48 increasing their positions, 44 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

115% more first-time investments, than exits

New positions opened: 43 | Existing positions closed: 20

60% more call options, than puts

Call options by funds: $10.5M | Put options by funds: $6.52M

17% more funds holding

Funds holding: 125 → 146 (+21)

16% more capital invested

Capital invested by funds: $3.11B → $3.6B (+$483M)

11.11% more ownership

Funds ownership: 95.83% → 106.95% (+11%)

9% more funds holding in top 10

Funds holding in top 10: 11 → 12 (+1)

9% more repeat investments, than reductions

Existing positions increased: 48 | Existing positions reduced: 44

Holders
146
Holders Change
+21
Holders Change %
+16.8%
% of All Funds
1.77%
Holding in Top 10
12
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+9.09%
% of All Funds
0.15%
New
43
Increased
48
Reduced
44
Closed
20
Calls
$10.5M
Puts
$6.52M
Net Calls
+$3.93M
Net Calls Change
-$6.66M

Top Buyers

Rank Fund Capital Flow
1
ACA
Avoro Capital Advisors
New York
+$94.9M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$68M
3
EC
EcoR1 Capital
California
+$65M
4
B
Braidwell
Connecticut
+$55.4M
5
DTC
Deep Track Capital
Connecticut
+$50.7M

Top Sellers

Rank Fund Capital Flow
1
GA
General Atlantic
New York
-$90.3M
2
CC
Commodore Capital
New York
-$46.9M
3
FLAM
First Light Asset Management
Minnesota
-$34.4M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$33.3M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
-$26M
Name Holding Trade Value Shares
Change 		Change in
Stake
Verition Fund Management
76
Verition Fund Management
Connecticut
$2.37M -$491K -19,394 -17%
DP
77
Diadema Partners
New Jersey
$2.25M +$2.28M +90,000 New
Geode Capital Management
78
Geode Capital Management
Massachusetts
$2.19M -$188K -7,422 -8%
Squarepoint
79
Squarepoint
New York
$2.05M +$1.58M +62,399 +321%
DZ Bank
80
DZ Bank
Germany
$2.04M -$883K -34,872 -30%
JP Morgan Chase
81
JP Morgan Chase
New York
$2.04M -$4.06M -160,409 -66%
XT
82
XTX Topco
Cayman Islands
$1.98M +$2M +79,077 New
VCM
83
Voleon Capital Management
California
$1.98M +$2M +79,074 New
SSC
84
Spruce Street Capital
New York
$1.95M +$1.98M +77,997 New
Russell Investments Group
85
Russell Investments Group
United Kingdom
$1.87M -$2.72M -107,481 -59%
CCM
86
Cinctive Capital Management
New York
$1.82M -$501K -19,797 -21%
ACM
87
Aquatic Capital Management
Illinois
$1.74M +$1.77M +69,755 New
Two Sigma Investments
88
Two Sigma Investments
New York
$1.44M – – –
Wellington Management Group
89
Wellington Management Group
Massachusetts
$1.26M -$823K -32,485 -39%
SGM
90
Seven Grand Managers
New York
$1.25M +$1.27M +50,000 New
HS
91
HighVista Strategies
Massachusetts
$1.11M -$476K -18,811 -30%
PAP
92
Persistent Asset Partners
Hong Kong
$1.08M +$1.1M +43,266 New
ACM
93
ADAR1 Capital Management
Texas
$965K -$382K -15,100 -28%
BMSSC
94
B. Metzler seel. Sohn & Co
Germany
$961K +$973K +38,432 New
GCP
95
GSA Capital Partners
United Kingdom
$828K +$363K +14,343 +76%
BFM
96
Boothbay Fund Management
New York
$813K +$283K +11,189 +52%
VOYA Investment Management
97
VOYA Investment Management
Georgia
$742K – – –
PR
98
PSP Research
Pennsylvania
$547K +$554K +21,879 New
AI
99
Atom Investors
Texas
$459K +$465K +18,347 New
MWP
100
Meridian Wealth Partners
Pennsylvania
$453K – – –
2 3
4
5 6

CNTA Hedge Fund Activity: Q4 2025 in Review

146 of the 8,243 institutional investors tracked by Wall St. Rank reported a position in Centessa Pharmaceuticals (CNTA) for Q4 2025, worth a combined $3.6B — up 16% from $3.11B a quarter earlier.

Buyers outnumbered sellers: 43 funds opened new CNTA positions and 20 closed out — a net gain of 23 holders — while 48 added to existing stakes and 44 trimmed.

The largest buyer was Avoro Capital Advisors, adding an estimated $94.9M. The largest seller was General Atlantic, cutting an estimated $90.3M.

  • 146 institutional investors held Centessa Pharmaceuticals (CNTA) as of Q4 2025, up from 125 in Q3 2025.
  • Funds reported $3.6B of Centessa Pharmaceuticals stock for Q4 2025, up 16% quarter-over-quarter.
  • 43 funds opened new Centessa Pharmaceuticals positions in Q4 2025 and 20 closed out, a net change of +23 holders.
  • The largest Centessa Pharmaceuticals buyer in Q4 2025 was Avoro Capital Advisors, an estimated $94.9M added.
  • The largest Centessa Pharmaceuticals seller in Q4 2025 was General Atlantic, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2025.