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Compass Therapeutics
CMPX

201 hedge funds and large institutions have $919M invested in Compass Therapeutics in 2026 Q1 according to their latest regulatory filings, with 50 funds opening new positions, 75 increasing their positions, 48 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,626% more call options, than puts

Call options by funds: $19.2M | Put options by funds: $1.11M

163% more first-time investments, than exits

New positions opened: 50 | Existing positions closed: 19

56% more repeat investments, than reductions

Existing positions increased: 75 | Existing positions reduced: 48

16% more funds holding

Funds holding: 173 → 201 (+28)

3.91% more ownership

Funds ownership: 92.29% → 96.2% (+3.9%)

4% more capital invested

Capital invested by funds: $881M → $919M (+$37.6M)

38% less funds holding in top 10

Funds holding in top 10: 8 → 5 (-3)

Holders
201
Holders Change
+28
Holders Change %
+16.18%
% of All Funds
2.47%
Holding in Top 10
5
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-37.5%
% of All Funds
0.06%
New
50
Increased
75
Reduced
48
Closed
19
Calls
$19.2M
Puts
$1.11M
Net Calls
+$18.1M
Net Calls Change
+$18.1M

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$23.4M
2
UBS Group
UBS Group
Switzerland
+$12.8M
3
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
+$12.2M
4
LGM
Logos Global Management
California
+$11.5M
5
State Street
State Street
Massachusetts
+$10.4M

Top Sellers

1
Blackstone Inc
Blackstone Inc
New York
-$24.6M
2
Millennium Management
Millennium Management
New York
-$13.1M
3
TECP
Trails Edge Capital Partners
Georgia
-$7.6M
4
SI
Sofinnova Investments
California
-$7.56M
5
Marshall Wace
Marshall Wace
United Kingdom
-$6.79M
Name Holding Trade Value Shares
Change 		Change in
Stake
PAI
26
Palo Alto Investors
California
$8.01M -$5.88M -1,017,915 -40%
BC
27
Birchview Capital
Vermont
$7.75M -$733K -127,071 -8%
GPP
28
Great Point Partners
Connecticut
$7.14M +$7.79M +1,350,000 New
Fisher Asset Management
29
Fisher Asset Management
Washington
$7.13M +$7.78M +1,348,259 New
Balyasny Asset Management
30
Balyasny Asset Management
Illinois
$5.92M -$2.74M -474,185 -30%
VPM
31
Vanguard Portfolio Management
Pennsylvania
$5.73M +$6.25M +1,082,651 New
SSA
32
Schonfeld Strategic Advisors
New York
$5.69M +$3.6M +623,562 +138%
Northern Trust
33
Northern Trust
Illinois
$5.55M +$436K +75,623 +8%
VFT
34
Vanguard Fiduciary Trust
Pennsylvania
$5.28M +$5.76M +998,140 New
Bank of America
35
Bank of America
North Carolina
$4.58M +$3.46M +599,179 +225%
SCM
36
Silverarc Capital Management
Massachusetts
$4.54M -$1.11M -192,294 -18%
ACP
37
Acuta Capital Partners
California
$4.49M -$1.41M -244,224 -22%
NCM
38
NEXTBio Capital Management
California
$4.49M -$1.53M -265,801 -24%
Millennium Management
39
Millennium Management
New York
$4.48M -$13.1M -2,263,066 -73%
YIH
40
Y-Intercept (HK)
Hong Kong
$4.38M +$2.12M +366,713 +79%
JP Morgan Chase
41
JP Morgan Chase
New York
$4.32M -$129K -22,312 -3%
Barclays
42
Barclays
United Kingdom
$4.18M +$1.13M +195,265 +33%
Citadel Advisors
43
Citadel Advisors
Florida
$3.82M +$3.55M +615,728 +583%
BGM
44
Burkehill Global Management
New York
$3.7M – – –
Citigroup
45
Citigroup
New York
$3.16M +$1.94M +336,362 +128%
HP
46
HealthInvest Partners
Sweden
$3.05M -$3.13M -542,501 -93%
SFCM
47
Seven Fleet Capital Management
California
$2.73M -$299K -51,775 -9%
ACH
48
ArrowMark Colorado Holdings
Colorado
$2.72M +$2.97M +514,793 New
KCA
49
KVP Capital Advisors
California
$2.65M +$2.89M +500,000 New
Connor, Clark & Lunn Investment Management (CC&L)
50
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.63M +$1.77M +306,094 +160%
1
2
3 4 5

CMPX Hedge Fund Activity: Q1 2026 in Review

201 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Compass Therapeutics (CMPX) for Q1 2026, worth a combined $919M — up 4.3% from $881M a quarter earlier.

Buyers outnumbered sellers: 50 funds opened new CMPX positions and 19 closed out — a net gain of 31 holders — while 75 added to existing stakes and 48 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $23.4M. The largest seller was Blackstone Inc, cutting an estimated $24.6M.

  • 201 institutional investors held Compass Therapeutics (CMPX) as of Q1 2026, up from 173 in Q4 2025.
  • Funds reported $919M of Compass Therapeutics stock for Q1 2026, up 4.3% quarter-over-quarter.
  • 50 funds opened new Compass Therapeutics positions in Q1 2026 and 19 closed out, a net change of +31 holders.
  • The largest Compass Therapeutics buyer in Q1 2026 was Adage Capital Partners, an estimated $23.4M added.
  • The largest Compass Therapeutics seller in Q1 2026 was Blackstone Inc, an estimated $24.6M sold.

Based on aggregated 13F filings for Q1 2026.