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Cabaletta Bio

86 hedge funds and large institutions have $111M invested in Cabaletta Bio in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 23 increasing their positions, 28 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,087% more call options, than puts

Call options by funds: $1.8M | Put options by funds: $152K

120% more capital invested

Capital invested by funds: $50.3M → $111M (+$60.3M)

69.13% more ownership

Funds ownership: 74.27%143.4% (+69%)

7% less funds holding

Funds holding: 9286 (-6)

18% less repeat investments, than reductions

Existing positions increased: 23 | Existing positions reduced: 28

19% less first-time investments, than exits

New positions opened: 26 | Existing positions closed: 32

Holders
86
Holders Change
-6
Holders Change %
-6.52%
% of All Funds
1.13%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
26
Increased
23
Reduced
28
Closed
32
Calls
$1.8M
Puts
$152K
Net Calls
+$1.65M
Net Calls Change
+$1.5M
Name Holding Trade Value Shares
Change
Change in
Stake
TRCT
51
Tower Research Capital (TRC)
New York
$77.6K +$69.6K +44,621 +696%
Charles Schwab
52
Charles Schwab
California
$76.9K -$170K -109,245 -68%
BNP Paribas Financial Markets
53
BNP Paribas Financial Markets
France
$74.6K -$19.2K -12,339 -20%
Bank of New York Mellon
54
Bank of New York Mellon
New York
$72.7K -$167K -107,364 -69%
BCM
55
Bridgeway Capital Management
Texas
$69.4K
MA
56
MYDA Advisors
New York
$60.8K +$62.4K +40,000 New
Manulife (Manufacturers Life Insurance)
57
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$60.5K -$26.9K -17,266 -30%
PAS
58
Point72 Asia (Singapore)
Singapore
$52.8K +$54.2K +34,767 New
AQR Capital Management
59
AQR Capital Management
Connecticut
$48.8K -$65.2K -41,827 -57%
VPIM
60
Vanguard Personalized Indexing Management
California
$37.9K +$8.69K +5,569 +29%
SG Americas Securities
61
SG Americas Securities
New York
$37K -$19.1K -12,228 -34%
CFM
62
Catalyst Funds Management
Australia
$31.9K +$32.8K +21,000 New
TSS
63
Two Sigma Securities
New York
$25.1K +$25.7K +16,491 New
RC
64
Rangeley Capital
Connecticut
$24.3K +$25K +16,000 New
Fidelity Investments
65
Fidelity Investments
Massachusetts
$23.5K +$17.6K +11,295 +271%
Acadian Asset Management
66
Acadian Asset Management
Massachusetts
$23K -$1.04M -667,529 -98%
Hudson Bay Capital Management
67
Hudson Bay Capital Management
Connecticut
$19.9K +$20.4K +13,070 New
DS
68
DRW Securities
Illinois
$19.5K +$20K +12,840 New
CFS
69
CRA Financial Services
New Jersey
$16.7K
Barclays
70
Barclays
United Kingdom
$14.8K -$72.8K -46,701 -83%
Wells Fargo
71
Wells Fargo
California
$10.2K -$39.4K -25,293 -79%
SS
72
SBI Securities
Japan
$9.9K +$5.61K +3,600 +123%
SSG
73
Summit Securities Group
New York
$7.33K +$7.52K +4,824 New
PD
74
Point72 (DIFC)
United Arab Emirates
$3.7K +$3.79K +2,432 New
TC
75
Truvestments Capital
Florida
$3K

CABA Hedge Fund Activity: Q2 2025 in Review

86 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Cabaletta Bio (CABA) for Q2 2025, worth a combined $111M — up 120% from $50.3M a quarter earlier.

Sellers outnumbered buyers: 32 funds closed out of CABA and 26 opened new positions — a net loss of 6 holders — while 28 trimmed existing stakes and 23 added.

The largest buyer was Bain Capital Life Sciences Investors, adding an estimated $10.8M. The largest seller was BlackRock, cutting an estimated $3.87M.

  • 86 institutional investors held Cabaletta Bio (CABA) as of Q2 2025, down from 92 in Q1 2025.
  • Funds reported $111M of Cabaletta Bio stock for Q2 2025, up 120% quarter-over-quarter.
  • 26 funds opened new Cabaletta Bio positions in Q2 2025 and 32 closed out, a net change of -6 holders.
  • The largest Cabaletta Bio buyer in Q2 2025 was Bain Capital Life Sciences Investors, an estimated $10.8M added.
  • The largest Cabaletta Bio seller in Q2 2025 was BlackRock, an estimated $3.87M sold.

Based on aggregated 13F filings for Q2 2025.