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Cabaletta Bio

75 hedge funds and large institutions have $162M invested in Cabaletta Bio in 2025 Q3 according to their latest regulatory filings, with 10 funds opening new positions, 24 increasing their positions, 31 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

5,676% more call options, than puts

Call options by funds: $5.26M | Put options by funds: $91K

46% more capital invested

Capital invested by funds: $111M → $162M (+$51.3M)

13% less funds holding

Funds holding: 8675 (-11)

23% less repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 31

52% less first-time investments, than exits

New positions opened: 10 | Existing positions closed: 21

67.73% less ownership

Funds ownership: 143.4%75.67% (-68%)

Holders
75
Holders Change
-11
Holders Change %
-12.79%
% of All Funds
0.98%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
10
Increased
24
Reduced
31
Closed
21
Calls
$5.26M
Puts
$91K
Net Calls
+$5.17M
Net Calls Change
+$3.51M
Name Holding Trade Value Shares
Change
Change in
Stake
State Street
26
State Street
Massachusetts
$882K +$273K +158,833 +73%
Susquehanna International Group
27
Susquehanna International Group
Pennsylvania
$871K +$426K +248,483 +201%
RBI
28
Raiffeisen Bank International
Austria
$833K +$85.8K +50,000 +17%
Two Sigma Advisers
29
Two Sigma Advisers
New York
$775K -$142K -82,600 -20%
XT
30
XTX Topco
Cayman Islands
$665K +$321K +187,039 +192%
Goldman Sachs
31
Goldman Sachs
New York
$638K -$138K -80,711 -23%
Bank of America
32
Bank of America
North Carolina
$627K -$395K -230,185 -46%
Northern Trust
33
Northern Trust
Illinois
$531K +$161K +93,967 +71%
Acadian Asset Management
34
Acadian Asset Management
Massachusetts
$433K +$294K +171,380 +1,132%
Invesco
35
Invesco
Georgia
$287K +$65.1K +37,969 +45%
Federated Hermes
36
Federated Hermes
Pennsylvania
$262K -$399K -232,512 -67%
Jane Street
37
Jane Street
New York
$245K -$229K -133,663 -56%
BCM
38
Bridgeway Capital Management
Texas
$224K +$85.8K +50,000 +109%
Royal Bank of Canada
39
Royal Bank of Canada
Ontario, Canada
$214K +$157K +91,660 +145,492%
Qube Research & Technologies (QRT)
40
Qube Research & Technologies (QRT)
United Kingdom
$209K +$153K +89,157 New
TD Asset Management
41
TD Asset Management
Ontario, Canada
$207K
FAM
42
Fred Alger Management
New York
$140K
Charles Schwab
43
Charles Schwab
California
$119K +$348 +203 +0.4%
Bank of New York Mellon
44
Bank of New York Mellon
New York
$112K
JFG
45
Jefferies Financial Group
New York
$111K -$3.35M -1,949,708 -98%
QC
46
Quadrature Capital
United Kingdom
$100K +$73.6K +42,912 New
CSS
47
Cubist Systematic Strategies
Connecticut
$88.3K -$339K -197,526 -84%
SPS
48
Susquehanna Portfolio Strategies
Pennsylvania
$79.4K +$58.2K +33,937 New
VPIM
49
Vanguard Personalized Indexing Management
California
$51.8K -$4.8K -2,797 -11%
SG Americas Securities
50
SG Americas Securities
New York
$50K -$4.78K -2,784 -12%

CABA Hedge Fund Activity: Q3 2025 in Review

75 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Cabaletta Bio (CABA) for Q3 2025, worth a combined $162M — up 46% from $111M a quarter earlier.

Sellers outnumbered buyers: 21 funds closed out of CABA and 10 opened new positions — a net loss of 11 holders — while 31 trimmed existing stakes and 24 added.

The largest buyer was Jennison Associates, adding an estimated $4.25M. The largest seller was Alyeska Investment Group, cutting an estimated $6.01M.

  • 75 institutional investors held Cabaletta Bio (CABA) as of Q3 2025, down from 86 in Q2 2025.
  • Funds reported $162M of Cabaletta Bio stock for Q3 2025, up 46% quarter-over-quarter.
  • 10 funds opened new Cabaletta Bio positions in Q3 2025 and 21 closed out, a net change of -11 holders.
  • The largest Cabaletta Bio buyer in Q3 2025 was Jennison Associates, an estimated $4.25M added.
  • The largest Cabaletta Bio seller in Q3 2025 was Alyeska Investment Group, an estimated $6.01M sold.

Based on aggregated 13F filings for Q3 2025.