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BlackRock Health Sciences Trust
BME

77 hedge funds and large institutions have $114M invested in BlackRock Health Sciences Trust in 2025 Q4 according to their latest regulatory filings, with 12 funds opening new positions, 24 increasing their positions, 23 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

20% more first-time investments, than exits

New positions opened: 12 | Existing positions closed: 10

7% more capital invested

Capital invested by funds: $106M → $114M (+$7.93M)

1% more funds holding

Funds holding: 76 → 77 (+1)

4% more repeat investments, than reductions

Existing positions increased: 24 | Existing positions reduced: 23

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

0.59% less ownership

Funds ownership: 21.59% → 21% (-0.59%)

Holders
77
Holders Change
+1
Holders Change %
+1.32%
% of All Funds
0.94%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
12
Increased
24
Reduced
23
Closed
10
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
1CP
1607 Capital Partners
Virginia
+$3M
2
KIM
Karpus Investment Management
New York
+$2.9M
3
Bank of America
Bank of America
North Carolina
+$2.88M
4
Royal Bank of Canada
Royal Bank of Canada
Ontario, Canada
+$728K
5
Morgan Stanley
Morgan Stanley
New York
+$666K

Top Sellers

Rank Fund Capital Flow
1
Wells Fargo
Wells Fargo
California
-$7.33M
2
WAM
Wolverine Asset Management
Illinois
-$2.28M
3
CPRC
Consolidated Portfolio Review Corp
New York
-$2.03M
4
Invesco
Invesco
Georgia
-$999K
5
NRW
Nova R Wealth
Kansas
-$910K
Name Holding Trade Value Shares
Change 		Change in
Stake
FFA
26
Founders Financial Alliance
North Carolina
$711K -$78.2K -1,981 -10%
Rockefeller Capital Management
27
Rockefeller Capital Management
New York
$653K -$7.9K -200 -1%
HC
28
Hara Capital
Washington
$631K – – –
NA
29
NewEdge Advisors
Louisiana
$557K -$2.25K -57 -0.4%
HSA
30
HBK Sorce Advisory
Pennsylvania
$554K +$18.8K +476 +4%
Cetera Investment Advisers
31
Cetera Investment Advisers
Illinois
$544K +$58.4K +1,478 +13%
SAM
32
Smith Asset Management
Florida
$530K +$90.9K +2,301 +22%
NS
33
NBC Securities
Alabama
$486K -$3.24K -82 -0.7%
DE
34
Diversified Enterprises
Delaware
$450K +$3.44K +87 +0.8%
Millennium Management
35
Millennium Management
New York
$430K +$412K +10,443 New
Stifel Financial
36
Stifel Financial
Missouri
$394K -$40.5K -1,025 -10%
National Bank of Canada
37
National Bank of Canada
Quebec, Canada
$299K +$287K +7,275 New
SWP
38
Stratos Wealth Partners
Ohio
$298K -$17.1K -434 -6%
Envestnet Asset Management
39
Envestnet Asset Management
Illinois
$295K +$61K +1,545 +27%
ACM
40
Alessandra Capital Management
California
$291K +$280K +7,085 New
HIP
41
HUB Investment Partners
Texas
$288K +$276K +7,000 New
Jane Street
42
Jane Street
New York
$281K +$5.05K +128 +2%
Truist Financial
43
Truist Financial
North Carolina
$280K +$51.6K +1,306 +24%
OC
44
Oppenheimer & Co
New York
$279K +$2.88K +73 +1%
PNC Financial Services Group
45
PNC Financial Services Group
Pennsylvania
$265K +$132K +3,354 +108%
PFO
46
PMG Family Office
Texas
$265K -$89.5K -2,266 -26%
WW
47
Waterfront Wealth
Kansas
$223K -$11.8K -300 -5%
SIC
48
Sage Investment Counsel
Tennessee
$222K – – –
LSIA
49
LaSalle St. Investment Advisors
Illinois
$209K +$201K +5,087 New
GWM
50
Geneos Wealth Management
Colorado
$201K – – –
1
2
3 4

BME Hedge Fund Activity: Q4 2025 in Review

77 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in BlackRock Health Sciences Trust (BME) for Q4 2025, worth a combined $114M — up 7.5% from $106M a quarter earlier.

Buyers outnumbered sellers: 12 funds opened new BME positions and 10 closed out — a net gain of 2 holders — while 24 added to existing stakes and 23 trimmed.

The largest buyer was 1607 Capital Partners, adding an estimated $3M. The largest seller was Wells Fargo, cutting an estimated $7.33M.

  • 77 institutional investors held BlackRock Health Sciences Trust (BME) as of Q4 2025, up from 76 in Q3 2025.
  • Funds reported $114M of BlackRock Health Sciences Trust stock for Q4 2025, up 7.5% quarter-over-quarter.
  • 12 funds opened new BlackRock Health Sciences Trust positions in Q4 2025 and 10 closed out, a net change of +2 holders.
  • The largest BlackRock Health Sciences Trust buyer in Q4 2025 was 1607 Capital Partners, an estimated $3M added.
  • The largest BlackRock Health Sciences Trust seller in Q4 2025 was Wells Fargo, an estimated $7.33M sold.

Based on aggregated 13F filings for Q4 2025.