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905 hedge funds and large institutions have $18.5B invested in Biogen in 2025 Q3 according to their latest regulatory filings, with 122 funds opening new positions, 322 increasing their positions, 269 reducing their positions, and 74 closing their positions.

New
Increased
Maintained
Reduced
Closed

81% more call options, than puts

Call options by funds: $573M | Put options by funds: $316M

65% more first-time investments, than exits

New positions opened: 122 | Existing positions closed: 74

20% more repeat investments, than reductions

Existing positions increased: 322 | Existing positions reduced: 269

13% more capital invested

Capital invested by funds: $16.4B → $18.5B (+$2.11B)

5% more funds holding

Funds holding: 866905 (+39)

0.76% more ownership

Funds ownership: 88.8%89.57% (+0.76%)

40% less funds holding in top 10

Funds holding in top 10: 53 (-2)

Holders
905
Holders Change
+39
Holders Change %
+4.5%
% of All Funds
11.88%
Holding in Top 10
3
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-40%
% of All Funds
0.04%
New
122
Increased
322
Reduced
269
Closed
74
Calls
$573M
Puts
$316M
Net Calls
+$257M
Net Calls Change
+$209M
Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Associates
26
T. Rowe Price Associates
Maryland
$135M +$17.8M +131,530 +16%
Renaissance Technologies
27
Renaissance Technologies
New York
$135M -$10.9M -80,700 -8%
Man Group
28
Man Group
United Kingdom
$129M +$16.9M +124,743 +16%
Marshall Wace
29
Marshall Wace
United Kingdom
$124M +$97.6M +721,706 +435%
Bank of New York Mellon
30
Bank of New York Mellon
New York
$124M -$2.62M -19,353 -2%
Dimensional Fund Advisors
31
Dimensional Fund Advisors
Texas
$122M -$7.49M -55,402 -6%
Alyeska Investment Group
32
Alyeska Investment Group
Illinois
$118M +$45.5M +336,504 +66%
First Trust Advisors
33
First Trust Advisors
Illinois
$118M -$4.5M -33,266 -4%
Pictet Asset Management
34
Pictet Asset Management
Switzerland
$108M +$73.2M +541,513 +236%
A
35
AustralianSuper
Australia
$105M +$1.62M +11,970 +2%
Massachusetts Financial Services
36
Massachusetts Financial Services
Massachusetts
$102M +$1.58M +11,685 +2%
RIM
37
Rakuten Investment Management
Japan
$99.1M +$26.8M +198,572 New
EPFB
38
Employees Provident Fund Board
Malaysia
$98.6M
Amundi
39
Amundi
France
$95.3M +$5.21M +38,512 +7%
Robeco Institutional Asset Management
40
Robeco Institutional Asset Management
Netherlands
$94M +$30M +222,297 +50%
UBS Group
41
UBS Group
Switzerland
$89.5M +$26.1M +193,281 +43%
Caisse de Depot et Placement du Quebec (CDPQ)
42
Caisse de Depot et Placement du Quebec (CDPQ)
Quebec, Canada
$79.7M +$67.5M +499,676 +718%
CCM
43
Causeway Capital Management
California
$79.5M +$10M +74,163 +15%
Royal Bank of Canada
44
Royal Bank of Canada
Ontario, Canada
$69.8M +$266K +1,968 +0.4%
D.E. Shaw & Co
45
D.E. Shaw & Co
New York
$66.9M -$120M -888,283 -65%
HSBC Holdings
46
HSBC Holdings
United Kingdom
$62.6M +$574K +4,249 +1%
Susquehanna International Group
47
Susquehanna International Group
Pennsylvania
$61.8M -$20.7M -153,017 -26%
Prudential Financial
48
Prudential Financial
New Jersey
$61.5M +$6.93M +51,280 +13%
Swiss National Bank
49
Swiss National Bank
Switzerland
$59.2M -$2.8M -20,700 -5%
Sumitomo Mitsui Trust Group
50
Sumitomo Mitsui Trust Group
Japan
$58.2M +$105K +779 +0.2%

BIIB Hedge Fund Activity: Q3 2025 in Review

905 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Biogen (BIIB) for Q3 2025, worth a combined $18.5B — up 13% from $16.4B a quarter earlier.

Buyers outnumbered sellers: 122 funds opened new BIIB positions and 74 closed out — a net gain of 48 holders — while 322 added to existing stakes and 269 trimmed.

The largest buyer was BlackRock, adding an estimated $163M. The largest seller was D.E. Shaw & Co, cutting an estimated $120M.

  • 905 institutional investors held Biogen (BIIB) as of Q3 2025, up from 866 in Q2 2025.
  • Funds reported $18.5B of Biogen stock for Q3 2025, up 13% quarter-over-quarter.
  • 122 funds opened new Biogen positions in Q3 2025 and 74 closed out, a net change of +48 holders.
  • The largest Biogen buyer in Q3 2025 was BlackRock, an estimated $163M added.
  • The largest Biogen seller in Q3 2025 was D.E. Shaw & Co, an estimated $120M sold.

Based on aggregated 13F filings for Q3 2025.