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ATYR

aTyr Pharma
ATYR

110 hedge funds and large institutions have $336M invested in aTyr Pharma in 2025 Q2 according to their latest regulatory filings, with 52 funds opening new positions, 25 increasing their positions, 24 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

80% more capital invested

Capital invested by funds: $187M → $336M (+$150M)

79% more first-time investments, than exits

New positions opened: 52 | Existing positions closed: 29

54% more call options, than puts

Call options by funds: $5.88M | Put options by funds: $3.81M

26% more funds holding

Funds holding: 87 → 110 (+23)

5.06% more ownership

Funds ownership: 69.5% → 74.56% (+5.1%)

4% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 24

Holders
110
Holders Change
+23
Holders Change %
+26.44%
% of All Funds
1.45%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
% of All Funds
0.03%
New
52
Increased
25
Reduced
24
Closed
29
Calls
$5.88M
Puts
$3.81M
Net Calls
+$2.07M
Net Calls Change
+$3.61M

Top Buyers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
+$16.5M
2
Geode Capital Management
Geode Capital Management
Massachusetts
+$4.6M
3
State Street
State Street
Massachusetts
+$3.43M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$2.55M
5
Invesco
Invesco
Georgia
+$2.35M

Top Sellers

Rank Fund Capital Flow
1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$7.3M
2
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$5.82M
3
ABG
Ally Bridge Group
New York
-$1.93M
4
Goldman Sachs
Goldman Sachs
New York
-$1.36M
5
Marshall Wace
Marshall Wace
United Kingdom
-$1.29M
Name Holding Trade Value Shares
Change 		Change in
Stake
TC
126
TwinBeech Capital
New York
– -$64.7K -21,434 Closed
CM
127
Capula Management
Cayman Islands
– -$63.8K -21,126 Closed
XT
128
XTX Topco
Cayman Islands
– -$59.1K -19,556 Closed
EGM
129
Engineers Gate Manager
New York
– -$58.3K -19,288 Closed
Capstone Investment Advisors
130
Capstone Investment Advisors
New York
– -$55.6K -18,420 Closed
BFM
131
Boothbay Fund Management
New York
– -$44K -14,568 Closed
Hudson Bay Capital Management
132
Hudson Bay Capital Management
Connecticut
– -$40.2K -13,320 Closed
YIH
133
Y-Intercept (HK)
Hong Kong
– -$38K -12,583 Closed
TSS
134
Two Sigma Securities
New York
– -$36K -11,935 Closed
AWM
135
Alterna Wealth Management
Texas
– -$30.2K -10,000 Closed
PAS
136
Point72 Asia (Singapore)
Singapore
– -$3.79K -1,255 Closed
PP
137
PFS Partners
New Jersey
– -$1.03K -340 Closed
CA
138
Continuum Advisory
Idaho
– -$634 -210 Closed
SIS
139
Strategic Investment Solutions
Illinois
– -$24 -8 Closed
2 3 4 5
6

ATYR Hedge Fund Activity: Q2 2025 in Review

110 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in aTyr Pharma (ATYR) for Q2 2025, worth a combined $336M — up 80% from $187M a quarter earlier.

Buyers outnumbered sellers: 52 funds opened new ATYR positions and 29 closed out — a net gain of 23 holders — while 25 added to existing stakes and 24 trimmed.

The largest buyer was BlackRock, adding an estimated $16.5M. The largest seller was Point72 Asset Management, cutting an estimated $7.3M.

  • 110 institutional investors held aTyr Pharma (ATYR) as of Q2 2025, up from 87 in Q1 2025.
  • Funds reported $336M of aTyr Pharma stock for Q2 2025, up 80% quarter-over-quarter.
  • 52 funds opened new aTyr Pharma positions in Q2 2025 and 29 closed out, a net change of +23 holders.
  • The largest aTyr Pharma buyer in Q2 2025 was BlackRock, an estimated $16.5M added.
  • The largest aTyr Pharma seller in Q2 2025 was Point72 Asset Management, an estimated $7.3M sold.

Based on aggregated 13F filings for Q2 2025.