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ATYR

aTyr Pharma
ATYR

110 hedge funds and large institutions have $336M invested in aTyr Pharma in 2025 Q2 according to their latest regulatory filings, with 52 funds opening new positions, 25 increasing their positions, 24 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

80% more capital invested

Capital invested by funds: $187M → $336M (+$150M)

79% more first-time investments, than exits

New positions opened: 52 | Existing positions closed: 29

54% more call options, than puts

Call options by funds: $5.88M | Put options by funds: $3.81M

26% more funds holding

Funds holding: 87 → 110 (+23)

5.06% more ownership

Funds ownership: 69.5% → 74.56% (+5.1%)

4% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 24

Holders
110
Holders Change
+23
Holders Change %
+26.44%
% of All Funds
1.45%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
% of All Funds
0.03%
New
52
Increased
25
Reduced
24
Closed
29
Calls
$5.88M
Puts
$3.81M
Net Calls
+$2.07M
Net Calls Change
+$3.61M

Top Buyers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
+$16.5M
2
Geode Capital Management
Geode Capital Management
Massachusetts
+$4.6M
3
State Street
State Street
Massachusetts
+$3.43M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$2.55M
5
Invesco
Invesco
Georgia
+$2.35M

Top Sellers

Rank Fund Capital Flow
1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$7.3M
2
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$5.82M
3
ABG
Ally Bridge Group
New York
-$1.93M
4
Goldman Sachs
Goldman Sachs
New York
-$1.36M
5
Marshall Wace
Marshall Wace
United Kingdom
-$1.29M
Name Holding Trade Value Shares
Change 		Change in
Stake
PG
101
Proffitt & Goodson
Tennessee
$4.46K +$3.46K +880 New
S
102
Sachetta
Massachusetts
$4.21K – – –
HNB
103
Huntington National Bank
Ohio
$3.55K +$2.75K +700 New
NS
104
NBC Securities
Alabama
$3K – – –
NFSG
105
Newbridge Financial Services Group
Florida
$2.54K +$1.97K +500 New
SCM
106
Sterling Capital Management
North Carolina
$1.8K +$1.4K +355 New
GRP
107
Global Retirement Partners
California
$1.52K +$1.18K +300 New
GC
108
Garde Capital
Washington
$1.01K +$787 +200 New
RIL
109
Rothschild Investment LLC
Illinois
$456 +$354 +90 New
CSC
110
Caldwell Sutter Capital
California
$264 – – –
Qube Research & Technologies (QRT)
111
Qube Research & Technologies (QRT)
United Kingdom
– -$1.25M -414,592 Closed
Squarepoint
112
Squarepoint
New York
– -$710K -235,242 Closed
Balyasny Asset Management
113
Balyasny Asset Management
Illinois
– -$686K -227,142 Closed
HF
114
HRT Financial
New York
– -$550K -182,135 Closed
JG
115
Jain Global
New York
– -$266K -88,143 Closed
QC
116
Quantessence Capital
New York
– -$186K -61,621 Closed
JFG
117
Jefferies Financial Group
New York
– -$168K -55,600 Closed
BHCM
118
Brevan Howard Capital Management
Jersey
– -$161K -53,209 Closed
LP
119
LMR Partners
United Kingdom
– -$157K -52,087 Closed
ECM
120
ExodusPoint Capital Management
New York
– -$146K -48,227 Closed
CGIM
121
Cannon Global Investment Management
Florida
– -$143K -47,500 Closed
Verition Fund Management
122
Verition Fund Management
Connecticut
– -$137K -45,451 Closed
Wolverine Trading
123
Wolverine Trading
Illinois
– -$142K -45,327 Closed
JGC
124
J. Goldman & Co
New York
– -$91K -30,131 Closed
American Century Companies
125
American Century Companies
Missouri
– -$68.6K -22,703 Closed
2 3 4
5
6

ATYR Hedge Fund Activity: Q2 2025 in Review

110 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in aTyr Pharma (ATYR) for Q2 2025, worth a combined $336M — up 80% from $187M a quarter earlier.

Buyers outnumbered sellers: 52 funds opened new ATYR positions and 29 closed out — a net gain of 23 holders — while 25 added to existing stakes and 24 trimmed.

The largest buyer was BlackRock, adding an estimated $16.5M. The largest seller was Point72 Asset Management, cutting an estimated $7.3M.

  • 110 institutional investors held aTyr Pharma (ATYR) as of Q2 2025, up from 87 in Q1 2025.
  • Funds reported $336M of aTyr Pharma stock for Q2 2025, up 80% quarter-over-quarter.
  • 52 funds opened new aTyr Pharma positions in Q2 2025 and 29 closed out, a net change of +23 holders.
  • The largest aTyr Pharma buyer in Q2 2025 was BlackRock, an estimated $16.5M added.
  • The largest aTyr Pharma seller in Q2 2025 was Point72 Asset Management, an estimated $7.3M sold.

Based on aggregated 13F filings for Q2 2025.