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ATYR

aTyr Pharma
ATYR

110 hedge funds and large institutions have $336M invested in aTyr Pharma in 2025 Q2 according to their latest regulatory filings, with 52 funds opening new positions, 25 increasing their positions, 24 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

80% more capital invested

Capital invested by funds: $187M → $336M (+$150M)

79% more first-time investments, than exits

New positions opened: 52 | Existing positions closed: 29

54% more call options, than puts

Call options by funds: $5.88M | Put options by funds: $3.81M

26% more funds holding

Funds holding: 87 → 110 (+23)

5.06% more ownership

Funds ownership: 69.5% → 74.56% (+5.1%)

4% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 24

Holders
110
Holders Change
+23
Holders Change %
+26.44%
% of All Funds
1.45%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
% of All Funds
0.03%
New
52
Increased
25
Reduced
24
Closed
29
Calls
$5.88M
Puts
$3.81M
Net Calls
+$2.07M
Net Calls Change
+$3.61M

Top Buyers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
+$16.5M
2
Geode Capital Management
Geode Capital Management
Massachusetts
+$4.6M
3
State Street
State Street
Massachusetts
+$3.43M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$2.55M
5
Invesco
Invesco
Georgia
+$2.35M

Top Sellers

Rank Fund Capital Flow
1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$7.3M
2
Susquehanna International Group
Susquehanna International Group
Pennsylvania
-$5.82M
3
ABG
Ally Bridge Group
New York
-$1.93M
4
Goldman Sachs
Goldman Sachs
New York
-$1.36M
5
Marshall Wace
Marshall Wace
United Kingdom
-$1.29M
Name Holding Trade Value Shares
Change 		Change in
Stake
Morgan Stanley
26
Morgan Stanley
New York
$1.32M -$10.7K -2,713 -1%
Charles Schwab
27
Charles Schwab
California
$1.31M +$860K +218,640 +548%
Susquehanna International Group
28
Susquehanna International Group
Pennsylvania
$1.29M -$5.82M -1,479,063 -85%
Ensign Peak Advisors
29
Ensign Peak Advisors
Utah
$1.19M +$927K +235,675 New
Wellington Management Group
30
Wellington Management Group
Massachusetts
$1.09M +$182K +46,186 +27%
Dimensional Fund Advisors
31
Dimensional Fund Advisors
Texas
$1.09M -$53.3K -13,548 -6%
TFS
32
Thoroughbred Financial Services
Tennessee
$1.07M +$829K +210,775 New
N
33
Nuveen
North Carolina
$984K +$764K +194,112 New
Bank of New York Mellon
34
Bank of New York Mellon
New York
$942K +$731K +185,894 New
DIG
35
Dauntless Investment Group
New Hampshire
$803K -$48.3K -12,287 -7%
PHP
36
Parkman Healthcare Partners
Connecticut
$761K +$590K +150,000 New
MSFS
37
Main Street Financial Solutions
Pennsylvania
$728K +$36.8K +9,350 +7%
RhumbLine Advisers
38
RhumbLine Advisers
Massachusetts
$629K +$488K +124,158 New
Citadel Advisors
39
Citadel Advisors
Florida
$604K -$558K -141,890 -54%
Royal Bank of Canada
40
Royal Bank of Canada
Ontario, Canada
$487K +$281K +71,463 +289%
FAM
41
Fred Alger Management
New York
$469K +$364K +92,493 New
SSA
42
Schonfeld Strategic Advisors
New York
$392K -$100K -25,442 -25%
Group One Trading
43
Group One Trading
Illinois
$359K -$74.4K -18,904 -21%
AllianceBernstein
44
AllianceBernstein
Tennessee
$327K +$49.4K +12,563 +24%
Deutsche Bank
45
Deutsche Bank
Germany
$306K +$237K +60,296 New
AAS
46
Avantax Advisory Services
Texas
$292K +$227K +57,669 New
QC
47
Quadrature Capital
United Kingdom
$283K +$220K +56,022 New
DMKJ
48
David M. Knott Jr
$255K -$681K -173,040 -77%
Mirae Asset Global ETFs Holdings
49
Mirae Asset Global ETFs Holdings
Hong Kong
$242K +$187K +47,643 New
IIM
50
INTECH Investment Management
Florida
$226K +$176K +44,668 New
1
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ATYR Hedge Fund Activity: Q2 2025 in Review

110 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in aTyr Pharma (ATYR) for Q2 2025, worth a combined $336M — up 80% from $187M a quarter earlier.

Buyers outnumbered sellers: 52 funds opened new ATYR positions and 29 closed out — a net gain of 23 holders — while 25 added to existing stakes and 24 trimmed.

The largest buyer was BlackRock, adding an estimated $16.5M. The largest seller was Point72 Asset Management, cutting an estimated $7.3M.

  • 110 institutional investors held aTyr Pharma (ATYR) as of Q2 2025, up from 87 in Q1 2025.
  • Funds reported $336M of aTyr Pharma stock for Q2 2025, up 80% quarter-over-quarter.
  • 52 funds opened new aTyr Pharma positions in Q2 2025 and 29 closed out, a net change of +23 holders.
  • The largest aTyr Pharma buyer in Q2 2025 was BlackRock, an estimated $16.5M added.
  • The largest aTyr Pharma seller in Q2 2025 was Point72 Asset Management, an estimated $7.3M sold.

Based on aggregated 13F filings for Q2 2025.