|
26
|
Polar Capital
London,
United Kingdom
|
–
|
-$15.4M
|
-1,235,000
|
Closed
|
|
|
27
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
–
|
-$15.2M
|
-1,225,891
|
Closed
|
|
|
28
|
|
–
|
-$13.4M
|
-1,076,629
|
Closed
|
|
|
29
|
Bank of New York Mellon
New York
|
–
|
-$12.5M
|
-1,005,186
|
Closed
|
|
|
30
|
Opaleye Management
Boston,
Massachusetts
|
–
|
-$12.4M
|
-1,000,000
|
Closed
|
|
|
31
|
HBK Investments
Dallas,
Texas
|
–
|
-$11.8M
|
-947,249
|
Closed
|
|
|
32
|
|
–
|
-$11.7M
|
-940,000
|
Closed
|
|
|
33
|
Rhenman & Partners Asset Management
Stockholm,
Sweden
|
–
|
-$11.1M
|
-895,000
|
Closed
|
|
|
34
|
Tamarack Advisers
Carlsbad,
California
|
–
|
-$10.6M
|
-850,000
|
Closed
|
|
|
35
|
Charles Schwab
San Francisco,
California
|
–
|
-$9.68M
|
-778,437
|
Closed
|
|
|
36
|
|
–
|
-$9.68M
|
-777,786
|
Closed
|
|
|
37
|
Renaissance Technologies
New York
|
–
|
-$9.48M
|
-762,481
|
Closed
|
|
|
38
|
General American Investors
New York
|
–
|
-$8.88M
|
-714,100
|
Closed
|
|
|
39
|
International Biotechnology Trust
London,
United Kingdom
|
–
|
-$8.18M
|
-657,912
|
Closed
|
|
|
40
|
HighVista Strategies
Boston,
Massachusetts
|
–
|
-$7.94M
|
-638,086
|
Closed
|
|
|
41
|
Commerzbank Aktiengesellschaft
Frankfurt,
Germany
|
–
|
-$7.62M
|
-612,886
|
Closed
|
|
|
42
|
Voloridge Investment Management
Jupiter,
Florida
|
–
|
-$7.48M
|
-601,463
|
Closed
|
|
|
43
|
Two Sigma Advisers
New York
|
–
|
-$7.08M
|
-568,749
|
Closed
|
|
|
44
|
Elk Creek Partners
Denver,
Colorado
|
–
|
-$6.76M
|
-543,063
|
Closed
|
|
|
45
|
TIAA CREF Investment Management
New York
|
–
|
-$6.34M
|
-509,592
|
Closed
|
|
|
46
|
Granite Point Capital Management
Boston,
Massachusetts
|
–
|
-$5.8M
|
-466,015
|
Closed
|
|
|
47
|
|
–
|
-$5.21M
|
-418,650
|
Closed
|
|
|
48
|
Bellevue Group
Kuesnacht,
Switzerland
|
–
|
-$4.67M
|
-375,000
|
Closed
|
|
|
49
|
UBS Group
Zurich,
Switzerland
|
–
|
-$4.61M
|
-370,402
|
Closed
|
|
|
50
|
California State Teachers Retirement System (CalSTRS)
West Sacramento,
California
|
–
|
-$4.54M
|
-364,838
|
Closed
|
|
