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Ardelyx
ARDX

221 hedge funds and large institutions have $809M invested in Ardelyx in 2025 Q1 according to their latest regulatory filings, with 42 funds opening new positions, 90 increasing their positions, 55 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

64% more repeat investments, than reductions

Existing positions increased: 90 | Existing positions reduced: 55

31% more first-time investments, than exits

New positions opened: 42 | Existing positions closed: 32

6% more capital invested

Capital invested by funds: $765M → $809M (+$43.4M)

5.34% more ownership

Funds ownership: 63.73% → 69.07% (+5.3%)

4% more funds holding

Funds holding: 213 → 221 (+8)

14% less call options, than puts

Call options by funds: $11.5M | Put options by funds: $13.3M

33% less funds holding in top 10

Funds holding in top 10: 3 → 2 (-1)

Holders
221
Holders Change
+8
Holders Change %
+3.76%
% of All Funds
2.96%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
42
Increased
90
Reduced
55
Closed
32
Calls
$11.5M
Puts
$13.3M
Net Calls
-$1.83M
Net Calls Change
+$2.5M

Top Buyers

1
Marshall Wace
Marshall Wace
United Kingdom
+$44.4M
2
Millennium Management
Millennium Management
New York
+$18.8M
3
Renaissance Technologies
Renaissance Technologies
New York
+$7.26M
4
N
Nuveen
North Carolina
+$6.64M
5
Jane Street
Jane Street
New York
+$6.54M

Top Sellers

1
EAM
Eventide Asset Management
Massachusetts
-$28.4M
2
RCMNY
Rubric Capital Management (New York)
New York
-$8.65M
3
RG
Redmile Group
California
-$7.99M
4
State Street
State Street
Massachusetts
-$7.61M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
-$6.76M
Name Holding Trade Value Shares
Change 		Change in
Stake
CUAMC
126
China Universal Asset Management Company
China
$235K -$13K -2,412 -5%
Ameriprise
127
Ameriprise
Minnesota
$229K +$27.7K +5,160 +12%
Fidelity Investments
128
Fidelity Investments
Massachusetts
$219K +$22.8K +4,246 +11%
BHCM
129
Brevan Howard Capital Management
Jersey
$196K +$100K +18,655 +87%
PCA
130
Pallas Capital Advisors
Massachusetts
$182K +$199K +37,087 New
EFM
131
E Fund Management
China
$181K -$5.69K -1,059 -3%
Creative Planning
132
Creative Planning
Kansas
$174K +$104K +19,342 +121%
VRS
133
Virginia Retirement Systems
Virginia
$163K +$178K +33,200 New
Pictet Asset Management
134
Pictet Asset Management
Switzerland
$159K – – –
SB
135
SIG Brokerage
New York
$157K +$171K +31,891 New
EC
136
EntryPoint Capital
New York
$156K -$8.79K -1,637 -5%
VFA
137
Values First Advisors
Tennessee
$148K -$3.37K -628 -2%
Connor, Clark & Lunn Investment Management (CC&L)
138
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$144K +$157K +29,324 New
WMA
139
West Michigan Advisors
Michigan
$137K – – –
Victory Capital Management
140
Victory Capital Management
Texas
$137K -$2.07K -385 -1%
PWM
141
Palumbo Wealth Management
New York
$136K +$56.9K +10,597 +62%
SO
142
STRS Ohio
Ohio
$135K – – –
HSBC Holdings
143
HSBC Holdings
United Kingdom
$132K -$1.37M -254,579 -90%
Commonwealth Equity Services
144
Commonwealth Equity Services
Massachusetts
$131K -$14.8K -2,764 -9%
William Blair & Company
145
William Blair & Company
Illinois
$122K +$53.7K +10,000 +68%
Public Employees Retirement Association of Colorado
146
Public Employees Retirement Association of Colorado
Colorado
$120K – – –
GAM
147
Gotham Asset Management
New York
$118K +$129K +23,996 New
AIP
148
Ameritas Investment Partners
Nebraska
$117K – – –
Toronto Dominion Bank
149
Toronto Dominion Bank
Ontario, Canada
$117K +$128K +23,750 New
CWA
150
Crux Wealth Advisors
California
$114K -$220 -41 -0.2%
4 5
6
7 8

ARDX Hedge Fund Activity: Q1 2025 in Review

221 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Ardelyx (ARDX) for Q1 2025, worth a combined $809M — up 5.7% from $765M a quarter earlier.

Buyers outnumbered sellers: 42 funds opened new ARDX positions and 32 closed out — a net gain of 10 holders — while 90 added to existing stakes and 55 trimmed.

The largest buyer was Marshall Wace, adding an estimated $44.4M. The largest seller was Eventide Asset Management, exiting entirely with an estimated $28.4M sold.

  • 221 institutional investors held Ardelyx (ARDX) as of Q1 2025, up from 213 in Q4 2024.
  • Funds reported $809M of Ardelyx stock for Q1 2025, up 5.7% quarter-over-quarter.
  • 42 funds opened new Ardelyx positions in Q1 2025 and 32 closed out, a net change of +10 holders.
  • The largest Ardelyx buyer in Q1 2025 was Marshall Wace, an estimated $44.4M added.
  • The largest Ardelyx seller in Q1 2025 was Eventide Asset Management, an estimated $28.4M sold.

Based on aggregated 13F filings for Q1 2025.