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Aldeyra Therapeutics
ALDX

125 hedge funds and large institutions have $226M invested in Aldeyra Therapeutics in 2025 Q1 according to their latest regulatory filings, with 23 funds opening new positions, 27 increasing their positions, 47 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 1 → 2 (+1)

66% more call options, than puts

Call options by funds: $5.79M | Put options by funds: $3.49M

64% more first-time investments, than exits

New positions opened: 23 | Existing positions closed: 14

22% more capital invested

Capital invested by funds: $186M → $226M (+$40M)

6% more funds holding

Funds holding: 118 → 125 (+7)

1% more ownership

Funds ownership: 62.45% → 63.45% (+1%)

43% less repeat investments, than reductions

Existing positions increased: 27 | Existing positions reduced: 47

Holders
125
Holders Change
+7
Holders Change %
+5.93%
% of All Funds
1.68%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
23
Increased
27
Reduced
47
Closed
14
Calls
$5.79M
Puts
$3.49M
Net Calls
+$2.3M
Net Calls Change
+$857K

Top Buyers

1
KCM
Kingdon Capital Management
New York
+$4.6M
2
AAP
Ardsley Advisory Partners
Connecticut
+$3.55M
3
Invesco
Invesco
Georgia
+$2.79M
4
AQR Capital Management
AQR Capital Management
Connecticut
+$1.9M
5
N
Nuveen
North Carolina
+$1.29M

Top Sellers

1
ACM
ADAR1 Capital Management
Texas
-$2.58M
2
PI
PFG Investments
New York
-$1.75M
3
Raymond James Financial
Raymond James Financial
Florida
-$1.63M
4
KCM
Kennedy Capital Management
Missouri
-$1.39M
5
CM
Caption Management
Oklahoma
-$1.27M
Name Holding Trade Value Shares
Change 		Change in
Stake
Jane Street
26
Jane Street
New York
$1.02M +$1.05M +178,110 New
Group One Trading
27
Group One Trading
Illinois
$945K -$235K -39,740 -19%
TI
28
Trexquant Investment
Connecticut
$909K +$258K +43,637 +38%
D.E. Shaw & Co
29
D.E. Shaw & Co
New York
$872K -$218K -36,941 -20%
KCM
30
Kennondale Capital Management
Virginia
$870K – – –
Charles Schwab
31
Charles Schwab
California
$793K +$7.4K +1,252 +0.9%
Millennium Management
32
Millennium Management
New York
$777K -$158K -26,771 -17%
Goldman Sachs
33
Goldman Sachs
New York
$715K -$686K -115,969 -48%
Wellington Management Group
34
Wellington Management Group
Massachusetts
$675K +$694K +117,475 New
Renaissance Technologies
35
Renaissance Technologies
New York
$670K -$299K -50,500 -30%
Bank of New York Mellon
36
Bank of New York Mellon
New York
$638K -$34.6K -5,847 -5%
Acadian Asset Management
37
Acadian Asset Management
Massachusetts
$551K +$560K +94,681 +7,403%
UBS Group
38
UBS Group
Switzerland
$543K +$1.15K +195 +0.2%
SO
39
STRS Ohio
Ohio
$440K -$127K -21,400 -22%
RhumbLine Advisers
40
RhumbLine Advisers
Massachusetts
$434K -$16K -2,712 -3%
HWAM
41
Hennion & Walsh Asset Management
New Jersey
$399K -$94.6K -16,006 -19%
Susquehanna International Group
42
Susquehanna International Group
Pennsylvania
$376K -$156K -26,438 -29%
AllianceBernstein
43
AllianceBernstein
Tennessee
$337K – – –
Two Sigma Investments
44
Two Sigma Investments
New York
$318K -$450K -76,083 -58%
PI
45
PFG Investments
New York
$298K -$1.75M -295,997 -85%
Barclays
46
Barclays
United Kingdom
$293K -$144K -24,373 -32%
PAM
47
Panagora Asset Management
Massachusetts
$290K -$742K -125,554 -71%
LPL Financial
48
LPL Financial
California
$283K -$60.4K -10,220 -17%
IAIM
49
International Assets Investment Management
Florida
$280K -$65.7K -11,110 -19%
CAPTRUST Financial Advisors
50
CAPTRUST Financial Advisors
North Carolina
$271K +$157K +26,500 +128%
1
2
3 4 5

ALDX Hedge Fund Activity: Q1 2025 in Review

125 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Aldeyra Therapeutics (ALDX) for Q1 2025, worth a combined $226M — up 22% from $186M a quarter earlier.

Buyers outnumbered sellers: 23 funds opened new ALDX positions and 14 closed out — a net gain of 9 holders — while 27 added to existing stakes and 47 trimmed.

The largest buyer was Kingdon Capital Management, opening a new position worth an estimated $4.6M. The largest seller was ADAR1 Capital Management, cutting an estimated $2.58M.

  • 125 institutional investors held Aldeyra Therapeutics (ALDX) as of Q1 2025, up from 118 in Q4 2024.
  • Funds reported $226M of Aldeyra Therapeutics stock for Q1 2025, up 22% quarter-over-quarter.
  • 23 funds opened new Aldeyra Therapeutics positions in Q1 2025 and 14 closed out, a net change of +9 holders.
  • The largest Aldeyra Therapeutics buyer in Q1 2025 was Kingdon Capital Management, an estimated $4.6M added.
  • The largest Aldeyra Therapeutics seller in Q1 2025 was ADAR1 Capital Management, an estimated $2.58M sold.

Based on aggregated 13F filings for Q1 2025.