Adverum BiotechnologiesADVM
About: Adverum Biotechnologies Inc is a clinical-stage company that aims to establish gene therapy as a new standard of care for prevalent ocular diseases. It develops gene therapy product candidates intended to provide durable efficacy by inducing sustained expression of a therapeutic protein. Its product candidate, ixoberogene soroparvovec (Ixo-vec), is a single, in-office intravitreal (IVT) injection gene therapy product designed to deliver long-term durable therapeutic levels of aflibercept associated with a robust, sustained treatment response, reducing the treatment burden and fluctuations in macular fluid associated with bolus anti-vascular endothelial growth factor (VEGF) IVT injections.
Employees: 155
Fund manager confidence
Based on 2025 Q1 regulatory disclosures by fund managers ($100M+ AUM)
22% more first-time investments, than exits
New positions opened: 11 | Existing positions closed: 9
2.23% more ownership
Funds ownership: 76.32% [Q4 2024] → 78.54% (+2.23%) [Q1 2025]
1% more funds holding
Funds holding: 69 [Q4 2024] → 70 (+1) [Q1 2025]
0% more funds holding in top 10
Funds holding in top 10: 4 [Q4 2024] → 4 (+0) [Q1 2025]
6% less capital invested
Capital invested by funds: $74.1M [Q4 2024] → $69.8M (-$4.32M) [Q1 2025]
18% less repeat investments, than reductions
Existing positions increased: 18 | Existing positions reduced: 22
33% less call options, than puts
Call options by funds: $28K | Put options by funds: $42K
Research analyst outlook
3 Wall Street Analysts provided 1 year price targets over the past 3 months
3 analyst ratings
RBC Capital Luca Issi | 63%upside $4 | Sector Perform Maintained | 15 May 2025 |
Chardan Capital Daniil Gataulin | 1,241%upside $33 | Buy Maintained | 15 May 2025 |
HC Wainwright & Co. Matthew Caufield | 1,120%upside $30 | Buy Reiterated | 15 May 2025 |
Financial journalist opinion









