Achieve Life Sciences
ACHV
77 hedge funds and large institutions have $115M invested in Achieve Life Sciences in 2025 Q4 according to their latest regulatory filings, with 24 funds opening new positions, 24 increasing their positions, 12 reducing their positions, and 10 closing their positions.
548% more call options, than puts
Call options by funds: $1.39M | Put options by funds: $214K
140% more first-time investments, than exits
New positions opened: 24 | Existing positions closed: 10
136% more capital invested
Capital invested by funds: $48.9M → $115M (+$66.4M)
100% more repeat investments, than reductions
Existing positions increased: 24 | Existing positions reduced: 12
17% more funds holding
Funds holding: 66 → 77 (+11)
13.24% more ownership
Funds ownership: 30.41% → 43.66% (+13%)
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Franklin Resources
San Mateo,
California
|
+$18.9M |
| 2 |
Millennium Management
New York
|
+$4.89M |
| 3 |
Jane Street
New York
|
+$1.67M |
| 4 |
Two Sigma Investments
New York
|
+$1.35M |
| 5 |
LPL Financial
San Diego,
California
|
+$1.32M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
CC
Clearline Capital
New York
|
-$1.42M |
| 2 |
Squarepoint
New York
|
-$909K |
| 3 |
Renaissance Technologies
New York
|
-$690K |
| 4 |
Royal Bank of Canada
Toronto,
Ontario, Canada
|
-$668K |
| 5 |
Alyeska Investment Group
Chicago,
Illinois
|
-$562K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
AAP
76
Arax Advisory Partners
Denver,
Colorado
| $50 | – | – | – |
|
|
PFBT
77
Parkside Financial Bank & Trust
Saint Louis,
Missouri
| $25 | +$22 | +5 | New |
|
|
CC
78
Clearline Capital
New York
| – | -$1.42M | -451,219 | Closed |
|
|
79
Alyeska Investment Group
Chicago,
Illinois
| – | -$562K | -178,389 | Closed |
|
|
SCP
80
Sender Company & Partners
New York
| – | -$78.8K | -25,000 | Closed |
|
|
OAC
81
OMERS Administration Corp
Toronto,
Ontario, Canada
| – | -$77.8K | -24,700 | Closed |
|
|
OIA
82
OneDigital Investment Advisors
Overland Park,
Kansas
| – | -$63K | -20,000 | Closed |
|
|
BAM
83
Berkshire Asset Management
Wilkes Barre,
Pennsylvania
| – | -$55.8K | -17,700 | Closed |
|
84
Group One Trading
Chicago,
Illinois
| – | -$38.3K | -8,796 | Closed |
|
|
FIA
85
FNY Investment Advisers
New York
| – | -$15K | -5,000 | Closed |
|
|
SC
86
Stephens Consulting
Flint,
Michigan
| – | -$9.45K | -3,000 | Closed |
|
87
PNC Financial Services Group
Pittsburgh,
Pennsylvania
| – | -$2.6K | -826 | Closed |
|
ACHV Hedge Fund Activity: Q4 2025 in Review
77 of the 8,228 institutional investors tracked by Wall St. Rank reported a position in Achieve Life Sciences (ACHV) for Q4 2025, worth a combined $115M — up 136% from $48.9M a quarter earlier.
Buyers outnumbered sellers: 24 funds opened new ACHV positions and 10 closed out — a net gain of 14 holders — while 24 added to existing stakes and 12 trimmed.
The largest buyer was Franklin Resources, adding an estimated $18.9M. The largest seller was Clearline Capital, exiting entirely with an estimated $1.42M sold.
- 77 institutional investors held Achieve Life Sciences (ACHV) as of Q4 2025, up from 66 in Q3 2025.
- Funds reported $115M of Achieve Life Sciences stock for Q4 2025, up 136% quarter-over-quarter.
- 24 funds opened new Achieve Life Sciences positions in Q4 2025 and 10 closed out, a net change of +14 holders.
- The largest Achieve Life Sciences buyer in Q4 2025 was Franklin Resources, an estimated $18.9M added.
- The largest Achieve Life Sciences seller in Q4 2025 was Clearline Capital, an estimated $1.42M sold.
Based on aggregated 13F filings for Q4 2025.