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Abeona Therapeutics
ABEO

104 hedge funds and large institutions have $205M invested in Abeona Therapeutics in 2025 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 37 increasing their positions, 31 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 1 → 3 (+2)

143% more call options, than puts

Call options by funds: $8.88M | Put options by funds: $3.65M

22% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 18

19% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 31

9% more capital invested

Capital invested by funds: $188M → $205M (+$17.3M)

4% more funds holding

Funds holding: 100 → 104 (+4)

2.45% more ownership

Funds ownership: 69.4% → 71.85% (+2.4%)

Holders
104
Holders Change
+4
Holders Change %
+4%
% of All Funds
1.26%
Holding in Top 10
3
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+200%
% of All Funds
0.04%
New
22
Increased
37
Reduced
31
Closed
18
Calls
$8.88M
Puts
$3.65M
Net Calls
+$5.23M
Net Calls Change
-$1.39M

Top Buyers

1
ACM
AIGH Capital Management
Maryland
+$10.1M
2
CCC
Cable Car Capital
California
+$9.56M
3
TCM
Tang Capital Management
California
+$5.03M
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$3.53M
5
Aberdeen Group
Aberdeen Group
United Kingdom
+$3.1M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$16.1M
2
WSL
Western Standard LLC
California
-$6.6M
3
BCM
Boone Capital Management
Georgia
-$2.66M
4
Renaissance Technologies
Renaissance Technologies
New York
-$2.07M
5
Bank of America
Bank of America
North Carolina
-$2.04M
Name Holding Trade Value Shares
Change 		Change in
Stake
Morgan Stanley
26
Morgan Stanley
New York
$2.5M -$674K -133,980 -22%
Northern Trust
27
Northern Trust
Illinois
$2.21M -$14.6K -2,897 -0.7%
JGC
28
J. Goldman & Co
New York
$2.1M +$2.01M +398,916 New
JG
29
Jain Global
New York
$1.93M +$1.84M +366,067 New
Millennium Management
30
Millennium Management
New York
$1.81M -$1.84M -365,781 -52%
Group One Trading
31
Group One Trading
Illinois
$1.71M +$1.39M +275,986 +575%
KCM
32
Knoll Capital Management
Florida
$1.24M +$872K +173,264 +276%
Bank of New York Mellon
33
Bank of New York Mellon
New York
$1.02M -$98.6K -19,578 -9%
PFCS
34
Pale Fire Capital SE
Czech Republic
$921K +$879K +174,705 New
Fidelity Investments
35
Fidelity Investments
Massachusetts
$888K +$819K +162,671 +2,812%
PAM
36
Panagora Asset Management
Massachusetts
$879K +$31K +6,154 +4%
UBS Group
37
UBS Group
Switzerland
$845K +$162K +32,169 +25%
Los Angeles Capital Management
38
Los Angeles Capital Management
California
$787K -$266K -52,791 -25%
Charles Schwab
39
Charles Schwab
California
$700K -$3.31K -657 -0.5%
Citadel Advisors
40
Citadel Advisors
Florida
$673K -$734K -145,828 -53%
Renaissance Technologies
41
Renaissance Technologies
New York
$612K -$2.07M -410,237 -78%
AQR Capital Management
42
AQR Capital Management
Connecticut
$604K +$407K +80,908 +241%
PCM
43
Prelude Capital Management
New York
$586K +$318K +63,264 +132%
PAI
44
Palo Alto Investors
California
$574K – – –
D.E. Shaw & Co
45
D.E. Shaw & Co
New York
$558K -$103K -20,419 -16%
Barclays
46
Barclays
United Kingdom
$523K +$186K +37,014 +59%
Simplex Trading
47
Simplex Trading
Illinois
$518K +$330K +65,466 +200%
JF
48
Jump Financial
Illinois
$400K +$382K +75,940 New
SEI Investments
49
SEI Investments
Pennsylvania
$375K +$358K +71,153 New
LPL Financial
50
LPL Financial
California
$331K +$15.9K +3,165 +5%
1
2
3 4 5

ABEO Hedge Fund Activity: Q4 2025 in Review

104 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Abeona Therapeutics (ABEO) for Q4 2025, worth a combined $205M — up 9.2% from $188M a quarter earlier.

Buyers outnumbered sellers: 22 funds opened new ABEO positions and 18 closed out — a net gain of 4 holders — while 37 added to existing stakes and 31 trimmed.

The largest buyer was AIGH Capital Management, opening a new position worth an estimated $10.1M. The largest seller was Adage Capital Partners, exiting entirely with an estimated $16.1M sold.

  • 104 institutional investors held Abeona Therapeutics (ABEO) as of Q4 2025, up from 100 in Q3 2025.
  • Funds reported $205M of Abeona Therapeutics stock for Q4 2025, up 9.2% quarter-over-quarter.
  • 22 funds opened new Abeona Therapeutics positions in Q4 2025 and 18 closed out, a net change of +4 holders.
  • The largest Abeona Therapeutics buyer in Q4 2025 was AIGH Capital Management, an estimated $10.1M added.
  • The largest Abeona Therapeutics seller in Q4 2025 was Adage Capital Partners, an estimated $16.1M sold.

Based on aggregated 13F filings for Q4 2025.