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Woodline Partners Portfolio holdings

AUM $26.4B
1-Year Est. Return 44.85%
This Fund
S&P 500
This Quarter Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
Cap. Flow
+$3.3B
Cap. Flow %
12.77%
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147

Top Buys

Rank Stock Value
1
IVV icon
iShares Core S&P 500 ETF
IVV
+$997M
2
TXN icon
Texas Instruments
TXN
+$215M
3
NVDA icon
NVIDIA
NVDA
+$209M
4
VZ icon
Verizon
VZ
+$208M
5
APH icon
Amphenol
APH
+$143M

Top Sells

Rank Stock Value
1
T icon
AT&T
T
+$200M
2
MRUS
Merus
MRUS
+$158M
3
ALL icon
Allstate
ALL
+$141M
4
CB icon
Chubb
CB
+$115M
5
ARGX icon
argenx
ARGX
+$106M

Sector Composition

Rank Sector Weight
1 Healthcare 24.16%
2 Technology 23.32%
3 Financials 10.75%
4 Consumer Discretionary 10.22%
5 Communication Services 7.07%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PG icon
201
Procter & Gamble
PG
$338B
$33.9M 0.13%
236,476
-493,559
-68% -$72.8M
IMNM icon
202
Immunome
IMNM
$2.61B
$33.8M 0.13%
1,575,398
+300,669
+24% +$5.28M
CYBR
203
DELISTED
CyberArk
CYBR
$33.5M 0.13%
75,180
-23,726
-24% -$11.4M
JHX icon
204
James Hardie Industries
JHX
$16.1B
$33.3M 0.13%
1,603,746
+726,650
+83% +$14.6M
STAG icon
205
STAG Industrial
STAG
$7.44B
$33.1M 0.13%
899,137
-135,605
-13% -$5.15M
RDDT icon
206
Reddit
RDDT
$29.8B
$32.9M 0.13%
+143,306
New +$30.1M
DXCM icon
207
DexCom
DXCM
$32.9B
$32.9M 0.13%
495,570
+14,756
+3% +$954K
CRM icon
208
Salesforce
CRM
$152B
$32.9M 0.13%
124,005
-60,571
-33% -$15.1M
BG icon
209
Bunge Global
BG
$20.2B
$32.7M 0.13%
+366,726
New +$33.8M
FWRG icon
210
First Watch Restaurant Group
FWRG
$771M
$32.2M 0.12%
2,137,899
+838,783
+65% +$14.1M
GFL icon
211
GFL Environmental
GFL
$15.2B
$32M 0.12%
745,127
+666,217
+844% +$29.8M
LXEO icon
212
Lexeo Therapeutics
LXEO
$330M
$31.8M 0.12%
3,197,760
+625,598
+24% +$5.71M
GRDN
213
Guardian Pharmacy Services
GRDN
$2.58B
$31.7M 0.12%
1,053,906
– –
PEP icon
214
PepsiCo
PEP
$191B
$31.7M 0.12%
220,869
+39,930
+22% +$5.87M
MBX
215
MBX Biosciences
MBX
$3.07B
$31.5M 0.12%
1,000,063
-201,087
-17% -$4.88M
DD icon
216
DuPont de Nemours
DD
$19.1B
$31.5M 0.12%
261,290
-764,762
-75% -$86M
PVLA
217
Palvella Therapeutics
PVLA
$2.02B
$31.5M 0.12%
300,536
-45,213
-13% -$3.86M
URBN icon
218
Urban Outfitters
URBN
$6.65B
$31.4M 0.12%
+417,680
New +$29.5M
PJT icon
219
PJT Partners
PJT
$4.36B
$31.3M 0.12%
+187,248
New +$32M
CMA
220
DELISTED
Comerica
CMA
$31.3M 0.12%
+359,992
New +$29M
PRAX icon
221
Praxis Precision Medicines
PRAX
$8.52B
$31.1M 0.12%
105,412
-312,257
-75% -$58.1M
KALV
222
DELISTED
KalVista Pharmaceuticals
KALV
$31M 0.12%
1,921,092
+428
+0% +$5.67K
WAT icon
223
Waters Corp
WAT
$36.8B
$30.9M 0.12%
81,413
-34,052
-29% -$12.5M
ZVRA icon
224
Zevra Therapeutics
ZVRA
$594M
$30.9M 0.12%
3,450,844
-25,299
-0.7% -$239K
ABVX
225
Abivax
ABVX
$10.9B
$30.5M 0.12%
225,892
-85,150
-27% -$9.29M
7 8
9
10 11

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Woodline Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.

Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.

By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.

On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.

  • Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
  • Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
  • Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
  • Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
  • Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
  • Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
  • Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.

Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.