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Woodline Partners Portfolio holdings
AUM
$26.4B
1-Year Est. Return
44.85%
This Fund
S&P 500
This Quarter
Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
(+21%)
Cap. Flow
+$3.3B
Cap. Flow
% of AUM
12.77%
Top 10 Holdings %
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
iShares Core S&P 500 ETF
IVV
|
+$997M |
| 2 |
Texas Instruments
TXN
|
+$215M |
| 3 |
NVIDIA
NVDA
|
+$209M |
| 4 |
Verizon
VZ
|
+$208M |
| 5 |
Amphenol
APH
|
+$143M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
AT&T
T
|
+$200M |
| 2 |
MRUS
Merus
MRUS
|
+$158M |
| 3 |
Allstate
ALL
|
+$141M |
| 4 |
Chubb
CB
|
+$115M |
| 5 |
argenx
ARGX
|
+$106M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Healthcare | 24.16% |
| 2 | Technology | 23.32% |
| 3 | Financials | 10.75% |
| 4 | Consumer Discretionary | 10.22% |
| 5 | Communication Services | 7.07% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
1001
Darden Restaurants
DRI
$24.1B
| $208K | ﹤0.01% |
+1,130
| New | +$206K |
|
1002
LyondellBasell Industries
LYB
$19.8B
| $204K | ﹤0.01% |
+4,707
| New | +$213K |
|
1003
AN2 Therapeutics
ANTX
$219M
| $166K | ﹤0.01% |
+145,971
| New | +$170K |
|
1004
Snap
SNAP
$8.83B
| $160K | ﹤0.01% |
+19,842
| New | +$157K |
|
1005
Endava
DAVA
$154M
| $155K | ﹤0.01% |
24,522
-5,707
| -19% | -$43.7K |
|
|
CNH
1006
CNH Industrial
CNH
$17.4B
| $149K | ﹤0.01% |
+16,134
| New | +$161K |
|
1007
KALA BIO
KALA
$14.2M
| $125K | ﹤0.01% |
4,483
-466
| -9% | -$20.9K |
|
1008
Foghorn Therapeutics
FHTX
$327M
| $116K | ﹤0.01% |
21,523
-87,073
| -80% | -$395K |
|
|
CASI
1009
DELISTED
CASI Pharmaceuticals
CASI
| $113K | ﹤0.01% |
133,406
-32,234
| -19% | -$41.7K |
|
1010
Neumora Therapeutics
NMRA
$304M
| $26.8K | ﹤0.01% |
14,957
| – | – |
|
1011
Acadia Pharmaceuticals
ACAD
$4.9B
| – | – |
-151,453
| Closed | -$3.23M |
|
1012
Applied Industrial Technologies
AIT
$13.3B
| – | – |
-6,233
| Closed | -$1.63M |
|
|
AKRO
1013
DELISTED
Akero Therapeutics
AKRO
| – | – |
-639,598
| Closed | -$30.4M |
|
1014
Alight
ALIT
$411M
| – | – |
-3,131
| Closed | -$204K |
|
1015
Alarm.com
ALRM
$2.78B
| – | – |
-14,108
| Closed | -$749K |
|
1016
Autoliv
ALV
$8.83B
| – | – |
-99,009
| Closed | -$12.2M |
|
1017
AMN Healthcare
AMN
$1.19B
| – | – |
-990,514
| Closed | -$19.2M |
|
1018
AutoNation
AN
$6.99B
| – | – |
-54,544
| Closed | -$11.9M |
|
1019
Appian
APPN
$2.23B
| – | – |
-172,776
| Closed | -$5.28M |
|
1020
ArcBest
ARCB
$3.02B
| – | – |
-25,857
| Closed | -$1.81M |
|
1021
ARK Genomic Revolution ETF
ARKG
$1.63B
| – | – |
-74,571
| Closed | -$2.07M |
|
1022
Autohome
ATHM
$2.62B
| – | – |
-38,221
| Closed | -$1.09M |
|
1023
Avient
AVNT
$3.91B
| – | – |
-243,490
| Closed | -$8.02M |
|
1024
Avantor
AVTR
$8.91B
| – | – |
-1,628,501
| Closed | -$20.3M |
|
1025
Alibaba
BABA
$304B
| – | – |
-21,995
| Closed | -$3.93M |
|
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Woodline Partners's Q4 2025 Portfolio in Review
As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.
Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.
On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.
- Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
- Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
- Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
- Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
- Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
- Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
- Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.
Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.