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Woodline Partners Portfolio holdings
AUM
$26.4B
1-Year Est. Return
44.85%
This Fund
S&P 500
This Quarter
Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
(+21%)
Cap. Flow
+$3.3B
Cap. Flow
% of AUM
12.77%
Top 10 Holdings %
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
iShares Core S&P 500 ETF
IVV
|
+$997M |
| 2 |
Texas Instruments
TXN
|
+$215M |
| 3 |
NVIDIA
NVDA
|
+$209M |
| 4 |
Verizon
VZ
|
+$208M |
| 5 |
Amphenol
APH
|
+$143M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
AT&T
T
|
+$200M |
| 2 |
MRUS
Merus
MRUS
|
+$158M |
| 3 |
Allstate
ALL
|
+$141M |
| 4 |
Chubb
CB
|
+$115M |
| 5 |
argenx
ARGX
|
+$106M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Healthcare | 24.16% |
| 2 | Technology | 23.32% |
| 3 | Financials | 10.75% |
| 4 | Consumer Discretionary | 10.22% |
| 5 | Communication Services | 7.07% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
801
Commault Systems
CVLT
$5.59B
| $1.59M | 0.01% |
12,684
-84,273
| -87% | -$11.9M |
|
802
AES
AES
$10.5B
| $1.55M | 0.01% |
108,378
+14,367
| +15% | +$203K |
|
803
Ametek
AME
$57.9B
| $1.55M | 0.01% |
7,565
-80,289
| -91% | -$15.6M |
|
804
Iovance Biotherapeutics
IOVA
$2.74B
| $1.55M | 0.01% |
567,680
| – | – |
|
805
Norwegian Cruise Line
NCLH
$8.85B
| $1.55M | 0.01% |
69,286
+9,618
| +16% | +$203K |
|
806
Wynn Resorts
WYNN
$10.6B
| $1.55M | 0.01% |
12,849
+1,702
| +15% | +$211K |
|
807
Kura Oncology
KURA
$848M
| $1.51M | 0.01% |
145,704
| – | – |
|
808
4D Molecular Therapeutics
FDMT
$561M
| $1.5M | 0.01% |
+200,001
| New | +$2.03M |
|
809
Entrada Therapeutics
TRDA
$265M
| $1.46M | 0.01% |
+142,110
| New | +$1.2M |
|
|
BETA
810
Beta Technologies Inc
BETA
$5.37B
| $1.41M | 0.01% |
+50,000
| New | +$1.49M |
|
|
BLLN
811
BillionToOne Inc
BLLN
$4.4B
| $1.39M | 0.01% |
+17,000
| New | +$1.72M |
|
812
Benitec Biopharma
BNTC
$463M
| $1.36M | 0.01% |
+100,704
| New | +$1.39M |
|
813
Molina Healthcare
MOH
$10.2B
| $1.36M | 0.01% |
+7,813
| New | +$1.28M |
|
814
Cigna
CI
$74.5B
| $1.34M | 0.01% |
+4,884
| New | +$1.37M |
|
815
3M
MMM
$94.4B
| $1.32M | 0.01% |
8,234
-11,539
| -58% | -$1.89M |
|
816
Veeva Systems
VEEV
$37B
| $1.31M | 0.01% |
+5,877
| New | +$1.56M |
|
817
Cohu
COHU
$2.49B
| $1.31M | 0.01% |
56,148
+20,615
| +58% | +$472K |
|
818
Alexandria Real Estate Equities
ARE
$8.55B
| $1.3M | 0.01% |
26,540
+5,967
| +29% | +$351K |
|
|
BBOT
819
BridgeBio Oncology
BBOT
$745M
| $1.3M | 0.01% |
103,707
| – | – |
|
|
ANDG
820
Andersen Group
ANDG
$5.55B
| $1.3M | 0.01% |
+50,000
| New | +$1.26M |
|
|
JBIO
821
Jade Biosciences
JBIO
$1.34B
| $1.27M | ﹤0.01% |
+82,056
| New | +$963K |
|
822
Conagra Brands
CAG
$7.2B
| $1.26M | ﹤0.01% |
72,801
+9,553
| +15% | +$170K |
|
823
American Tower
AMT
$80.2B
| $1.25M | ﹤0.01% |
+7,126
| New | +$1.3M |
|
824
Elevance Health
ELV
$85.6B
| $1.23M | ﹤0.01% |
+3,523
| New | +$1.19M |
|
825
TE Connectivity
TEL
$62.5B
| $1.23M | ﹤0.01% |
+5,405
| New | +$1.25M |
|
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Woodline Partners's Q4 2025 Portfolio in Review
As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.
Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.
On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.
- Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
- Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
- Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
- Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
- Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
- Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
- Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.
Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.