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Woodline Partners Portfolio holdings

AUM $26.4B
1-Year Est. Return 44.85%
This Fund
S&P 500
This Quarter Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
Cap. Flow
+$3.3B
Cap. Flow %
12.77%
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147

Top Buys

Rank Stock Value
1
IVV icon
iShares Core S&P 500 ETF
IVV
+$997M
2
TXN icon
Texas Instruments
TXN
+$215M
3
NVDA icon
NVIDIA
NVDA
+$209M
4
VZ icon
Verizon
VZ
+$208M
5
APH icon
Amphenol
APH
+$143M

Top Sells

Rank Stock Value
1
T icon
AT&T
T
+$200M
2
MRUS
Merus
MRUS
+$158M
3
ALL icon
Allstate
ALL
+$141M
4
CB icon
Chubb
CB
+$115M
5
ARGX icon
argenx
ARGX
+$106M

Sector Composition

Rank Sector Weight
1 Healthcare 24.16%
2 Technology 23.32%
3 Financials 10.75%
4 Consumer Discretionary 10.22%
5 Communication Services 7.07%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DNLI icon
776
Denali Therapeutics
DNLI
$3.89B
$1.88M 0.01%
114,082
+565
+0.5% +$9.54K
TMUS icon
777
T-Mobile US
TMUS
$190B
$1.88M 0.01%
+9,264
New +$1.96M
EYPT icon
778
EyePoint Inc
EYPT
$1.19B
$1.84M 0.01%
100,463
+200
+0.2% +$2.83K
BTU icon
779
Peabody Energy
BTU
$2.89B
$1.83M 0.01%
+61,513
New +$1.81M
NTLA icon
780
Intellia Therapeutics
NTLA
$1.66B
$1.81M 0.01%
200,998
– –
SLDB icon
781
Solid Biosciences
SLDB
$840M
$1.79M 0.01%
316,823
-315,000
-50% -$1.71M
SJM icon
782
J.M. Smucker
SJM
$12.8B
$1.78M 0.01%
18,202
+4,103
+29% +$424K
IVZ icon
783
Invesco
IVZ
$14B
$1.78M 0.01%
67,739
+8,859
+15% +$216K
SPRY icon
784
ARS Pharmaceuticals
SPRY
$599M
$1.76M 0.01%
150,936
– –
TENX icon
785
Tenax Therapeutics
TENX
$519M
$1.75M 0.01%
143,481
+55,270
+63% +$481K
TROW icon
786
T. Rowe Price
TROW
$24.3B
$1.73M 0.01%
16,918
-12,120
-42% -$1.25M
NGNE icon
787
Neurogene
NGNE
$713M
$1.73M 0.01%
83,835
– –
EPAM icon
788
EPAM Systems
EPAM
$5.06B
$1.72M 0.01%
8,407
-25,473
-75% -$4.54M
FMC icon
789
FMC
FMC
$1.33B
$1.7M 0.01%
+122,629
New +$2.34M
MELI icon
790
Mercado Libre
MELI
$91.7B
$1.69M 0.01%
+841
New +$1.77M
NWSA icon
791
News Corp Class A
NWSA
$15.5B
$1.67M 0.01%
63,921
+14,170
+28% +$372K
HAS icon
792
Hasbro
HAS
$13.1B
$1.66M 0.01%
20,290
+2,701
+15% +$212K
SPOT icon
793
Spotify
SPOT
$101B
$1.66M 0.01%
+2,852
New +$1.78M
FDS icon
794
Factset
FDS
$10B
$1.65M 0.01%
5,700
+703
+14% +$197K
FOX icon
795
Fox Class B
FOX
$23.9B
$1.65M 0.01%
25,409
+7,972
+46% +$465K
PNW icon
796
Pinnacle West Capital
PNW
$12.3B
$1.62M 0.01%
18,216
+2,448
+16% +$219K
ETON icon
797
Eton Pharmaceutcials
ETON
$1.24B
$1.61M 0.01%
+95,487
New +$1.68M
BMEA icon
798
Biomea Fusion
BMEA
$92.1M
$1.61M 0.01%
1,300,834
– –
LENZ
799
LENZ Therapeutics
LENZ
$167M
$1.6M 0.01%
+100,000
New +$2.91M
STOK icon
800
Stoke Therapeutics
STOK
$2.08B
$1.59M 0.01%
50,120
-45,000
-47% -$1.35M
30 31
32
33 34

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Woodline Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.

Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.

By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.

On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.

  • Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
  • Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
  • Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
  • Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
  • Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
  • Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
  • Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.

Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.