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Woodline Partners Portfolio holdings
AUM
$26.4B
1-Year Est. Return
44.85%
This Fund
S&P 500
This Quarter
Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
(+21%)
Cap. Flow
+$3.3B
Cap. Flow
% of AUM
12.77%
Top 10 Holdings %
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
iShares Core S&P 500 ETF
IVV
|
+$997M |
| 2 |
Texas Instruments
TXN
|
+$215M |
| 3 |
NVIDIA
NVDA
|
+$209M |
| 4 |
Verizon
VZ
|
+$208M |
| 5 |
Amphenol
APH
|
+$143M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
AT&T
T
|
+$200M |
| 2 |
MRUS
Merus
MRUS
|
+$158M |
| 3 |
Allstate
ALL
|
+$141M |
| 4 |
Chubb
CB
|
+$115M |
| 5 |
argenx
ARGX
|
+$106M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Healthcare | 24.16% |
| 2 | Technology | 23.32% |
| 3 | Financials | 10.75% |
| 4 | Consumer Discretionary | 10.22% |
| 5 | Communication Services | 7.07% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
751
MeiraGTx Holdings
MGTX
$1.2B
| $2.39M | 0.01% |
300,323
+100,000
| +50% | +$831K |
|
752
SM Energy
SM
$6.91B
| $2.37M | 0.01% |
126,475
-2,303,043
| -95% | -$46.7M |
|
753
Dyne Therapeutics
DYN
$4.88B
| $2.36M | 0.01% |
+120,788
| New | +$2.29M |
|
754
Weyerhaeuser
WY
$18.5B
| $2.33M | 0.01% |
98,213
-799,543
| -89% | -$18.5M |
|
|
OTGAU
755
OTG Acquisition Corp I Unit
OTGAU
| $2.29M | 0.01% |
225,000
| – | – |
|
756
enGene Therapeutics
ENGN
$121M
| $2.26M | 0.01% |
+250,000
| New | +$2M |
|
757
Jack Henry & Associates
JKHY
$11.1B
| $2.25M | 0.01% |
12,354
+2,730
| +28% | +$455K |
|
758
Aclaris Therapeutics
ACRS
$823M
| $2.23M | 0.01% |
+742,009
| New | +$1.87M |
|
|
BRR
759
ProCap Financial Inc
BRR
$161M
| $2.21M | 0.01% |
625,000
+125,000
| +25% | +$997K |
|
760
Nordson
NDSN
$17.3B
| $2.19M | 0.01% |
9,107
+2,012
| +28% | +$473K |
|
761
Rigel Pharmaceuticals
RIGL
$754M
| $2.14M | 0.01% |
+50,000
| New | +$1.88M |
|
762
Rush Enterprises Class A
RUSHA
$6.25B
| $2.13M | 0.01% |
39,472
-164,490
| -81% | -$8.55M |
|
763
Clorox
CLX
$12.8B
| $2.1M | 0.01% |
20,808
+4,644
| +29% | +$504K |
|
764
Ralph Lauren
RL
$23.6B
| $2.09M | 0.01% |
5,899
+790
| +15% | +$269K |
|
765
Amer Sports
AS
$21.6B
| $2.04M | 0.01% |
54,542
+19,542
| +56% | +$670K |
|
766
Cheesecake Factory
CAKE
$5.32B
| $2.03M | 0.01% |
40,199
-577,857
| -93% | -$29M |
|
767
Agios Pharmaceuticals
AGIO
$1.93B
| $2.03M | 0.01% |
74,423
+427
| +0.6% | +$15K |
|
768
Oric Pharmaceuticals
ORIC
$1.38B
| $2.02M | 0.01% |
246,534
| – | – |
|
|
DFTX
769
Definium Therapeutics
DFTX
$6.04B
| $2.02M | 0.01% |
+150,570
| New | +$1.86M |
|
770
Solventum
SOLV
$14.1B
| $2.01M | 0.01% |
25,307
+5,828
| +30% | +$446K |
|
771
Cognizant
CTSH
$26.2B
| $1.96M | 0.01% |
23,638
+4,490
| +23% | +$336K |
|
772
Humacyte
HUMA
$195M
| $1.92M | 0.01% |
2,002,073
| – | – |
|
773
Akamai
AKAM
$16.2B
| $1.91M | 0.01% |
21,895
+91
| +0.4% | +$7.49K |
|
774
Healthpeak Properties
DOC
$14.7B
| $1.91M | 0.01% |
118,571
+26,729
| +29% | +$471K |
|
775
Jasper Therapeutics
JSPR
$24.3M
| $1.9M | 0.01% |
1,040,704
+953
| +0.1% | +$1.91K |
|
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Woodline Partners's Q4 2025 Portfolio in Review
As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.
Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.
On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.
- Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
- Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
- Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
- Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
- Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
- Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
- Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.
Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.