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Woodline Partners Portfolio holdings

AUM $26.4B
1-Year Est. Return 44.85%
This Fund
S&P 500
This Quarter Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
Cap. Flow
+$3.3B
Cap. Flow %
12.77%
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147

Top Buys

Rank Stock Value
1
IVV icon
iShares Core S&P 500 ETF
IVV
+$997M
2
TXN icon
Texas Instruments
TXN
+$215M
3
NVDA icon
NVIDIA
NVDA
+$209M
4
VZ icon
Verizon
VZ
+$208M
5
APH icon
Amphenol
APH
+$143M

Top Sells

Rank Stock Value
1
T icon
AT&T
T
+$200M
2
MRUS
Merus
MRUS
+$158M
3
ALL icon
Allstate
ALL
+$141M
4
CB icon
Chubb
CB
+$115M
5
ARGX icon
argenx
ARGX
+$106M

Sector Composition

Rank Sector Weight
1 Healthcare 24.16%
2 Technology 23.32%
3 Financials 10.75%
4 Consumer Discretionary 10.22%
5 Communication Services 7.07%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ARDT
601
Ardent Health
ARDT
$1.67B
$5.66M 0.02%
641,232
– –
GRMN
602
Garmin
GRMN
$58.7B
$5.66M 0.02%
+27,896
New +$6.07M
CCL icon
603
Carnival Corporation Ltd
CCL
$39.2B
$5.64M 0.02%
184,598
+41,117
+29% +$1.15M
FIX icon
604
Comfort Systems
FIX
$60.7B
$5.61M 0.02%
+6,006
New +$5.55M
EWTX icon
605
Edgewise Therapeutics
EWTX
$4.69B
$5.56M 0.02%
224,192
+2
+0% +$40
REPL icon
606
Replimune Group
REPL
$1.04B
$5.55M 0.02%
570,988
-285,000
-33% -$2.42M
MEOH icon
607
Methanex
MEOH
$4.09B
$5.54M 0.02%
+139,576
New +$5.19M
AAL icon
608
American Airlines Group
AAL
$10.6B
$5.52M 0.02%
+359,972
New +$4.86M
DIN icon
609
Dine Brands
DIN
$440M
$5.47M 0.02%
+170,232
New +$4.94M
EQ icon
610
Equillium
EQ
$137M
$5.43M 0.02%
3,500,901
-7,870
-0.2% -$9.59K
HPE icon
611
Hewlett Packard
HPE
$68.3B
$5.41M 0.02%
225,122
+51,698
+30% +$1.22M
SANA icon
612
Sana Biotechnology
SANA
$968M
$5.36M 0.02%
1,317,641
-60,595
-4% -$271K
VRSK icon
613
Verisk Analytics
VRSK
$24.6B
$5.32M 0.02%
23,786
+5,321
+29% +$1.2M
MTB icon
614
M&T Bank
MTB
$35.9B
$5.29M 0.02%
26,270
+5,617
+27% +$1.07M
FITB
615
Fifth Third Bancorp
FITB
$51.4B
$5.28M 0.02%
112,797
+25,320
+29% +$1.11M
ACET icon
616
Adicet Bio
ACET
$77.3M
$5.26M 0.02%
+625,000
New +$6.91M
CBT icon
617
Cabot Corp
CBT
$4.5B
$5.22M 0.02%
+78,695
New +$5.24M
NRG icon
618
NRG Energy
NRG
$25.4B
$5.21M 0.02%
32,730
+7,166
+28% +$1.19M
SRZN icon
619
Surrozen
SRZN
$283M
$5.21M 0.02%
230,572
+182,379
+378% +$2.95M
MUR icon
620
Murphy Oil
MUR
$4.74B
$5.19M 0.02%
+166,177
New +$5M
XME icon
621
State Street SPDR S&P Metals & Mining ETF
XME
$4.39B
$5.16M 0.02%
+49,783
New +$4.92M
SYF icon
622
Synchrony
SYF
$25.5B
$5.15M 0.02%
61,671
+12,498
+25% +$955K
VICI icon
623
VICI Properties
VICI
$29.3B
$5.13M 0.02%
182,313
+41,381
+29% +$1.23M
OXY icon
624
Occidental Petroleum
OXY
$55.3B
$5.06M 0.02%
123,061
-140,264
-53% -$5.85M
DG icon
625
Dollar General
DG
$28B
$4.99M 0.02%
37,554
+8,469
+29% +$945K
23 24
25
26 27

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Woodline Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.

Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.

By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.

On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.

  • Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
  • Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
  • Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
  • Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
  • Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
  • Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
  • Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.

Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.