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Woodline Partners Portfolio holdings

AUM $26.4B
1-Year Est. Return 44.85%
This Fund
S&P 500
This Quarter Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
Cap. Flow
+$3.3B
Cap. Flow %
12.77%
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147

Top Buys

Rank Stock Value
1
IVV icon
iShares Core S&P 500 ETF
IVV
+$997M
2
TXN icon
Texas Instruments
TXN
+$215M
3
NVDA icon
NVIDIA
NVDA
+$209M
4
VZ icon
Verizon
VZ
+$208M
5
APH icon
Amphenol
APH
+$143M

Top Sells

Rank Stock Value
1
T icon
AT&T
T
+$200M
2
MRUS
Merus
MRUS
+$158M
3
ALL icon
Allstate
ALL
+$141M
4
CB icon
Chubb
CB
+$115M
5
ARGX icon
argenx
ARGX
+$106M

Sector Composition

Rank Sector Weight
1 Healthcare 24.16%
2 Technology 23.32%
3 Financials 10.75%
4 Consumer Discretionary 10.22%
5 Communication Services 7.07%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
VCEL icon
476
Vericel Corp
VCEL
$2.31B
$9.56M 0.04%
265,384
-1,817
-0.7% -$66.8K
LOAR icon
477
Loar Holdings
LOAR
$6.64B
$9.47M 0.04%
139,210
– –
LKQ icon
478
LKQ Corp
LKQ
$6.29B
$9.34M 0.04%
309,144
+192,661
+165% +$5.81M
PYPL icon
479
PayPal
PYPL
$50.5B
$9.29M 0.04%
159,122
-290,566
-65% -$18.9M
ALEX
480
DELISTED
Alexander & Baldwin
ALEX
$9.29M 0.04%
+449,990
New +$7.82M
IDXX icon
481
Idexx Laboratories
IDXX
$46.2B
$9.22M 0.04%
13,627
+3,053
+29% +$2.08M
KMI icon
482
Kinder Morgan
KMI
$68.7B
$9.2M 0.04%
334,809
+76,371
+30% +$2.06M
FBRX icon
483
Forte Biosciences
FBRX
$1.57B
$9.05M 0.04%
331,987
– –
PNTG icon
484
Pennant Group
PNTG
$1.36B
$8.98M 0.03%
+318,948
New +$8.48M
HBM icon
485
Hudbay
HBM
$12.3B
$8.9M 0.03%
448,553
+42,183
+10% +$713K
PSX icon
486
Phillips 66
PSX
$81.4B
$8.87M 0.03%
68,768
+15,358
+29% +$2.07M
PAR icon
487
PAR Technology
PAR
$735M
$8.86M 0.03%
+244,321
New +$8.82M
DSGN icon
488
Design Therapeutics
DSGN
$876M
$8.86M 0.03%
944,039
+331,327
+54% +$2.59M
O icon
489
Realty Income
O
$59.1B
$8.84M 0.03%
156,849
+36,014
+30% +$2.09M
VST icon
490
Vistra
VST
$47.4B
$8.83M 0.03%
54,716
+12,621
+30% +$2.3M
URI icon
491
United Rentals
URI
$72.4B
$8.8M 0.03%
10,870
+2,366
+28% +$2.05M
DNTH icon
492
Dianthus Therapeutics
DNTH
$6.09B
$8.78M 0.03%
213,087
+170,389
+399% +$6.61M
SYRE icon
493
Spyre Therapeutics
SYRE
$9.25B
$8.71M 0.03%
265,892
+134,016
+102% +$3.5M
COIN icon
494
Coinbase
COIN
$40.5B
$8.71M 0.03%
38,495
+8,609
+29% +$2.57M
SAIL
495
SailPoint Inc
SAIL
$10.6B
$8.67M 0.03%
428,371
– –
GPCR icon
496
Structure Therapeutics
GPCR
$3.78B
$8.62M 0.03%
123,902
+58,462
+89% +$2.39M
VNO icon
497
Vornado Realty Trust
VNO
$7.38B
$8.59M 0.03%
+258,194
New +$9.43M
NUVB icon
498
Nuvation Bio
NUVB
$2.32B
$8.58M 0.03%
957,914
+2,500
+0.3% +$15.5K
AVAH icon
499
Aveanna Healthcare
AVAH
$2.07B
$8.58M 0.03%
+1,050,277
New +$9.49M
HST icon
500
Host Hotels & Resorts
HST
$16B
$8.58M 0.03%
483,850
-2,462,858
-84% -$42.5M
18 19
20
21 22

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Woodline Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.

Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.

By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.

On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.

  • Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
  • Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
  • Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
  • Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
  • Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
  • Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
  • Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.

Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.