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Woodline Partners Portfolio holdings

AUM $26.4B
1-Year Est. Return 44.85%
This Fund
S&P 500
This Quarter Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
Cap. Flow
+$3.3B
Cap. Flow %
12.77%
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147

Top Buys

Rank Stock Value
1
IVV icon
iShares Core S&P 500 ETF
IVV
+$997M
2
TXN icon
Texas Instruments
TXN
+$215M
3
NVDA icon
NVIDIA
NVDA
+$209M
4
VZ icon
Verizon
VZ
+$208M
5
APH icon
Amphenol
APH
+$143M

Top Sells

Rank Stock Value
1
T icon
AT&T
T
+$200M
2
MRUS
Merus
MRUS
+$158M
3
ALL icon
Allstate
ALL
+$141M
4
CB icon
Chubb
CB
+$115M
5
ARGX icon
argenx
ARGX
+$106M

Sector Composition

Rank Sector Weight
1 Healthcare 24.16%
2 Technology 23.32%
3 Financials 10.75%
4 Consumer Discretionary 10.22%
5 Communication Services 7.07%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NXPI icon
26
NXP Semiconductors
NXPI
$57.8B
$145M 0.56%
669,443
-3,960
-0.6% -$849K
ADSK icon
27
Autodesk
ADSK
$49.5B
$145M 0.56%
490,450
+7,059
+1% +$2.14M
AJG icon
28
Arthur J. Gallagher & Co
AJG
$64.1B
$139M 0.54%
+535,602
New +$142M
PTGX icon
29
Protagonist Therapeutics
PTGX
$8.79B
$123M 0.48%
1,408,772
-29,475
-2% -$2.41M
DHR icon
30
Danaher
DHR
$137B
$122M 0.47%
533,910
+23,324
+5% +$5.13M
CB icon
31
Chubb
CB
$135B
$121M 0.47%
387,909
-392,312
-50% -$115M
TJX icon
32
TJX Companies
TJX
$174B
$120M 0.47%
783,107
+635,666
+431% +$94M
TMO icon
33
Thermo Fisher Scientific
TMO
$213B
$120M 0.46%
206,349
+167,411
+430% +$94.7M
LIN icon
34
Linde
LIN
$221B
$116M 0.45%
272,513
+250,689
+1,149% +$107M
AMP icon
35
Ameriprise Financial
AMP
$48.3B
$115M 0.45%
235,328
+42,043
+22% +$20M
SNOW icon
36
Snowflake
SNOW
$102B
$112M 0.43%
511,472
+5,889
+1% +$1.44M
IBM icon
37
IBM
IBM
$211B
$112M 0.43%
376,712
+121,174
+47% +$36.3M
CVS icon
38
CVS Health
CVS
$133B
$111M 0.43%
1,397,302
+695,554
+99% +$54.8M
NFLX icon
39
Netflix
NFLX
$299B
$110M 0.43%
1,177,293
+103,083
+10% +$11.1M
UNM icon
40
Unum
UNM
$13.6B
$109M 0.42%
1,412,830
+747,665
+112% +$57.2M
DIS icon
41
Walt Disney
DIS
$167B
$108M 0.42%
947,104
+941,030
+15,493% +$104M
MRK icon
42
Merck
MRK
$322B
$106M 0.41%
1,004,699
+96,155
+11% +$9.03M
CYTK icon
43
Cytokinetics
CYTK
$10.5B
$105M 0.41%
1,648,428
+703
+0% +$43.7K
PCOR icon
44
Procore
PCOR
$8.26B
$104M 0.4%
1,436,508
-353,695
-20% -$26.2M
CCI icon
45
Crown Castle
CCI
$33.3B
$104M 0.4%
1,172,987
+175,561
+18% +$16.1M
EQIX icon
46
Equinix
EQIX
$101B
$104M 0.4%
135,935
-34,264
-20% -$26.9M
LH icon
47
Labcorp
LH
$25B
$102M 0.39%
405,036
+117,890
+41% +$31.3M
V icon
48
Visa
V
$684B
$101M 0.39%
288,143
-34,582
-11% -$11.8M
RGA icon
49
Reinsurance Group of America
RGA
$15.5B
$97.7M 0.38%
+480,380
New +$92.9M
JCI icon
50
Johnson Controls International
JCI
$88.8B
$94.8M 0.37%
791,350
-286,646
-27% -$32.9M
1
2
3 4 5

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Woodline Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.

Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.

By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.

On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.

  • Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
  • Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
  • Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
  • Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
  • Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
  • Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
  • Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.

Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.