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Woodline Partners Portfolio holdings

AUM $26.4B
1-Year Est. Return 44.85%
This Fund
S&P 500
This Quarter Est. Return
+9.88%
1 Year Est. Return
+44.85%
3 Year Est. Return
+131.23%
5 Year Est. Return
+174.12%
10 Year Est. Return
–
AUM
$25.8B
AUM Growth
+$4.56B
Cap. Flow
+$3.3B
Cap. Flow %
12.77%
Top 10 Hldgs %
19.43%
Holding
1,157
New
287
Increased
424
Reduced
242
Closed
147

Top Buys

Rank Stock Value
1
IVV icon
iShares Core S&P 500 ETF
IVV
+$997M
2
TXN icon
Texas Instruments
TXN
+$215M
3
NVDA icon
NVIDIA
NVDA
+$209M
4
VZ icon
Verizon
VZ
+$208M
5
APH icon
Amphenol
APH
+$143M

Top Sells

Rank Stock Value
1
T icon
AT&T
T
+$200M
2
MRUS
Merus
MRUS
+$158M
3
ALL icon
Allstate
ALL
+$141M
4
CB icon
Chubb
CB
+$115M
5
ARGX icon
argenx
ARGX
+$106M

Sector Composition

Rank Sector Weight
1 Healthcare 24.16%
2 Technology 23.32%
3 Financials 10.75%
4 Consumer Discretionary 10.22%
5 Communication Services 7.07%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
IMTX icon
451
Immatics
IMTX
$1.29B
$10.5M 0.04%
1,000,597
-841,005
-46% -$8.49M
PHM icon
452
Pultegroup
PHM
$24.7B
$10.5M 0.04%
89,394
-325,551
-78% -$39.9M
ELAN icon
453
Elanco Animal Health
ELAN
$12.1B
$10.5M 0.04%
462,390
-3,207,113
-87% -$69.8M
SWKS icon
454
Skyworks Solutions
SWKS
$10.1B
$10.5M 0.04%
+164,866
New +$11.5M
PRME icon
455
Prime Medicine
PRME
$533M
$10.4M 0.04%
3,002,844
+362
+0% +$1.61K
SPG icon
456
Simon Property Group
SPG
$71.9B
$10.3M 0.04%
55,700
-84,892
-60% -$15.4M
NATL icon
457
NCR Atleos
NATL
$3.43B
$10.3M 0.04%
+270,515
New +$10.1M
NBIX icon
458
Neurocrine Biosciences
NBIX
$16.2B
$10.3M 0.04%
+72,298
New +$10.5M
AMLX icon
459
Amylyx Pharmaceuticals
AMLX
$2.69B
$10.2M 0.04%
845,408
+118
+0% +$1.6K
CERT icon
460
Certara
CERT
$1.24B
$10.2M 0.04%
+1,157,286
New +$11.9M
VIAV icon
461
Viavi Solutions
VIAV
$10B
$10.1M 0.04%
568,215
-4,438,187
-89% -$71.7M
TXRH icon
462
Texas Roadhouse
TXRH
$13.7B
$10M 0.04%
60,328
– –
ROST icon
463
Ross Stores
ROST
$81.6B
$10M 0.04%
55,489
+12,262
+28% +$2.05M
CTMX icon
464
CytomX Therapeutics
CTMX
$734M
$9.96M 0.04%
2,337,005
– –
GERN icon
465
Geron
GERN
$1.01B
$9.91M 0.04%
7,504,094
+1,620,302
+28% +$2.03M
ABNB icon
466
Airbnb
ABNB
$90B
$9.86M 0.04%
+72,633
New +$9.05M
NOC icon
467
Northrop Grumman
NOC
$80.7B
$9.84M 0.04%
17,258
-10,831
-39% -$6.29M
SRE icon
468
Sempra
SRE
$55.1B
$9.83M 0.04%
111,355
+25,123
+29% +$2.29M
SLB icon
469
SLB Ltd
SLB
$76.5B
$9.78M 0.04%
254,885
+57,705
+29% +$2.09M
EOG icon
470
EOG Resources
EOG
$71.4B
$9.73M 0.04%
92,639
+20,480
+28% +$2.2M
ENOV icon
471
Enovis
ENOV
$1.51B
$9.72M 0.04%
364,895
– –
STEP icon
472
StepStone Group
STEP
$4.14B
$9.68M 0.04%
+150,870
New +$9.54M
HL icon
473
Hecla Mining
HL
$10.7B
$9.67M 0.04%
+504,158
New +$7.7M
AZO icon
474
AutoZone
AZO
$50.1B
$9.63M 0.04%
2,839
+628
+28% +$2.37M
ADI icon
475
Analog Devices
ADI
$184B
$9.61M 0.04%
35,440
+4,217
+14% +$1.06M
17 18
19
20 21

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Woodline Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Woodline Partners held 1,157 positions worth $25.8B, up 21% from $21.2B the previous quarter. Its ten largest holdings account for 19% of the portfolio.

Woodline Partners deployed $3.3B of net new capital in Q4 2025, opening 287 new positions and adding to 424 existing holdings. Its largest new stake was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.

By sector, the portfolio is most concentrated in Healthcare at 24% of assets, up from 24% a quarter earlier, followed by Technology and Financials.

On the sell side, the largest reduction was AT&T, an estimated $200M trimmed.

  • Woodline Partners's largest Q4 2025 buy was iShares Core S&P 500 ETF: 1,467,676 shares worth $1.01B.
  • Woodline Partners added most to Texas Instruments in Q4 2025, an estimated $215M increase.
  • Woodline Partners's biggest Q4 2025 reduction was AT&T, cutting an estimated $200M.
  • Woodline Partners fully exited Merus in Q4 2025, selling an estimated $158M.
  • Woodline Partners's ten largest holdings make up 19% of its $25.8B portfolio in Q4 2025.
  • Woodline Partners opened 287 new positions and closed 147 in Q4 2025.
  • Woodline Partners's portfolio value rose 21% quarter-over-quarter to $25.8B.

Based on Woodline Partners's 13F filing for Q4 2025, filed 17 Feb 2026.